SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3obv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3obv PROTEIN DIAPHANOUS
HOMOLOG 1
(Mus
musculus) 		4 / 7 PHE E1069
ALA E 922
ILE E 861
ILE E 874
 None
 0.96A 1oniD-3obvE:
undetectable
1oniF-3obvE:
undetectable		 1oniD-3obvE:
15.24
1oniF-3obvE:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_1
(N,N-DIMETHYLGLYCINE
OXIDASE)		 3obv PROTEIN DIAPHANOUS
HOMOLOG 1
(Mus
musculus) 		3 / 3 ASP E 992
THR E1001
GLU E1134
 None
 0.80A 1pj7A-3obvE:
undetectable		 1pj7A-3obvE:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7J_A_TESA203_1
(ANDROGEN RECEPTOR)		 3obv PROTEIN DIAPHANOUS
HOMOLOG 1
(Mus
musculus) 		5 / 12 LEU E 869
ASN E 865
LEU E 862
MET E 910
MET E 873
 None
 1.34A 2q7jA-3obvE:
undetectable		 2q7jA-3obvE:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 3obv PROTEIN DIAPHANOUS
HOMOLOG 1
(Mus
musculus) 		5 / 11 LEU E 916
ILE E 861
PHE E1059
ASP E1064
ASP E1067
 None
 1.24A 2qeiA-3obvE:
undetectable		 2qeiA-3obvE:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3obv PROTEIN DIAPHANOUS
HOMOLOG 1
(Mus
musculus) 		5 / 9 LEU E 962
THR E 963
PHE E 986
GLY E 981
ALA E 979
 None
 1.41A 3jusB-3obvE:
undetectable		 3jusB-3obvE:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_D_CLMD221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3obv PROTEIN DIAPHANOUS
HOMOLOG 1
(Mus
musculus) 		5 / 12 PHE E1124
LEU E 962
VAL E 966
ALA E1007
CYH E1010
 None
 1.15A 3u9fD-3obvE:
undetectable
3u9fE-3obvE:
undetectable		 3u9fD-3obvE:
19.05
3u9fE-3obvE:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WAN_C_ACTC303_0
(BRANCHPOINT-BRIDGING
PROTEIN)		 3obv PROTEIN DIAPHANOUS
HOMOLOG 1
(Mus
musculus) 		3 / 3 ASP E1064
ARG E 919
PRO E 914
 None
 1.08A 4wanC-3obvE:
undetectable		 4wanC-3obvE:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB202_0
(HYDROXYNITRILE LYASE)		 3obv PROTEIN DIAPHANOUS
HOMOLOG 1
(Mus
musculus) 		4 / 7 THR E 993
MET E 970
VAL E 966
THR E 963
 None
 0.94A 5e4dA-3obvE:
undetectable
5e4dB-3obvE:
undetectable		 5e4dA-3obvE:
17.90
5e4dB-3obvE:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 3obv PROTEIN DIAPHANOUS
HOMOLOG 1
(Mus
musculus) 		3 / 3 ASN E 955
SER E 958
SER E 957
 None
 0.71A 5gsnA-3obvE:
undetectable		 5gsnA-3obvE:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3obv PROTEIN DIAPHANOUS
HOMOLOG 1
(Mus
musculus) 		3 / 3 CYH E 988
MET E1127
ASN E1126
 None
 1.23A 5qh8A-3obvE:
undetectable		 5qh8A-3obvE:
18.26