SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oc6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A 168
LEU A 155
GLY A  71
HIS A 142
PHE A 132
 None
 1.41A 1d4fC-3oc6A:
undetectable		 1d4fC-3oc6A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DYI_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ALA A 223
THR A   4
ILE A   6
ARG A   8
LEU A 244
 None
 1.09A 1dyiA-3oc6A:
undetectable		 1dyiA-3oc6A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		4 / 8 SER A 173
VAL A 172
PRO A 176
VAL A 219
 None
 0.81A 1fduB-3oc6A:
undetectable		 1fduB-3oc6A:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		3 / 4 LYS A 205
ALA A 208
MET A 146
 None
 0.76A 1hk3A-3oc6A:
undetectable		 1hk3A-3oc6A:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V2X_A_SAMA400_0
(TRNA (GM18)
METHYLTRANSFERASE)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY A  49
GLY A  45
LEU A 235
VAL A  16
ALA A  19
 None
 1.03A 1v2xA-3oc6A:
undetectable		 1v2xA-3oc6A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA502_1
(CYTOCHROME P450 2B4)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A  92
LEU A  93
ILE A  96
ILE A  61
THR A  38
 None
 1.01A 2bdmA-3oc6A:
undetectable		 2bdmA-3oc6A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		4 / 8 SER A 201
THR A  46
ALA A  18
ALA A  19
 None
 0.65A 3ax9B-3oc6A:
undetectable		 3ax9B-3oc6A:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_1
(ADENOSYLHOMOCYSTEINA
SE)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A 168
LEU A 155
GLY A  71
HIS A 142
PHE A 132
 None
 1.33A 3glqA-3oc6A:
undetectable		 3glqA-3oc6A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_1
(ADENOSYLHOMOCYSTEINA
SE)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A 168
LEU A 155
GLY A  71
HIS A 142
PHE A 132
 None
 1.36A 3glqB-3oc6A:
undetectable		 3glqB-3oc6A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A 168
LEU A 155
GLY A  71
HIS A 142
PHE A 132
 None
 1.37A 3n58A-3oc6A:
undetectable		 3n58A-3oc6A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_L_PM6L1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		4 / 8 SER A 201
THR A  46
ALA A  18
ALA A  19
 None
 0.67A 3ns1L-3oc6A:
1.3		 3ns1L-3oc6A:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQB_A_FOLA2001_0
(DIHYDROFOLATE
REDUCTASE)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 ALA A 223
LEU A 198
THR A   4
ILE A   6
LEU A 244
 None
 0.90A 3tqbA-3oc6A:
undetectable		 3tqbA-3oc6A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		4 / 8 VAL A  54
LEU A  51
LEU A  50
ILE A  39
 None
 0.90A 3u5kA-3oc6A:
undetectable		 3u5kA-3oc6A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_B_08JB2_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		4 / 7 VAL A  54
LEU A  51
LEU A  50
ILE A  39
 None
 0.92A 3u5kB-3oc6A:
undetectable		 3u5kB-3oc6A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		4 / 8 VAL A  54
LEU A  51
LEU A  50
ILE A  39
 None
 0.92A 3u5kC-3oc6A:
undetectable		 3u5kC-3oc6A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_A_SAMA801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY A  71
THR A 184
VAL A 103
ASN A  84
LEU A  93
 None
 1.15A 3v8vA-3oc6A:
undetectable		 3v8vA-3oc6A:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_A_TYLA1188_1
(BROMODOMAIN
CONTAINING 2)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		4 / 5 VAL A  54
LEU A  51
LEU A  50
ILE A  39
 None
 0.90A 4a9jA-3oc6A:
undetectable		 4a9jA-3oc6A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_A_TYLA1188_1
(BROMODOMAIN
CONTAINING 2)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		4 / 5 VAL A  54
LEU A  92
LEU A  51
ILE A  39
 None
 0.94A 4a9jA-3oc6A:
undetectable		 4a9jA-3oc6A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		4 / 5 VAL A  54
LEU A  51
LEU A  50
ILE A  39
 None
 0.85A 4a9jB-3oc6A:
undetectable		 4a9jB-3oc6A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		4 / 5 VAL A  54
LEU A  92
LEU A  51
ILE A  39
 None
 0.90A 4a9jB-3oc6A:
undetectable		 4a9jB-3oc6A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_C_TYLC1184_1
(BROMODOMAIN
CONTAINING 2)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		4 / 5 VAL A  54
LEU A  51
LEU A  50
ILE A  39
 None
 0.93A 4a9jC-3oc6A:
undetectable		 4a9jC-3oc6A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_C_TYLC1184_1
(BROMODOMAIN
CONTAINING 2)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		4 / 5 VAL A  54
LEU A  92
LEU A  51
ILE A  39
 None
 0.87A 4a9jC-3oc6A:
undetectable		 4a9jC-3oc6A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFR_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ALA A 223
THR A   4
ILE A   6
ARG A   8
LEU A 244
 None
 1.07A 4dfrA-3oc6A:
undetectable		 4dfrA-3oc6A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJ1_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ALA A 223
THR A   4
ILE A   6
ARG A   8
LEU A 244
 None
 0.97A 4ej1A-3oc6A:
undetectable		 4ej1A-3oc6A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJK_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ALA A 223
THR A   4
ILE A   6
ARG A   8
LEU A 244
 None
 1.07A 4kjkA-3oc6A:
undetectable		 4kjkA-3oc6A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_B_MTXB603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 VAL A  24
LEU A 143
LEU A  51
LYS A  52
ILE A  68
 None
 1.03A 4ky8B-3oc6A:
undetectable		 4ky8B-3oc6A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_1
(MDR769 HIV-1
PROTEASE)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 ARG A  74
ALA A 161
ASP A 160
PRO A 176
VAL A 172
 None
 1.04A 4l1aA-3oc6A:
undetectable		 4l1aA-3oc6A:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		4 / 6 VAL A  54
VAL A  24
ILE A  27
LEU A  41
 None
 0.97A 4l1wB-3oc6A:
undetectable		 4l1wB-3oc6A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 VAL A 169
ALA A 121
TYR A 124
PHE A 132
GLY A 123
 None
 1.28A 4mm4A-3oc6A:
undetectable		 4mm4A-3oc6A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_1
(TRANSPORTER)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 VAL A 169
ALA A 121
TYR A 124
PHE A 132
GLY A 123
 None
 1.30A 4mm4B-3oc6A:
undetectable		 4mm4B-3oc6A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_K_IPHK101_0
(INSULIN)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A  51
VAL A  40
ILE A  39
LEU A  93
ALA A  88
 None
 1.01A 4p65F-3oc6A:
undetectable
4p65H-3oc6A:
undetectable
4p65K-3oc6A:
undetectable
4p65L-3oc6A:
undetectable		 4p65F-3oc6A:
12.03
4p65H-3oc6A:
12.03
4p65K-3oc6A:
7.64
4p65L-3oc6A:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A 155
ASN A 153
GLY A  71
HIS A 142
PHE A 132
 None
 1.22A 4pgfA-3oc6A:
undetectable		 4pgfA-3oc6A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A 168
LEU A 155
GLY A  71
HIS A 142
PHE A 132
 None
 1.32A 4pgfA-3oc6A:
undetectable		 4pgfA-3oc6A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLE_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ALA A 223
THR A   4
ILE A   6
ARG A   8
LEU A 244
 None
 1.04A 4qleA-3oc6A:
undetectable		 4qleA-3oc6A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5F_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ALA A 223
THR A   4
ILE A   6
ARG A   8
LEU A 244
 None
 1.07A 4x5fA-3oc6A:
undetectable		 4x5fA-3oc6A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5F_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ALA A 223
THR A   4
ILE A   6
ARG A   8
LEU A 244
 None
 1.05A 4x5fB-3oc6A:
undetectable		 4x5fB-3oc6A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5G_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ALA A 223
THR A   4
ILE A   6
ARG A   8
LEU A 244
 None
 1.03A 4x5gA-3oc6A:
undetectable		 4x5gA-3oc6A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5G_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ALA A 223
THR A   4
ILE A   6
ARG A   8
LEU A 244
 None
 1.04A 4x5gB-3oc6A:
undetectable		 4x5gB-3oc6A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5H_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ALA A 223
THR A   4
ILE A   6
ARG A   8
LEU A 244
 None
 1.01A 4x5hA-3oc6A:
undetectable		 4x5hA-3oc6A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		3 / 3 THR A 159
ASP A 160
ALA A 161
 None
 0.09A 5g5gB-3oc6A:
undetectable		 5g5gB-3oc6A:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A 128
SER A 129
PHE A 132
ASP A 133
 None
 0.61A 5om3A-3oc6A:
undetectable
5om3B-3oc6A:
undetectable		 5om3A-3oc6A:
13.79
5om3B-3oc6A:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A 168
LEU A 155
GLY A  71
HIS A 142
PHE A 132
 None
 1.33A 6aphA-3oc6A:
undetectable		 6aphA-3oc6A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CB4_A_BEZA501_0
(CANAVALIN)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		4 / 8 LEU A  51
VAL A  24
LEU A  23
ILE A  27
 None
 0.91A 6cb4A-3oc6A:
undetectable		 6cb4A-3oc6A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_1
(-)		 3oc6 6-PHOSPHOGLUCONOLACT
ONASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A 168
LEU A 155
GLY A  71
HIS A 142
PHE A 132
 None
 1.37A 6gbnB-3oc6A:
undetectable		 6gbnB-3oc6A:
20.19