SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oc5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KVL_A_CLSA371_1
(BETA-LACTAMASE)		 3oc5 TOXIN COREGULATED
PILUS BIOSYNTHESIS
PROTEIN F
(Vibrio
cholerae) 		5 / 10 LEU A 127
TYR A 121
ASN A  46
THR A 176
GLY A 175
 None
 1.27A 1kvlA-3oc5A:
undetectable		 1kvlA-3oc5A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBC_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 3oc5 TOXIN COREGULATED
PILUS BIOSYNTHESIS
PROTEIN F
(Vibrio
cholerae) 		5 / 10 VAL A 168
LEU A 118
TYR A 135
LEU A 127
ALA A 166
 None
 1.36A 1pbcA-3oc5A:
undetectable		 1pbcA-3oc5A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_1
(DNA TOPOISOMERASE II)		 3oc5 TOXIN COREGULATED
PILUS BIOSYNTHESIS
PROTEIN F
(Vibrio
cholerae) 		4 / 7 THR A 117
TYR A 121
ASN A 123
LEU A 127
 None
 1.08A 1qzrA-3oc5A:
undetectable		 1qzrA-3oc5A:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3oc5 TOXIN COREGULATED
PILUS BIOSYNTHESIS
PROTEIN F
(Vibrio
cholerae) 		3 / 3 GLU A 144
GLU A 108
LEU A 164
 None
 0.71A 1v8bA-3oc5A:
undetectable		 1v8bA-3oc5A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z9X_B_PXLB2503_1
(ASPARTATE
AMINOTRANSFERASE)		 3oc5 TOXIN COREGULATED
PILUS BIOSYNTHESIS
PROTEIN F
(Vibrio
cholerae) 		5 / 11 PRO A 184
VAL A 151
THR A 176
VAL A 179
SER A 178
 None
 1.42A 2z9xB-3oc5A:
undetectable		 2z9xB-3oc5A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_A_SALA257_1
(TRANSCRIPTIONAL
REGULATOR)		 3oc5 TOXIN COREGULATED
PILUS BIOSYNTHESIS
PROTEIN F
(Vibrio
cholerae) 		4 / 8 SER A 310
ALA A 209
PHE A 231
THR A 273
 None
 0.97A 3bpxA-3oc5A:
undetectable
3bpxB-3oc5A:
undetectable		 3bpxA-3oc5A:
17.01
3bpxB-3oc5A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_D_MTXD2000_2
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3oc5 TOXIN COREGULATED
PILUS BIOSYNTHESIS
PROTEIN F
(Vibrio
cholerae) 		3 / 3 LEU A 297
ARG A 112
ASN A 145
 None
 0.74A 3qxvD-3oc5A:
3.4		 3qxvD-3oc5A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_2
(DIPEPTIDYL PEPTIDASE
4)		 3oc5 TOXIN COREGULATED
PILUS BIOSYNTHESIS
PROTEIN F
(Vibrio
cholerae) 		3 / 3 PHE A  79
TYR A  99
TYR A  63
 None
 1.04A 4ffwA-3oc5A:
undetectable		 4ffwA-3oc5A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_1
(TUBULIN BETA-2B
CHAIN
TUBULIN ALPHA-1B
CHAIN)		 3oc5 TOXIN COREGULATED
PILUS BIOSYNTHESIS
PROTEIN F
(Vibrio
cholerae) 		5 / 9 ASP A  97
THR A 111
PRO A 110
TYR A 148
LEU A 141
 None
 1.45A 5j2tB-3oc5A:
0.0		 5j2tB-3oc5A:
19.78