SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oac'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_A_IBPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3oac GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Mentha
x
piperita) 		5 / 9 VAL B 138
LEU B 193
ILE B  69
ALA B  68
LEU B 120
 None
 1.18A 1eqgA-3oacB:
0.7		 1eqgA-3oacB:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1291_1
(FICOLIN-2)		 3oac GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Mentha
x
piperita) 		4 / 6 SER B 123
LEU B 120
ASP B 131
ASP B 125
 None
 1.19A 2j2pE-3oacB:
undetectable
2j2pF-3oacB:
undetectable		 2j2pE-3oacB:
20.45
2j2pF-3oacB:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YY8_B_SAMB500_0
(UPF0106 PROTEIN
PH0461)		 3oac GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Mentha
x
piperita) 		5 / 11 LEU B 107
VAL B 104
GLY B 101
HIS B  79
GLU B 105
 None
 1.17A 2yy8A-3oacB:
undetectable
2yy8B-3oacB:
undetectable		 2yy8A-3oacB:
24.03
2yy8B-3oacB:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_F_SAMF228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 3oac GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Mentha
x
piperita) 		5 / 12 GLU B 181
TYR B 179
GLY B 146
ALA B 145
ALA B  76
 None
 1.37A 3nmuA-3oacB:
1.5
3nmuF-3oacB:
undetectable		 3nmuA-3oacB:
22.78
3nmuF-3oacB:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 3oac GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Mentha
x
piperita) 		5 / 11 GLU B 181
TYR B 179
GLY B 146
ALA B 145
ALA B  76
 None
 1.23A 3nmuB-3oacB:
undetectable
3nmuJ-3oacB:
undetectable		 3nmuB-3oacB:
22.78
3nmuJ-3oacB:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 3oac GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Mentha
x
piperita) 		5 / 12 GLU B 181
TYR B 179
GLY B 146
ALA B 145
ALA B  76
 None
 1.21A 3nvkF-3oacB:
2.3
3nvkJ-3oacB:
undetectable		 3nvkF-3oacB:
22.60
3nvkJ-3oacB:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3oac GERANYL DIPHOSPHATE
SYNTHASE SMALL
SUBUNIT
(Mentha
x
piperita) 		4 / 5 ALA B 188
ARG B 137
ALA B 196
GLU B 198
 None
 1.17A 5a06C-3oacB:
undetectable
5a06D-3oacB:
undetectable		 5a06C-3oacB:
22.93
5a06D-3oacB:
22.93