SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3obe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3obe SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		3 / 3 ASP A 243
HIS A 196
HIS A 194
 None
PO4  A 400 (-3.8A)
PO4  A 400 (-4.5A)
 0.65A 1oe1A-3obeA:
undetectable		 1oe1A-3obeA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3obe SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		3 / 3 ASP A 243
HIS A 196
HIS A 194
 None
PO4  A 400 (-3.8A)
PO4  A 400 (-4.5A)
 0.65A 1oe3A-3obeA:
undetectable		 1oe3A-3obeA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3obe SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		3 / 3 ASP A 243
HIS A 196
HIS A 194
 None
PO4  A 400 (-3.8A)
PO4  A 400 (-4.5A)
 0.66A 2xxgA-3obeA:
undetectable		 2xxgA-3obeA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3obe SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		3 / 3 ASP A 243
HIS A 196
HIS A 194
 None
PO4  A 400 (-3.8A)
PO4  A 400 (-4.5A)
 0.66A 2xxgC-3obeA:
undetectable		 2xxgC-3obeA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 3obe SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		3 / 3 MET A 249
GLU A 304
ASP A 306
 None
 0.94A 3a25A-3obeA:
undetectable		 3a25A-3obeA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 3obe SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 7 GLY A  66
ASN A  65
ALA A 113
ALA A  71
 None
 0.80A 3a2qA-3obeA:
undetectable		 3a2qA-3obeA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZ0_B_CLYB900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 3obe SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 8 TYR A 261
TYR A 224
PHE A 265
ILE A 294
 None
 0.96A 3jz0B-3obeA:
undetectable		 3jz0B-3obeA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 3obe SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 4 GLY A 298
TYR A 300
GLY A  49
ASP A  77
 EOH  A 402 (-3.4A)
EOH  A 402 (-4.0A)
EOH  A 402 (-4.2A)
EOH  A 402 (-3.8A)
 1.09A 3kl3A-3obeA:
11.4		 3kl3A-3obeA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_C_FLPC701_1
(CYCLOOXYGENASE-2)		 3obe SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		6 / 12 VAL A 329
VAL A 301
LEU A  50
ALA A 320
SER A 319
LEU A 323
 None
 1.50A 3pghC-3obeA:
undetectable		 3pghC-3obeA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG8_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3obe SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		3 / 3 TYR A 193
GLU A 227
TYR A 224
 None
 1.01A 3ug8A-3obeA:
9.5		 3ug8A-3obeA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_0U9A601_1
(CHOLESTEROL
24-HYDROXYLASE)		 3obe SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		5 / 12 PHE A  90
LEU A 122
ALA A 180
ALA A 144
THR A 145
 None
 1.14A 4fiaA-3obeA:
undetectable		 4fiaA-3obeA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_198A602_1
(CHOLESTEROL
24-HYDROXYLASE)		 3obe SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		5 / 12 PHE A  90
LEU A 122
ALA A 180
ALA A 144
THR A 145
 None
 1.14A 4fiaA-3obeA:
undetectable		 4fiaA-3obeA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M51_A_BEZA501_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 3obe SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 6 ILE A 147
ILE A 189
PHE A  90
LEU A 122
 None
 0.94A 4m51A-3obeA:
7.1		 4m51A-3obeA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRY_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 3obe SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 8 GLY A  56
GLN A  57
TYR A  93
PHE A  81
 EOH  A 405 ( 4.7A)
None
None
EOH  A 406 (-3.9A)
 1.03A 4wryA-3obeA:
undetectable		 4wryA-3obeA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRZ_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 3obe SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 8 GLY A  56
GLN A  57
TYR A  93
PHE A  81
 EOH  A 405 ( 4.7A)
None
None
EOH  A 406 (-3.9A)
 1.03A 4wrzA-3obeA:
undetectable		 4wrzA-3obeA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3obe SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 7 PHE A 137
GLU A 175
SER A 174
VAL A 172
 None
 1.44A 5fj3A-3obeA:
undetectable
5fj3B-3obeA:
1.4		 5fj3A-3obeA:
19.78
5fj3B-3obeA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3obe SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		3 / 3 VAL A 153
SER A 103
MET A 109
 None
 0.83A 5ikqA-3obeA:
undetectable		 5ikqA-3obeA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_D_SAMD501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3obe SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		5 / 10 LEU A 268
ILE A 296
GLY A 298
VAL A 329
ALA A 291
 None
None
EOH  A 402 (-3.4A)
None
None
 1.03A 5o96C-3obeA:
undetectable
5o96D-3obeA:
undetectable		 5o96C-3obeA:
24.63
5o96D-3obeA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3obe SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 7 PHE A 137
GLU A 175
SER A 174
VAL A 172
 None
 1.44A 5vvnA-3obeA:
undetectable
5vvnB-3obeA:
undetectable		 5vvnA-3obeA:
19.78
5vvnB-3obeA:
19.78