SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oc9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 3oc9 UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Entamoeba
histolytica) 		3 / 3 THR A  12
THR A  10
PRO A  14
 None
 0.83A 1a7yB-3oc9A:
undetectable		 1a7yB-3oc9A:
2.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 3oc9 UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 12 LEU A 267
LEU A 156
MET A 169
ILE A 165
GLY A 164
 None
 1.27A 1g50B-3oc9A:
undetectable		 1g50B-3oc9A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 3oc9 UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 11 LEU A 267
LEU A 156
MET A 169
ILE A 165
GLY A 164
 None
 1.27A 1g50C-3oc9A:
undetectable		 1g50C-3oc9A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 3oc9 UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Entamoeba
histolytica) 		3 / 3 THR A  12
THR A  10
PRO A  14
 None
 0.78A 1qfiB-3oc9A:
undetectable		 1qfiB-3oc9A:
2.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3oc9 UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Entamoeba
histolytica) 		3 / 3 HIS A 153
ASP A 183
ASN A 334
 None
 0.64A 1wg8B-3oc9A:
undetectable		 1wg8B-3oc9A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 3oc9 UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 11 VAL A 182
GLY A  39
ILE A 104
LEU A  94
THR A  96
 None
 1.05A 3bexC-3oc9A:
undetectable
3bexD-3oc9A:
undetectable		 3bexC-3oc9A:
21.92
3bexD-3oc9A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 3oc9 UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 10 LEU A  94
THR A  96
VAL A 182
GLY A  39
ILE A 104
 None
 1.05A 3bexC-3oc9A:
undetectable
3bexD-3oc9A:
undetectable		 3bexC-3oc9A:
21.92
3bexD-3oc9A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 3oc9 UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 10 VAL A 182
GLY A  39
ILE A 104
LEU A  94
THR A  96
 None
 1.05A 3bexE-3oc9A:
undetectable
3bexF-3oc9A:
undetectable		 3bexE-3oc9A:
21.92
3bexF-3oc9A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 3oc9 UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 11 LEU A  94
THR A  96
VAL A 182
GLY A  39
ILE A 104
 None
 1.05A 3bexE-3oc9A:
undetectable
3bexF-3oc9A:
undetectable		 3bexE-3oc9A:
21.92
3bexF-3oc9A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 3oc9 UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 11 VAL A 182
GLY A  39
ILE A 104
LEU A  94
THR A  96
 None
 1.06A 3bf1A-3oc9A:
undetectable
3bf1B-3oc9A:
undetectable		 3bf1A-3oc9A:
21.92
3bf1B-3oc9A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 3oc9 UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 12 LEU A  94
THR A  96
VAL A 182
GLY A  39
ILE A 104
 None
 1.06A 3bf1A-3oc9A:
undetectable
3bf1B-3oc9A:
undetectable		 3bf1A-3oc9A:
21.92
3bf1B-3oc9A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 3oc9 UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 11 VAL A 182
GLY A  39
ILE A 104
LEU A  94
THR A  96
 None
 1.05A 3bf1C-3oc9A:
undetectable
3bf1D-3oc9A:
undetectable		 3bf1C-3oc9A:
21.92
3bf1D-3oc9A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 3oc9 UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 11 LEU A  94
THR A  96
VAL A 182
GLY A  39
ILE A 104
 None
 1.09A 3bf1C-3oc9A:
undetectable
3bf1D-3oc9A:
undetectable		 3bf1C-3oc9A:
21.92
3bf1D-3oc9A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 3oc9 UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 11 VAL A 182
GLY A  39
ILE A 104
LEU A  94
THR A  96
 None
 1.06A 3bf1E-3oc9A:
undetectable
3bf1F-3oc9A:
undetectable		 3bf1E-3oc9A:
21.92
3bf1F-3oc9A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 3oc9 UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 11 LEU A  94
THR A  96
VAL A 182
GLY A  39
ILE A 104
 None
 1.05A 3bf1E-3oc9A:
undetectable
3bf1F-3oc9A:
undetectable		 3bf1E-3oc9A:
21.92
3bf1F-3oc9A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3oc9 UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Entamoeba
histolytica) 		4 / 5 VAL A 182
PHE A 308
PHE A 307
PHE A 309
 None
 1.07A 3owxB-3oc9A:
undetectable		 3owxB-3oc9A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SOA_A_DB8A445_1
(CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA WITH A
BETA 7 LINKER)		 3oc9 UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Entamoeba
histolytica) 		4 / 6 LEU A 332
VAL A 346
PHE A  58
PHE A 377
 None
 1.06A 3soaA-3oc9A:
undetectable		 3soaA-3oc9A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HXY_B_ACAB502_1
(PLM1)		 3oc9 UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Entamoeba
histolytica) 		4 / 7 VAL A  15
SER A 319
TYR A 197
ASP A 191
 None
 1.10A 4hxyB-3oc9A:
undetectable		 4hxyB-3oc9A:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7U_D_YTZD802_1
(SEPIAPTERIN
REDUCTASE)		 3oc9 UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Entamoeba
histolytica) 		4 / 8 LEU A  56
TRP A 350
TYR A 351
GLN A 401
 None
 1.21A 4j7uD-3oc9A:
2.0		 4j7uD-3oc9A:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_A_PAUA301_0
(TYPE III
PANTOTHENATE KINASE)		 3oc9 UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 12 VAL A 182
GLY A  39
ILE A 104
LEU A  94
THR A  96
 None
 1.04A 4o5fA-3oc9A:
undetectable
4o5fB-3oc9A:
undetectable		 4o5fA-3oc9A:
18.94
4o5fB-3oc9A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 3oc9 UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 12 LEU A  94
THR A  96
VAL A 182
GLY A  39
ILE A 104
 None
 1.05A 4o5fA-3oc9A:
undetectable
4o5fB-3oc9A:
undetectable		 4o5fA-3oc9A:
18.94
4o5fB-3oc9A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_A_PAUA302_0
(TYPE III
PANTOTHENATE KINASE)		 3oc9 UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 12 VAL A 182
GLY A  39
ILE A 104
LEU A  94
THR A  96
 None
 1.07A 5b8hA-3oc9A:
undetectable
5b8hB-3oc9A:
undetectable		 5b8hA-3oc9A:
18.32
5b8hB-3oc9A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 3oc9 UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 12 LEU A  94
THR A  96
VAL A 182
GLY A  39
ILE A 104
 None
 1.06A 5b8hA-3oc9A:
undetectable
5b8hB-3oc9A:
undetectable		 5b8hA-3oc9A:
18.32
5b8hB-3oc9A:
18.32