SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3obz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_C_THAC3_1
(LIVER
CARBOXYLESTERASE I)		 3obz PHYTANOYL-COA
DIOXYGENASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 LEU A  20
SER A 129
LEU A 132
LEU A 171
LEU A  18
 None
 0.91A 1mx1C-3obzA:
undetectable		 1mx1C-3obzA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 3obz PHYTANOYL-COA
DIOXYGENASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 7 GLY A  37
GLN A 258
ILE A  39
VAL A  40
 None
 1.07A 1rxcC-3obzA:
undetectable		 1rxcC-3obzA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 3obz PHYTANOYL-COA
DIOXYGENASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 8 GLY A  37
GLN A 258
ILE A  39
VAL A  40
 None
 0.99A 1rxcE-3obzA:
undetectable		 1rxcE-3obzA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 3obz PHYTANOYL-COA
DIOXYGENASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 7 GLY A  37
GLN A 258
ILE A  39
VAL A  40
 None
 1.00A 1rxcF-3obzA:
undetectable		 1rxcF-3obzA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 3obz PHYTANOYL-COA
DIOXYGENASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 7 GLY A  37
GLN A 258
ILE A  39
VAL A  40
 None
 1.03A 1rxcL-3obzA:
undetectable		 1rxcL-3obzA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_A_BEZA500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 3obz PHYTANOYL-COA
DIOXYGENASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 10 HIS A 263
ASP A 158
HIS A 156
SER A 248
LEU A 187
 AKG  A 481 ( 4.8A)
FE2  A 482 ( 2.6A)
FE2  A 482 ( 3.4A)
AKG  A 481 (-2.5A)
None
 1.34A 2q0jA-3obzA:
undetectable		 2q0jA-3obzA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN7_A_T44A1355_1
(THYROXINE-BINDING
GLOBULIN)		 3obz PHYTANOYL-COA
DIOXYGENASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 10 LEU A 237
LEU A 239
SER A   5
LEU A   4
LEU A  20
 None
 0.98A 2xn7A-3obzA:
undetectable
2xn7B-3obzA:
undetectable		 2xn7A-3obzA:
20.72
2xn7B-3obzA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		 3obz PHYTANOYL-COA
DIOXYGENASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 7 HIS A 110
THR A 281
LEU A 284
TRP A 277
 None
 1.15A 3arrA-3obzA:
undetectable		 3arrA-3obzA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 3obz PHYTANOYL-COA
DIOXYGENASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 6 GLY A  37
GLN A 258
ILE A  39
VAL A  40
 None
 1.01A 3kvvA-3obzA:
undetectable		 3kvvA-3obzA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 3obz PHYTANOYL-COA
DIOXYGENASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 6 GLY A  37
GLN A 258
ILE A  39
VAL A  40
 None
 1.01A 3kvvB-3obzA:
undetectable		 3kvvB-3obzA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 3obz PHYTANOYL-COA
DIOXYGENASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 6 GLY A  37
GLN A 258
ILE A  39
VAL A  40
 None
 1.03A 3kvvC-3obzA:
undetectable		 3kvvC-3obzA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 3obz PHYTANOYL-COA
DIOXYGENASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 6 GLY A  37
GLN A 258
ILE A  39
VAL A  40
 None
 1.03A 3kvvD-3obzA:
undetectable		 3kvvD-3obzA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 3obz PHYTANOYL-COA
DIOXYGENASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 6 GLY A  37
GLN A 258
ILE A  39
VAL A  40
 None
 1.02A 3kvvE-3obzA:
undetectable		 3kvvE-3obzA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 3obz PHYTANOYL-COA
DIOXYGENASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 6 GLY A  37
GLN A 258
ILE A  39
VAL A  40
 None
 1.00A 3kvvF-3obzA:
undetectable		 3kvvF-3obzA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3obz PHYTANOYL-COA
DIOXYGENASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		6 / 12 LEU A 278
ALA A 106
GLY A 104
GLY A  74
SER A  73
LEU A 284
 None
 1.49A 3ou6A-3obzA:
undetectable		 3ou6A-3obzA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3obz PHYTANOYL-COA
DIOXYGENASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 LEU A 278
GLY A 104
GLY A  74
SER A  73
HIS A 263
 None
None
None
None
AKG  A 481 ( 4.8A)
 1.14A 3ou7B-3obzA:
undetectable		 3ou7B-3obzA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 3obz PHYTANOYL-COA
DIOXYGENASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 GLN A 258
PHE A 144
TYR A 142
 None
 0.95A 3ucjB-3obzA:
undetectable		 3ucjB-3obzA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 3obz PHYTANOYL-COA
DIOXYGENASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 7 GLY A  37
GLN A 258
ILE A  39
VAL A  40
 None
 0.99A 4e1vB-3obzA:
undetectable		 4e1vB-3obzA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 3obz PHYTANOYL-COA
DIOXYGENASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 6 GLY A  37
GLN A 258
ILE A  39
VAL A  40
 None
 1.06A 4e1vF-3obzA:
undetectable		 4e1vF-3obzA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I90_A_ACTA500_0
(1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE)		 3obz PHYTANOYL-COA
DIOXYGENASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 LYS A 145
ARG A 257
TRP A 174
 AKG  A 481 (-4.1A)
AKG  A 481 (-2.7A)
AKG  A 481 (-4.2A)
 1.33A 4i90A-3obzA:
undetectable		 4i90A-3obzA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 3obz PHYTANOYL-COA
DIOXYGENASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 4 HIS A 156
GLU A 243
HIS A 241
LEU A 264
 FE2  A 482 ( 3.4A)
None
None
None
 1.41A 4m2rA-3obzA:
undetectable		 4m2rA-3obzA:
21.38