SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oam'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		 3oam 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Vibrio
cholerae) 		4 / 5 VAL A   6
ASN A  96
VAL A  82
ILE A  88
 None
 1.08A 1z2bC-3oamA:
undetectable		 1z2bC-3oamA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3oam 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Vibrio
cholerae) 		4 / 7 TYR A 187
GLY A  75
THR A  76
TYR A 195
 None
 0.97A 2g70A-3oamA:
undetectable		 2g70A-3oamA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3oam 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Vibrio
cholerae) 		4 / 7 TYR A 187
GLY A  75
THR A  76
TYR A 195
 None
 0.95A 2g70B-3oamA:
undetectable		 2g70B-3oamA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3oam 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Vibrio
cholerae) 		3 / 3 ASP A 165
ASN A 166
THR A 159
 None
 0.63A 2pymB-3oamA:
undetectable		 2pymB-3oamA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 3oam 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Vibrio
cholerae) 		3 / 3 ASP A 165
ASN A 166
THR A 159
 None
 0.78A 2q63B-3oamA:
undetectable		 2q63B-3oamA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 3oam 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Vibrio
cholerae) 		4 / 7 ILE A  93
ILE A 108
LEU A 126
ILE A 184
 None
 0.82A 2q83A-3oamA:
undetectable		 2q83A-3oamA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9W_A_ACTA170_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3oam 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Vibrio
cholerae) 		3 / 3 SER A  74
GLY A  75
THR A  76
 None
 0.24A 3k9wA-3oamA:
3.9		 3k9wA-3oamA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 3oam 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Vibrio
cholerae) 		3 / 3 LEU A 103
TRP A  32
GLY A  25
 None
 0.76A 3l35A-3oamA:
undetectable
3l35H-3oamA:
undetectable		 3l35A-3oamA:
9.68
3l35H-3oamA:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 3oam 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Vibrio
cholerae) 		3 / 3 LEU A 103
TRP A  32
GLY A  25
 None
 0.75A 3l35B-3oamA:
undetectable
3l35K-3oamA:
undetectable		 3l35B-3oamA:
9.68
3l35K-3oamA:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA409_0
(FAD:PROTEIN FMN
TRANSFERASE)		 3oam 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Vibrio
cholerae) 		4 / 5 VAL A  82
ILE A  88
VAL A   6
THR A   4
 None
 0.71A 4xdtA-3oamA:
undetectable		 4xdtA-3oamA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3oam 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Vibrio
cholerae) 		4 / 5 ALA A 124
THR A 125
TYR A 185
HIS A 222
 None
 1.29A 5ecmA-3oamA:
undetectable		 5ecmA-3oamA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HV1_A_RFPA902_1
(PHOSPHOENOLPYRUVATE
SYNTHASE)		 3oam 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Vibrio
cholerae) 		5 / 12 VAL A  58
GLN A  31
PRO A   8
ALA A   9
VAL A  54
 None
 1.15A 5hv1A-3oamA:
undetectable		 5hv1A-3oamA:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 3oam 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Vibrio
cholerae) 		5 / 12 PRO A 106
ILE A 109
ILE A 108
VAL A  97
ILE A 184
 None
 1.09A 6hlpA-3oamA:
2.6		 6hlpA-3oamA:
18.45