SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oad'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_2
(HIV-1 PROTEASE)		 3oad RENIN
(Homo
sapiens) 		5 / 11 LEU B 224
ASP B 226
GLY B 228
ALA B 229
PRO B 306
 None
 0.83A 1hxwB-3oadB:
4.6		 1hxwB-3oadB:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 3oad RENIN
(Homo
sapiens) 		4 / 8 LEU B 279
ALA B 299
ILE B 300
GLY B 316
 None
 0.78A 1sv9A-3oadB:
undetectable		 1sv9A-3oadB:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_1
(POL POLYPROTEIN)		 3oad RENIN
(Homo
sapiens) 		5 / 10 LEU B 224
ASP B 226
GLY B 228
ALA B 229
THR B 312
 None
 0.93A 1t7iA-3oadB:
undetectable		 1t7iA-3oadB:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 3oad RENIN
(Homo
sapiens) 		3 / 3 THR B 309
PRO B 311
PRO B 308
 None
 0.82A 2d55C-3oadB:
undetectable		 2d55C-3oadB:
6.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_B_CHDB701_0
(FERROCHELATASE)		 3oad RENIN
(Homo
sapiens) 		3 / 3 LYS B 197
GLY B 310
PRO B 311
 None
 1.00A 2hreB-3oadB:
undetectable		 2hreB-3oadB:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3oad RENIN
(Homo
sapiens) 		4 / 8 PHE B 270
TRP B 313
ALA B 314
LEU B 315
 None
 1.01A 2o01A-3oadB:
undetectable		 2o01A-3oadB:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 3oad RENIN
(Homo
sapiens) 		5 / 12 LEU B 216
LEU B 222
ALA B 223
GLN B 202
PHE B 270
 None
 1.16A 2oaxD-3oadB:
undetectable		 2oaxD-3oadB:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 3oad RENIN
(Homo
sapiens) 		5 / 12 LEU B 216
LEU B 222
ALA B 223
GLN B 202
PHE B 270
 None
 1.16A 2oaxE-3oadB:
undetectable		 2oaxE-3oadB:
21.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D91_A_REMA350_1
(RENIN)		 3oad RENIN
(Homo
sapiens) 		6 / 12 LEU B 224
ASP B 226
SER B 230
SER B 233
HIS B 301
ALA B 314
 None
 0.36A 3d91A-3oadB:
29.1		 3d91A-3oadB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D91_B_REMB350_1
(RENIN)		 3oad RENIN
(Homo
sapiens) 		6 / 12 LEU B 224
ASP B 226
ALA B 229
SER B 230
SER B 233
HIS B 301
 None
 0.37A 3d91B-3oadB:
28.1		 3d91B-3oadB:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_3
(HIV-1 PROTEASE)		 3oad RENIN
(Homo
sapiens) 		5 / 12 LEU B 224
ASP B 226
GLY B 228
ALA B 229
PRO B 306
 None
 0.80A 3k4vB-3oadB:
3.7		 3k4vB-3oadB:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 3oad RENIN
(Homo
sapiens) 		5 / 12 LEU B 224
ASP B 226
GLY B 228
ALA B 229
PRO B 306
 None
 0.78A 3ndtB-3oadB:
4.7		 3ndtB-3oadB:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 3oad RENIN
(Homo
sapiens) 		5 / 12 LEU B 224
ASP B 226
GLY B 228
ALA B 229
ILE B 305
 None
 0.65A 3s54A-3oadB:
5.2		 3s54A-3oadB:
25.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_1
(PROTEASE)		 3oad RENIN
(Homo
sapiens) 		5 / 12 LEU B 224
ASP B 226
GLY B 228
ALA B 229
PRO B 306
 None
 0.80A 3tl9A-3oadB:
4.9		 3tl9A-3oadB:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA802_1
(CATALASE-PEROXIDASE)		 3oad RENIN
(Homo
sapiens) 		4 / 8 LEU B 272
ILE B 193
ASN B 194
ILE B 196
 None
 0.89A 3wxoA-3oadB:
undetectable		 3wxoA-3oadB:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_2
(PROTEASE)		 3oad RENIN
(Homo
sapiens) 		5 / 10 LEU B 224
ASP B 226
GLY B 228
ALA B 229
THR B 312
 None
 0.87A 4njtB-3oadB:
5.3		 4njtB-3oadB:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_2
(PROTEASE)		 3oad RENIN
(Homo
sapiens) 		5 / 9 LEU B 224
ASP B 226
GLY B 228
ALA B 229
THR B 312
 None
 0.87A 4njtD-3oadB:
5.3		 4njtD-3oadB:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3oad RENIN
(Homo
sapiens) 		4 / 7 LEU B 246
PRO B 266
LEU B 298
TYR B 284
 None
 0.68A 4z4fA-3oadB:
undetectable		 4z4fA-3oadB:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 3oad RENIN
(Homo
sapiens) 		5 / 12 LEU B 224
ASP B 226
GLY B 228
ALA B 229
ILE B 305
 None
 0.62A 5e5jB-3oadB:
4.7		 5e5jB-3oadB:
25.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3oad RENIN
(Homo
sapiens) 		4 / 7 LEU B 246
PRO B 266
LEU B 298
TYR B 284
 None
 0.72A 5t7bA-3oadB:
undetectable		 5t7bA-3oadB:
10.67