SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ob8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 7 TYR A 136
GLU A 130
PHE A 157
ARG A  19
 None
 1.26A 1b2iA-3ob8A:
undetectable		 1b2iA-3ob8A:
5.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 TRP A 804
VAL A 880
TRP A 789
 None
 1.20A 1c4dA-3ob8A:
undetectable
1c4dB-3ob8A:
undetectable		 1c4dA-3ob8A:
1.58
1c4dB-3ob8A:
1.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 5 ASP A 401
HIS A 471
HIS A 327
HIS A 326
 None
 1.24A 1ei6A-3ob8A:
undetectable		 1ei6A-3ob8A:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GEB_A_CAMA418_0
(CYTOCHROME P450-CAM)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 9 THR A 666
LEU A 685
VAL A 691
VAL A 700
ILE A 680
 None
 1.28A 1gebA-3ob8A:
undetectable		 1gebA-3ob8A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC1200_1
(PROTEIN (METHIONINE
REPRESSOR))		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 4 HIS A  72
ALA A 364
PHE A 361
GLY A 362
 None
 1.36A 1mj2D-3ob8A:
undetectable		 1mj2D-3ob8A:
7.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_2
(CARBONIC ANHYDRASE
II)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 4 HIS A  16
VAL A  15
THR A  22
LEU A 464
 None
 1.22A 1oq5A-3ob8A:
undetectable		 1oq5A-3ob8A:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_D_MTXD354_1
(PTERIDINE REDUCTASE
1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 12 ARG A 152
PRO A  12
LEU A 447
TYR A 453
TYR A  91
 None
 1.14A 1p33D-3ob8A:
undetectable		 1p33D-3ob8A:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_B_DIFB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 9 LEU A1006
LEU A 563
TYR A 566
GLY A 561
SER A 998
 None
 1.27A 1pxxB-3ob8A:
undetectable		 1pxxB-3ob8A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_B_RBFB596_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 11 VAL A 212
VAL A 230
GLU A 210
LEU A 313
ILE A 242
 None
 1.12A 1t6zB-3ob8A:
undetectable		 1t6zB-3ob8A:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB8_0
(GRAMICIDIN A)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 5 VAL A 352
GLY A 351
VAL A 385
TRP A 406
 None
 1.16A 1tkqB-3ob8A:
undetectable		 1tkqB-3ob8A:
1.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.67A 1v54A-3ob8A:
undetectable		 1v54A-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.68A 1v54N-3ob8A:
undetectable		 1v54N-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.67A 1v55A-3ob8A:
undetectable		 1v55A-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.65A 1v55N-3ob8A:
undetectable		 1v55N-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_C_CRNC4401_1
(CREATININE
AMIDOHYDROLASE)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 8 HIS A 975
ASP A 610
TYR A  86
TRP A 189
 MN  A3005 (-3.1A)
None
None
None
 0.93A 1v7zC-3ob8A:
undetectable		 1v7zC-3ob8A:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_D_CRND5401_1
(CREATININE
AMIDOHYDROLASE)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 8 HIS A 975
ASP A 610
TYR A  86
TRP A 189
 MN  A3005 (-3.1A)
None
None
None
 0.97A 1v7zD-3ob8A:
undetectable		 1v7zD-3ob8A:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_E_CRNE6401_1
(CREATININE
AMIDOHYDROLASE)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 8 HIS A 975
ASP A 610
TYR A  86
TRP A 189
 MN  A3005 (-3.1A)
None
None
None
 0.96A 1v7zE-3ob8A:
undetectable		 1v7zE-3ob8A:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_F_CRNF7401_1
(CREATININE
AMIDOHYDROLASE)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 8 HIS A 975
ASP A 610
TYR A  86
TRP A 189
 MN  A3005 (-3.1A)
None
None
None
 0.95A 1v7zF-3ob8A:
undetectable		 1v7zF-3ob8A:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 8 VAL A 328
ASP A 401
TYR A 309
LEU A 228
 None
 1.02A 1z2bB-3ob8A:
undetectable		 1z2bB-3ob8A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A7Q_A_CFBA328_2
(DEOXYCYTIDINE KINASE)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 4 ILE A 474
ASP A 398
LEU A 374
ARG A 331
 None
 1.49A 2a7qA-3ob8A:
undetectable		 2a7qA-3ob8A:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 12 LEU A 348
ILE A 347
PHE A 580
TYR A 639
GLU A 302
 None
 1.34A 2bxfB-3ob8A:
undetectable		 2bxfB-3ob8A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 7 ARG A 111
GLY A  37
SER A  34
GLU A  33
 None
 1.06A 2c8aD-3ob8A:
undetectable		 2c8aD-3ob8A:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.66A 2dyrA-3ob8A:
undetectable		 2dyrA-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.68A 2dyrN-3ob8A:
undetectable		 2dyrN-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.70A 2dysA-3ob8A:
undetectable		 2dysA-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.67A 2dysN-3ob8A:
undetectable		 2dysN-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.66A 2eijA-3ob8A:
undetectable		 2eijA-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.65A 2eijN-3ob8A:
undetectable		 2eijN-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.64A 2eikA-3ob8A:
undetectable		 2eikA-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.66A 2eikN-3ob8A:
undetectable		 2eikN-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.67A 2eilA-3ob8A:
undetectable		 2eilA-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.67A 2eilN-3ob8A:
undetectable		 2eilN-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.65A 2eimA-3ob8A:
undetectable		 2eimA-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.67A 2eimN-3ob8A:
undetectable		 2eimN-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.71A 2einA-3ob8A:
undetectable		 2einA-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 THR A  22
ASP A 409
SER A 473
 None
 0.71A 2nxeA-3ob8A:
undetectable		 2nxeA-3ob8A:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 THR A  22
ASP A 409
SER A 473
 None
 0.75A 2nxeB-3ob8A:
undetectable		 2nxeB-3ob8A:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 6 PHE A 893
PHE A 962
GLY A 901
GLY A 899
 None
 1.00A 2qr2A-3ob8A:
undetectable
2qr2B-3ob8A:
undetectable		 2qr2A-3ob8A:
13.30
2qr2B-3ob8A:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 5 GLY A 901
GLY A 899
PHE A 893
PHE A 962
 None
 0.97A 2qr2A-3ob8A:
undetectable
2qr2B-3ob8A:
undetectable		 2qr2A-3ob8A:
13.30
2qr2B-3ob8A:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1501_1
(CYTOCHROME P450 3A4)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 10 PHE A 788
ILE A 767
THR A 849
ILE A 777
GLY A 881
 None
 1.06A 2v0mA-3ob8A:
undetectable		 2v0mA-3ob8A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 TRP A 406
GLN A 577
TRP A 477
 None
 1.35A 2vqyA-3ob8A:
undetectable		 2vqyA-3ob8A:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_C_TOPC1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 10 ILE A 347
ALA A 384
ILE A 475
SER A 520
ILE A 518
 None
 1.15A 2w9sC-3ob8A:
undetectable		 2w9sC-3ob8A:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.65A 2y69A-3ob8A:
undetectable		 2y69A-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.60A 2y69N-3ob8A:
undetectable		 2y69N-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.70A 2zxwA-3ob8A:
undetectable		 2zxwA-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.65A 2zxwN-3ob8A:
undetectable		 2zxwN-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.69A 3abkA-3ob8A:
undetectable		 3abkA-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.65A 3abkN-3ob8A:
undetectable		 3abkN-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.71A 3ablA-3ob8A:
undetectable		 3ablA-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.70A 3ablN-3ob8A:
undetectable		 3ablN-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.68A 3abmA-3ob8A:
undetectable		 3abmA-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.62A 3abmN-3ob8A:
undetectable		 3abmN-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.62A 3ag1A-3ob8A:
undetectable		 3ag1A-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.59A 3ag1N-3ob8A:
undetectable		 3ag1N-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.69A 3ag2A-3ob8A:
undetectable		 3ag2A-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.68A 3ag2N-3ob8A:
undetectable		 3ag2N-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.65A 3ag3A-3ob8A:
undetectable		 3ag3A-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.65A 3ag3N-3ob8A:
undetectable		 3ag3N-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.64A 3ag4A-3ob8A:
undetectable		 3ag4A-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.59A 3ag4N-3ob8A:
undetectable		 3ag4N-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.62A 3asnA-3ob8A:
undetectable		 3asnA-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.65A 3asnN-3ob8A:
undetectable		 3asnN-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.61A 3asoA-3ob8A:
undetectable		 3asoA-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.65A 3asoN-3ob8A:
undetectable		 3asoN-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_A_SHHA301_1
(HISTONE DEACETYLASE
7A)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 5 HIS A 327
HIS A 326
ASP A 401
HIS A 471
 None
 0.99A 3c0zA-3ob8A:
undetectable		 3c0zA-3ob8A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_C_SHHC301_1
(HISTONE DEACETYLASE
7A)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 6 HIS A 327
HIS A 326
ASP A 401
HIS A 471
 None
 1.00A 3c0zC-3ob8A:
undetectable		 3c0zC-3ob8A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.64A 3dtuA-3ob8A:
undetectable		 3dtuA-3ob8A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_CUC569_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.63A 3dtuC-3ob8A:
undetectable		 3dtuC-3ob8A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 GLU A 482
GLU A 414
TRP A 582
 MG  A3001 ( 3.1A)
MG  A3001 (-2.8A)
GAL  A2001 (-4.0A)
 1.15A 3hrdA-3ob8A:
undetectable
3hrdE-3ob8A:
undetectable
3hrdF-3ob8A:
undetectable		 3hrdA-3ob8A:
18.41
3hrdE-3ob8A:
18.41
3hrdF-3ob8A:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MYU_A_VIBA500_1
(HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 10 HIS A 355
ASN A 134
ASP A 412
TYR A 195
ASP A 133
 None
 1.44A 3myuA-3ob8A:
undetectable		 3myuA-3ob8A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUG_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 12 HIS A 630
VAL A 371
ASP A 373
ALA A 585
ARG A 354
 None
 1.10A 3sugA-3ob8A:
undetectable		 3sugA-3ob8A:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEG_A_DAHA416_1
(PHENYLALANYL-TRNA
SYNTHETASE,
MITOCHONDRIAL)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 12 ARG A 790
GLY A 561
GLY A 553
ALA A 555
GLY A 559
 None
 1.17A 3tegA-3ob8A:
undetectable		 3tegA-3ob8A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.66A 3wg7A-3ob8A:
undetectable		 3wg7A-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.70A 3wg7N-3ob8A:
undetectable		 3wg7N-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_A_CUA604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.69A 3x2qA-3ob8A:
undetectable		 3x2qA-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.62A 3x2qN-3ob8A:
undetectable		 3x2qN-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 ASP A 675
LYS A 674
ASP A 673
 None
 0.78A 4a7tA-3ob8A:
4.5		 4a7tA-3ob8A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_A_DM2A1106_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 11 SER A 785
PHE A 884
ASN A 861
LEU A 862
ALA A 830
 None
 1.20A 4dx7A-3ob8A:
undetectable		 4dx7A-3ob8A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_A_NCTA501_1
(CYTOCHROME P450 2A6)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 7 PHE A 129
ASN A 148
GLY A 146
ILE A 159
 None
 0.85A 4ejjA-3ob8A:
undetectable		 4ejjA-3ob8A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 8 ASP A 187
ASP A 623
CYH A1001
GLU A 583
 NA  A3006 ( 3.1A)
NA  A3006 ( 3.0A)
GAL  A2001 ( 4.4A)
None
 1.22A 4fewD-3ob8A:
undetectable		 4fewD-3ob8A:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 8 ASP A 187
ASP A 623
CYH A1001
GLU A 583
 NA  A3006 ( 3.1A)
NA  A3006 ( 3.0A)
GAL  A2001 ( 4.4A)
None
 1.21A 4fewF-3ob8A:
undetectable		 4fewF-3ob8A:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 6 PHE A 279
ILE A 277
PHE A 244
PHE A 289
 None
 1.27A 4fgkA-3ob8A:
undetectable		 4fgkA-3ob8A:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIM_A_CELA711_1
(LACTOTRANSFERRIN)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 9 GLU A 999
GLY A 997
VAL A 996
PRO A 560
GLU A 583
 None
 1.42A 4fimA-3ob8A:
undetectable		 4fimA-3ob8A:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUB_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 TYR A 507
ARG A 386
HIS A 389
 None
None
GAL  A2001 (-3.8A)
 1.02A 4fubA-3ob8A:
undetectable		 4fubA-3ob8A:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HXY_B_ACAB502_1
(PLM1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 7 VAL A 163
SER A 119
GLN A 160
LEU A 200
 None
 1.17A 4hxyB-3ob8A:
undetectable		 4hxyB-3ob8A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 7 TYR A 890
ILE A 943
GLY A 949
PHE A 945
 None
 0.83A 4iqqA-3ob8A:
undetectable		 4iqqA-3ob8A:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_D_SVRD301_1
(NUCLEOCAPSID PROTEIN)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 11 GLY A 933
ASN A 934
ARG A 879
PHE A 893
ILE A 964
 None
 1.31A 4j4vD-3ob8A:
undetectable
4j4vE-3ob8A:
undetectable		 4j4vD-3ob8A:
13.00
4j4vE-3ob8A:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 12 ASP A 906
ALA A 555
SER A 562
GLY A 553
THR A 793
 None
 1.30A 4mm4A-3ob8A:
undetectable		 4mm4A-3ob8A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_1
(NEURAMINIDASE)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 ARG A 196
ASP A 356
ARG A 467
 None
 0.81A 4mx0A-3ob8A:
undetectable		 4mx0A-3ob8A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_1
(NEURAMINIDASE)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 ARG A 467
ASP A 409
ARG A 196
 None
 0.95A 4mx0A-3ob8A:
undetectable		 4mx0A-3ob8A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 5 ASN A 339
PRO A 546
GLY A 338
ASP A 434
 None
 1.13A 4n48B-3ob8A:
undetectable		 4n48B-3ob8A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 12 HIS A 471
HIS A 326
HIS A 327
ASP A 401
SER A 473
 None
 1.36A 4r88A-3ob8A:
6.3		 4r88A-3ob8A:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 12 HIS A 647
LEU A 348
GLN A 567
ILE A 643
GLU A 688
 None
 1.33A 4r88A-3ob8A:
6.3		 4r88A-3ob8A:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 12 HIS A 647
LEU A 348
GLN A 567
ILE A 643
GLU A 688
 None
 1.33A 4r88B-3ob8A:
6.3		 4r88B-3ob8A:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 12 HIS A 647
LEU A 348
GLN A 567
ILE A 643
GLU A 688
 None
 1.34A 4r88C-3ob8A:
3.4		 4r88C-3ob8A:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 12 HIS A 647
LEU A 348
GLN A 567
ILE A 643
GLU A 688
 None
 1.33A 4r88D-3ob8A:
6.3		 4r88D-3ob8A:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 12 HIS A 647
LEU A 348
GLN A 567
ILE A 643
GLU A 688
 None
 1.35A 4r88E-3ob8A:
6.2		 4r88E-3ob8A:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 12 HIS A 647
LEU A 348
GLN A 567
ILE A 643
GLU A 688
 None
 1.36A 4r88F-3ob8A:
4.7		 4r88F-3ob8A:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 5 TYR A 523
PRO A1003
LEU A 549
TYR A 566
 None
 1.47A 4w5qA-3ob8A:
undetectable		 4w5qA-3ob8A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 7 VAL A 418
ILE A  97
HIS A 489
LEU A 413
 None
 1.03A 4xo7B-3ob8A:
8.9		 4xo7B-3ob8A:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z3O_F_MFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT
B,PARE30-PARC55
FUSED TOPO IV FROM
S. PNEUMONIAE
E-SITE DNA)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 5 ARG A 460
GLY A 154
GLU A 130
SER A 180
 None
 1.12A 4z3oA-3ob8A:
undetectable
4z3oB-3ob8A:
undetectable		 4z3oA-3ob8A:
21.96
4z3oB-3ob8A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 6 TYR A 523
PRO A1003
LEU A 549
TYR A 566
 None
 1.37A 4z4cA-3ob8A:
1.7		 4z4cA-3ob8A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 6 LEU A 549
TYR A 523
PRO A 524
TYR A 566
 None
 1.28A 4z4gA-3ob8A:
undetectable		 4z4gA-3ob8A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.66A 5b1aA-3ob8A:
undetectable		 5b1aA-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.70A 5b1aN-3ob8A:
undetectable		 5b1aN-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.67A 5b1bA-3ob8A:
undetectable		 5b1bA-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.69A 5b1bN-3ob8A:
undetectable		 5b1bN-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.69A 5b3sA-3ob8A:
undetectable		 5b3sA-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.72A 5b3sN-3ob8A:
undetectable		 5b3sN-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 7 HIS A 357
ASP A 610
TYR A  86
HIS A 358
 None
 1.47A 5b3sN-3ob8A:
undetectable
5b3sP-3ob8A:
undetectable		 5b3sN-3ob8A:
18.19
5b3sP-3ob8A:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 12 GLY A 480
THR A 181
TYR A 457
VAL A  15
HIS A 489
 None
 1.23A 5d0yA-3ob8A:
undetectable		 5d0yA-3ob8A:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 12 TYR A 853
PHE A 877
ILE A 809
GLY A 846
MET A 866
 None
 1.27A 5esgA-3ob8A:
undetectable		 5esgA-3ob8A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWY_E_010E6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 4 THR A 415
LEU A 413
HIS A 489
GLY A 480
 None
 1.27A 5gwyA-3ob8A:
undetectable		 5gwyA-3ob8A:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 10 VAL A 352
ILE A 581
TYR A 552
LEU A 563
ILE A 340
 None
 1.32A 5hw8C-3ob8A:
undetectable
5hw8H-3ob8A:
undetectable		 5hw8C-3ob8A:
8.28
5hw8H-3ob8A:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.67A 5iy5A-3ob8A:
undetectable		 5iy5A-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.66A 5iy5N-3ob8A:
undetectable		 5iy5N-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZF_E_AZ1E2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
6J9-ZEU-DAR-ACA-DAR-
NH2)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 7 GLY A 933
SER A 918
LEU A 941
GLU A 967
 None
 0.79A 5izfA-3ob8A:
undetectable		 5izfA-3ob8A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 10 ILE A 648
ILE A 657
VAL A 700
THR A 697
ILE A 680
 None
 1.22A 5lg3F-3ob8A:
undetectable		 5lg3F-3ob8A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 10 ILE A 648
ILE A 657
VAL A 700
THR A 697
ILE A 680
 None
 1.23A 5lg3G-3ob8A:
undetectable		 5lg3G-3ob8A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_H_Z80H401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 10 ILE A 648
ILE A 657
VAL A 700
THR A 697
ILE A 680
 None
 1.22A 5lg3H-3ob8A:
undetectable		 5lg3H-3ob8A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 12 ILE A 648
ILE A 657
VAL A 700
THR A 697
ILE A 680
 None
 1.19A 5lg3J-3ob8A:
undetectable		 5lg3J-3ob8A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 7 TYR A 890
ILE A 943
GLY A 949
PHE A 945
 None
 0.88A 5nooA-3ob8A:
undetectable		 5nooA-3ob8A:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 4 VAL A 174
LEU A  43
ASN A 134
ASP A 133
 None
 1.30A 5vcyA-3ob8A:
undetectable		 5vcyA-3ob8A:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.62A 5w97a-3ob8A:
undetectable		 5w97a-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.67A 5waua-3ob8A:
undetectable		 5waua-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.66A 5x19A-3ob8A:
undetectable		 5x19A-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.69A 5x19N-3ob8A:
undetectable		 5x19N-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.68A 5x1bA-3ob8A:
undetectable		 5x1bA-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.68A 5x1bN-3ob8A:
undetectable		 5x1bN-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.62A 5x1fA-3ob8A:
undetectable		 5x1fA-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.64A 5x1fN-3ob8A:
undetectable		 5x1fN-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.65A 5xdqA-3ob8A:
undetectable		 5xdqA-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.65A 5xdqN-3ob8A:
undetectable		 5xdqN-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.65A 5xdxA-3ob8A:
undetectable		 5xdxA-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.63A 5xdxN-3ob8A:
undetectable		 5xdxN-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_B_BEZB201_0
(NS3 PROTEASE)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 5 HIS A 602
ALA A 597
SER A 595
GLY A 599
 None
 1.25A 5yodB-3ob8A:
undetectable		 5yodB-3ob8A:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.68A 5z84A-3ob8A:
undetectable		 5z84A-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.69A 5z84N-3ob8A:
undetectable		 5z84N-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.69A 5z85A-3ob8A:
undetectable		 5z85A-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.70A 5z85N-3ob8A:
undetectable		 5z85N-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.62A 5z86A-3ob8A:
undetectable		 5z86A-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.65A 5z86N-3ob8A:
undetectable		 5z86N-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.67A 5zcoA-3ob8A:
undetectable		 5zcoA-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.67A 5zcoN-3ob8A:
undetectable		 5zcoN-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.66A 5zcpA-3ob8A:
undetectable		 5zcpA-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.69A 5zcpN-3ob8A:
undetectable		 5zcpN-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.67A 5zcqA-3ob8A:
undetectable		 5zcqA-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.68A 5zcqN-3ob8A:
undetectable		 5zcqN-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA609_0
(ALPHA-AMYLASE)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 7 LYS A 641
GLY A 720
ASP A 675
TYR A 699
 None
 1.40A 6ag0A-3ob8A:
8.6		 6ag0A-3ob8A:
5.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 12 GLU A 689
VAL A 700
PHE A 671
PRO A 694
ILE A 680
 None
 1.31A 6becA-3ob8A:
4.1
6becB-3ob8A:
undetectable
6becC-3ob8A:
3.9		 6becA-3ob8A:
20.50
6becB-3ob8A:
20.50
6becC-3ob8A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_B_SAMB901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 12 LEU A 549
GLY A 579
VAL A 342
ILE A 347
ASP A 662
 None
 1.23A 6bxnB-3ob8A:
undetectable		 6bxnB-3ob8A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FTP_B_DM2B501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 9 LEU A 547
SER A 520
PHE A 521
GLU A 508
LEU A 511
 None
 1.17A 6ftpA-3ob8A:
undetectable
6ftpB-3ob8A:
undetectable		 6ftpA-3ob8A:
6.66
6ftpB-3ob8A:
5.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.66A 6hu9a-3ob8A:
undetectable		 6hu9a-3ob8A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.73A 6hu9m-3ob8A:
undetectable		 6hu9m-3ob8A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I0Y_A_TRPA3001_0
(23S RIBOSOMAL RNA
TRYPTOPHANASE OPERON
LEADER PEPTIDE)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 TRP A 477
ILE A 408
ASP A 409
 None
 0.57A 6i0y7-3ob8A:
undetectable		 6i0y7-3ob8A:
2.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_F_AM2F301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		4 / 7 TRP A 582
HIS A 389
GLU A 414
GLU A 431
 GAL  A2001 (-4.0A)
GAL  A2001 (-3.8A)
MG  A3001 (-2.8A)
None
 1.40A 6mn4F-3ob8A:
undetectable		 6mn4F-3ob8A:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_0
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		5 / 12 VAL A 328
ASP A 312
PHE A 244
ILE A 209
TYR A  26
 None
 1.48A 6mxtA-3ob8A:
undetectable		 6mxtA-3ob8A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.70A 6nknA-3ob8A:
undetectable		 6nknA-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.70A 6nknN-3ob8A:
undetectable		 6nknN-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.66A 6nmfA-3ob8A:
undetectable		 6nmfA-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.61A 6nmfN-3ob8A:
undetectable		 6nmfN-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.62A 6nmpA-3ob8A:
undetectable		 6nmpA-3ob8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ob8 BETA-GALACTOSIDASE
(Kluyveromyces
lactis) 		3 / 3 HIS A 471
HIS A 326
HIS A 327
 None
 0.63A 6nmpN-3ob8A:
undetectable		 6nmpN-3ob8A:
18.19