SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oce'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 3oce FUMARATE LYASE:DELTA
CRYSTALLIN
(Brucella
abortus) 		5 / 12 PHE A 203
LEU A 305
GLY A 184
GLY A 197
LEU A 196
 None
None
None
EDO  A 475 ( 4.3A)
None
 1.08A 1fe2A-3oceA:
undetectable		 1fe2A-3oceA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 3oce FUMARATE LYASE:DELTA
CRYSTALLIN
(Brucella
abortus) 		5 / 12 PHE A 203
LEU A 305
GLY A 184
GLY A 197
LEU A 196
 None
None
None
EDO  A 475 ( 4.3A)
None
 1.04A 1igxA-3oceA:
undetectable		 1igxA-3oceA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3oce FUMARATE LYASE:DELTA
CRYSTALLIN
(Brucella
abortus) 		4 / 8 LEU A 163
VAL A 159
GLY A 376
VAL A 339
 None
 0.91A 2a1oA-3oceA:
undetectable		 2a1oA-3oceA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3oce FUMARATE LYASE:DELTA
CRYSTALLIN
(Brucella
abortus) 		4 / 8 ASN A 105
SER A 102
TYR A 144
PHE A  31
 None
 1.24A 2wekA-3oceA:
undetectable		 2wekA-3oceA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3oce FUMARATE LYASE:DELTA
CRYSTALLIN
(Brucella
abortus) 		4 / 8 ASN A 105
SER A 102
TYR A 144
PHE A  31
 None
 1.25A 2wekB-3oceA:
undetectable		 2wekB-3oceA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 3oce FUMARATE LYASE:DELTA
CRYSTALLIN
(Brucella
abortus) 		5 / 12 ILE A 390
LEU A 294
ILE A 308
ARG A 185
ILE A 290
 None
 1.06A 2ygnA-3oceA:
undetectable		 2ygnA-3oceA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_B_VDYB6178_1
(VITAMIN D
HYDROXYLASE)		 3oce FUMARATE LYASE:DELTA
CRYSTALLIN
(Brucella
abortus) 		5 / 12 PRO A 329
LEU A 310
ASN A 292
VAL A 180
LEU A 196
 None
 1.20A 3a51B-3oceA:
undetectable		 3a51B-3oceA:
25.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3oce FUMARATE LYASE:DELTA
CRYSTALLIN
(Brucella
abortus) 		4 / 5 PHE A 273
ILE A 368
PHE A 276
PHE A 221
 None
 1.06A 3owxB-3oceA:
undetectable		 3owxB-3oceA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_A_SAMA300_0
(PUTATIVE
METHYLTRANSFERASE)		 3oce FUMARATE LYASE:DELTA
CRYSTALLIN
(Brucella
abortus) 		5 / 12 ARG A  12
GLN A  23
GLY A  21
GLU A  29
ALA A  27
 None
 1.23A 3t7sA-3oceA:
undetectable		 3t7sA-3oceA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA1_1
(CYTOCHROME P450 2D6)		 3oce FUMARATE LYASE:DELTA
CRYSTALLIN
(Brucella
abortus) 		5 / 12 PHE A 276
LEU A 152
GLY A 376
LEU A 375
GLN A 158
 None
 1.28A 3tbgA-3oceA:
undetectable		 3tbgA-3oceA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC1_1
(CYTOCHROME P450 2D6)		 3oce FUMARATE LYASE:DELTA
CRYSTALLIN
(Brucella
abortus) 		5 / 12 PHE A 276
LEU A 152
GLY A 376
LEU A 375
GLN A 158
 None
 1.30A 3tbgC-3oceA:
1.5		 3tbgC-3oceA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 3oce FUMARATE LYASE:DELTA
CRYSTALLIN
(Brucella
abortus) 		3 / 3 PRO A 121
LEU A 115
HIS A 129
 None
 0.57A 4pevA-3oceA:
undetectable		 4pevA-3oceA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 3oce FUMARATE LYASE:DELTA
CRYSTALLIN
(Brucella
abortus) 		5 / 11 GLY A 123
GLU A   5
ILE A  22
ASP A   7
PRO A 130
 None
 1.32A 5hjiA-3oceA:
undetectable		 5hjiA-3oceA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_A_08JA602_1
(CYTOCHROME P450 3A4)		 3oce FUMARATE LYASE:DELTA
CRYSTALLIN
(Brucella
abortus) 		4 / 7 ALA A 178
THR A 195
ILE A 181
LEU A 455
 EDO  A 475 ( 4.0A)
None
None
None
 0.98A 5te8A-3oceA:
0.2		 5te8A-3oceA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_B_SAMB501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 3oce FUMARATE LYASE:DELTA
CRYSTALLIN
(Brucella
abortus) 		5 / 12 ALA A 114
GLY A 119
ILE A 110
GLY A  21
ASP A 124
 None
 1.17A 5wwsB-3oceA:
undetectable		 5wwsB-3oceA:
22.79