SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oag'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_C_C41C1328_1
(RENIN)		 3oag RENIN
(Homo
sapiens) 		8 / 12 GLN A  19
VAL A  36
ASP A  38
GLY A  40
SER A  41
PRO A 118
PHE A 124
VAL A 127
 LPQ  A 167 ( 4.4A)
LPQ  A 167 ( 4.5A)
LPQ  A 167 (-2.8A)
LPQ  A 167 (-3.8A)
LPQ  A 167 ( 3.9A)
LPQ  A 167 ( 4.4A)
LPQ  A 167 (-4.6A)
LPQ  A 167 (-4.6A)
 0.50A 2v0zC-3oagA:
23.6		 2v0zC-3oagA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_O_C41O1327_1
(RENIN)		 3oag RENIN
(Homo
sapiens) 		8 / 12 GLN A  19
VAL A  36
ASP A  38
GLY A  40
ALA A 122
PHE A 124
VAL A 127
GLN A 135
 LPQ  A 167 ( 4.4A)
LPQ  A 167 ( 4.5A)
LPQ  A 167 (-2.8A)
LPQ  A 167 (-3.8A)
LPQ  A 167 (-3.6A)
LPQ  A 167 (-4.6A)
LPQ  A 167 (-4.6A)
None
 0.38A 2v0zO-3oagA:
23.7		 2v0zO-3oagA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_O_C41O1327_2
(RENIN)		 3oag RENIN
(Homo
sapiens) 		4 / 8 TYR A  20
SER A  41
PRO A 118
LEU A 121
 None
LPQ  A 167 ( 3.9A)
LPQ  A 167 ( 4.4A)
None
 0.61A 2v0zO-3oagA:
23.7		 2v0zO-3oagA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3oag RENIN
(Homo
sapiens) 		5 / 10 ILE A 143
ILE A 147
VAL A 152
LYS A   4
VAL A  10
 None
 1.33A 3em0A-3oagA:
undetectable		 3em0A-3oagA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3oag RENIN
(Homo
sapiens) 		5 / 12 GLY A  22
THR A  13
SER A   9
ILE A  24
THR A  98
 None
 1.09A 3iv6A-3oagA:
undetectable		 3iv6A-3oagA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMF_A_6U9A1301_1
(ION TRANSPORT
PROTEIN)		 3oag RENIN
(Homo
sapiens) 		4 / 6 THR A  32
GLY A  25
GLU A  23
ILE A 102
 None
 0.86A 5kmfA-3oagA:
undetectable
5kmfC-3oagA:
undetectable		 5kmfA-3oagA:
21.68
5kmfC-3oagA:
21.68