SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3obf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 3obf PUTATIVE
TRANSCRIPTIONAL
REGULATOR, ICLR
FAMILY
(Paenarthrobacter
aurescens) 		3 / 3 LEU A 193
SER A 188
ASN A 238
 None
 0.65A 1bx4A-3obfA:
undetectable		 1bx4A-3obfA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3obf PUTATIVE
TRANSCRIPTIONAL
REGULATOR, ICLR
FAMILY
(Paenarthrobacter
aurescens) 		4 / 7 ALA A 262
ARG A 132
ASN A 127
GLU A 163
 None
 1.34A 1t9wA-3obfA:
undetectable		 1t9wA-3obfA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3obf PUTATIVE
TRANSCRIPTIONAL
REGULATOR, ICLR
FAMILY
(Paenarthrobacter
aurescens) 		3 / 3 GLU A 241
GLU A 183
LEU A 193
 None
 0.72A 1v8bA-3obfA:
undetectable		 1v8bA-3obfA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_A_DVAA35_0
(UBIQUITIN)		 3obf PUTATIVE
TRANSCRIPTIONAL
REGULATOR, ICLR
FAMILY
(Paenarthrobacter
aurescens) 		4 / 4 GLN A 164
GLU A 163
ILE A 165
PRO A 166
 None
 1.03A 2fcnA-3obfA:
undetectable		 2fcnA-3obfA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1008_1
(SERUM ALBUMIN)		 3obf PUTATIVE
TRANSCRIPTIONAL
REGULATOR, ICLR
FAMILY
(Paenarthrobacter
aurescens) 		5 / 9 SER A 149
ALA A 284
VAL A 292
LEU A 138
VAL A 137
 None
 1.49A 4z69A-3obfA:
undetectable		 4z69A-3obfA:
14.78