SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oaz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SU9_A_ACTA426_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
3oaz FAB 2G12, HEAVY
CHAIN

(Homo
sapiens)
3 / 3 GLN H   3
GLU H   1
LYS H   1
None
0.96A 3su9A-3oazH:
undetectable
3su9A-3oazH:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3oaz FAB 2G12, HEAVY
CHAIN

(Homo
sapiens)
5 / 11 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
None
0.89A 4qvnH-3oazH:
undetectable
4qvnI-3oazH:
undetectable
4qvnH-3oazH:
20.32
4qvnI-3oazH:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3oaz FAB 2G12, HEAVY
CHAIN

(Homo
sapiens)
5 / 10 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
None
0.89A 4qvnV-3oazH:
undetectable
4qvnW-3oazH:
undetectable
4qvnV-3oazH:
20.32
4qvnW-3oazH:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3oaz FAB 2G12, HEAVY
CHAIN

(Homo
sapiens)
5 / 12 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
None
0.87A 4qvpH-3oazH:
undetectable
4qvpI-3oazH:
undetectable
4qvpH-3oazH:
20.32
4qvpI-3oazH:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3oaz FAB 2G12, HEAVY
CHAIN

(Homo
sapiens)
5 / 12 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
None
0.87A 4qvpV-3oazH:
undetectable
4qvpW-3oazH:
undetectable
4qvpV-3oazH:
20.32
4qvpW-3oazH:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3oaz FAB 2G12, HEAVY
CHAIN

(Homo
sapiens)
5 / 11 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
None
0.88A 4qvqH-3oazH:
undetectable
4qvqI-3oazH:
undetectable
4qvqH-3oazH:
20.32
4qvqI-3oazH:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3oaz FAB 2G12, HEAVY
CHAIN

(Homo
sapiens)
5 / 11 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
None
0.87A 4qvqV-3oazH:
undetectable
4qvqW-3oazH:
undetectable
4qvqV-3oazH:
20.32
4qvqW-3oazH:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
3oaz FAB 2G12, HEAVY
CHAIN

(Homo
sapiens)
5 / 11 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
None
0.93A 4qvvH-3oazH:
undetectable
4qvvH-3oazH:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
3oaz FAB 2G12, HEAVY
CHAIN

(Homo
sapiens)
5 / 11 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
None
0.93A 4qvvV-3oazH:
undetectable
4qvvV-3oazH:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
3oaz FAB 2G12, HEAVY
CHAIN

(Homo
sapiens)
5 / 11 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
None
0.94A 4qvyH-3oazH:
undetectable
4qvyH-3oazH:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3oaz FAB 2G12, HEAVY
CHAIN

(Homo
sapiens)
5 / 12 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
None
0.94A 4qvyV-3oazH:
undetectable
4qvyW-3oazH:
undetectable
4qvyV-3oazH:
20.32
4qvyW-3oazH:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3oaz FAB 2G12, HEAVY
CHAIN

(Homo
sapiens)
5 / 11 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
None
0.92A 4qw0H-3oazH:
undetectable
4qw0I-3oazH:
undetectable
4qw0H-3oazH:
20.32
4qw0I-3oazH:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3oaz FAB 2G12, HEAVY
CHAIN

(Homo
sapiens)
5 / 11 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
None
0.92A 4qw0V-3oazH:
undetectable
4qw0W-3oazH:
undetectable
4qw0V-3oazH:
20.32
4qw0W-3oazH:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3oaz FAB 2G12, HEAVY
CHAIN

(Homo
sapiens)
5 / 12 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
None
0.92A 4qw1H-3oazH:
undetectable
4qw1I-3oazH:
undetectable
4qw1H-3oazH:
20.32
4qw1I-3oazH:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3oaz FAB 2G12, HEAVY
CHAIN

(Homo
sapiens)
5 / 12 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
None
0.92A 4qw1V-3oazH:
undetectable
4qw1W-3oazH:
undetectable
4qw1V-3oazH:
20.32
4qw1W-3oazH:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3oaz FAB 2G12, HEAVY
CHAIN

(Homo
sapiens)
5 / 11 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
None
0.92A 4qwuH-3oazH:
undetectable
4qwuI-3oazH:
undetectable
4qwuH-3oazH:
20.32
4qwuI-3oazH:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3oaz FAB 2G12, HEAVY
CHAIN

(Homo
sapiens)
5 / 11 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
None
0.92A 4qwuV-3oazH:
undetectable
4qwuW-3oazH:
undetectable
4qwuV-3oazH:
20.32
4qwuW-3oazH:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3oaz FAB 2G12, HEAVY
CHAIN

(Homo
sapiens)
5 / 11 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
None
0.91A 5bxnH-3oazH:
undetectable
5bxnI-3oazH:
undetectable
5bxnH-3oazH:
19.43
5bxnI-3oazH:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3oaz FAB 2G12, HEAVY
CHAIN

(Homo
sapiens)
5 / 12 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
None
0.90A 5cz7V-3oazH:
undetectable
5cz7W-3oazH:
undetectable
5cz7V-3oazH:
20.32
5cz7W-3oazH:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
3oaz FAB 2G12, HEAVY
CHAIN

(Homo
sapiens)
5 / 11 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
None
0.91A 5d0xV-3oazH:
undetectable
5d0xV-3oazH:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3oaz FAB 2G12, HEAVY
CHAIN

(Homo
sapiens)
5 / 12 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
None
0.87A 5l5fH-3oazH:
undetectable
5l5fI-3oazH:
undetectable
5l5fH-3oazH:
20.32
5l5fI-3oazH:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3oaz FAB 2G12, HEAVY
CHAIN

(Homo
sapiens)
5 / 12 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
None
0.88A 5l5fV-3oazH:
undetectable
5l5fW-3oazH:
undetectable
5l5fV-3oazH:
20.32
5l5fW-3oazH:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3oaz FAB 2G12, HEAVY
CHAIN

(Homo
sapiens)
5 / 12 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
None
0.92A 5l66H-3oazH:
undetectable
5l66I-3oazH:
undetectable
5l66H-3oazH:
20.32
5l66I-3oazH:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3oaz FAB 2G12, HEAVY
CHAIN

(Homo
sapiens)
5 / 12 SER H 197
GLY H 136
THR H 137
ALA H 138
THR H 133
None
0.93A 5l66V-3oazH:
undetectable
5l66W-3oazH:
undetectable
5l66V-3oazH:
20.32
5l66W-3oazH:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)
3oaz FAB 2G12, HEAVY
CHAIN

(Homo
sapiens)
6 / 12 VAL H 193
THR H 137
LEU H 166
VAL H 171
GLY H 169
VAL H 225
None
1.50A 6a94B-3oazH:
undetectable
6a94B-3oazH:
18.32