SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oc7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_C_ESTC353_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3oc7 ENOYL-COA HYDRATASE
(Mycobacterium
avium) 		5 / 12 VAL A 123
GLY A 124
LEU A 155
GLY A 119
TYR A 168
 None
 1.16A 1fduC-3oc7A:
undetectable		 1fduC-3oc7A:
25.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IOL_A_ESTA400_1
(ESTROGENIC 17-BETA
HYDROXYSTEROID
DEHYDROGENASE)		 3oc7 ENOYL-COA HYDRATASE
(Mycobacterium
avium) 		5 / 11 VAL A 123
GLY A 124
LEU A 155
GLY A 119
TYR A 168
 None
 1.13A 1iolA-3oc7A:
undetectable		 1iolA-3oc7A:
25.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_1
(RETINOIC ACID
RECEPTOR, BETA)		 3oc7 ENOYL-COA HYDRATASE
(Mycobacterium
avium) 		5 / 12 LEU A 159
LEU A 184
ILE A 182
SER A 135
LEU A 155
 None
 0.99A 1xdkF-3oc7A:
undetectable		 1xdkF-3oc7A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_0
(ESTROGEN RECEPTOR)		 3oc7 ENOYL-COA HYDRATASE
(Mycobacterium
avium) 		5 / 12 LEU A 156
LEU A 223
LEU A 233
ILE A 151
GLY A 121
 None
 1.03A 2ouzA-3oc7A:
undetectable		 2ouzA-3oc7A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3oc7 ENOYL-COA HYDRATASE
(Mycobacterium
avium) 		4 / 6 PHE A 174
LEU A 155
PRO A 148
ALA A 138
 None
 0.98A 2vcvK-3oc7A:
undetectable		 2vcvK-3oc7A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		 3oc7 ENOYL-COA HYDRATASE
(Mycobacterium
avium) 		3 / 3 PHE A 120
TYR A 167
LEU A 153
 None
 0.63A 3keeB-3oc7A:
undetectable		 3keeB-3oc7A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZV_B_ECNB411_1
(FLAVOHEMOGLOBIN)		 3oc7 ENOYL-COA HYDRATASE
(Mycobacterium
avium) 		5 / 9 ILE A 100
ALA A  58
LEU A  57
LEU A  96
ALA A  99
 None
 1.07A 3ozvB-3oc7A:
undetectable		 3ozvB-3oc7A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3oc7 ENOYL-COA HYDRATASE
(Mycobacterium
avium) 		3 / 3 PHE A 120
TYR A 167
LEU A 153
 None
 0.61A 3sueB-3oc7A:
undetectable		 3sueB-3oc7A:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_E_CHDE104_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3oc7 ENOYL-COA HYDRATASE
(Mycobacterium
avium) 		5 / 11 ALA A  68
LEU A  31
GLU A  92
LEU A  96
LEU A 122
 None
 0.92A 4wg0C-3oc7A:
undetectable
4wg0D-3oc7A:
undetectable
4wg0E-3oc7A:
undetectable		 4wg0C-3oc7A:
4.74
4wg0D-3oc7A:
4.74
4wg0E-3oc7A:
4.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_G_CHDG103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3oc7 ENOYL-COA HYDRATASE
(Mycobacterium
avium) 		5 / 11 ALA A  68
LEU A  31
GLU A  92
LEU A  96
LEU A 122
 None
 0.91A 4wg0E-3oc7A:
undetectable
4wg0F-3oc7A:
undetectable
4wg0G-3oc7A:
undetectable		 4wg0E-3oc7A:
4.74
4wg0F-3oc7A:
4.74
4wg0G-3oc7A:
4.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE0_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3oc7 ENOYL-COA HYDRATASE
(Mycobacterium
avium) 		5 / 9 PHE A  64
ILE A 111
GLY A 119
LEU A 155
LEU A 159
 None
 1.28A 4ze0A-3oc7A:
2.3		 4ze0A-3oc7A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DB5_A_CYSA503_0
(CYSTEINE DESULFURASE)		 3oc7 ENOYL-COA HYDRATASE
(Mycobacterium
avium) 		4 / 8 ALA A  66
HIS A  59
ARG A  28
HIS A 114
 None
 1.25A 5db5A-3oc7A:
undetectable
5db5B-3oc7A:
undetectable		 5db5A-3oc7A:
22.44
5db5B-3oc7A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DB5_A_CYSA503_0
(CYSTEINE DESULFURASE)		 3oc7 ENOYL-COA HYDRATASE
(Mycobacterium
avium) 		4 / 8 ALA A  66
HIS A  59
ASN A  29
ARG A  28
 None
 1.08A 5db5A-3oc7A:
undetectable
5db5B-3oc7A:
undetectable		 5db5A-3oc7A:
22.44
5db5B-3oc7A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)		 3oc7 ENOYL-COA HYDRATASE
(Mycobacterium
avium) 		4 / 8 ILE A 111
GLU A 141
THR A 140
ALA A 138
 None
 0.73A 5og9A-3oc7A:
undetectable		 5og9A-3oc7A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB306_0
(WELO5)		 3oc7 ENOYL-COA HYDRATASE
(Mycobacterium
avium) 		3 / 3 GLU A 172
ARG A 166
TYR A 167
 None
 0.59A 5trqB-3oc7A:
undetectable		 5trqB-3oc7A:
23.10