SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ocm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_4
(HIV-1 PROTEASE)		 3ocm PUTATIVE MEMBRANE
PROTEIN
(Bordetella
parapertussis) 		4 / 4 ARG A 383
ASP A 343
GLY A 440
THR A 443
 None
None
None
ADP  A 470 (-3.0A)
 1.31A 3k4vB-3ocmA:
undetectable		 3k4vB-3ocmA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3ocm PUTATIVE MEMBRANE
PROTEIN
(Bordetella
parapertussis) 		5 / 12 THR A 443
ASP A 446
THR A 339
VAL A 344
PRO A 369
 ADP  A 470 (-3.0A)
ADP  A 470 (-2.8A)
ADP  A 470 (-3.6A)
ADP  A 470 ( 4.0A)
None
 0.57A 3kpbA-3ocmA:
10.2		 3kpbA-3ocmA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3ocm PUTATIVE MEMBRANE
PROTEIN
(Bordetella
parapertussis) 		5 / 12 THR A 443
ASP A 446
THR A 339
VAL A 344
PRO A 369
 ADP  A 470 (-3.0A)
ADP  A 470 (-2.8A)
ADP  A 470 (-3.6A)
ADP  A 470 ( 4.0A)
None
 0.58A 3kpbC-3ocmA:
10.1		 3kpbC-3ocmA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPC_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3ocm PUTATIVE MEMBRANE
PROTEIN
(Bordetella
parapertussis) 		5 / 11 THR A 443
ASP A 446
THR A 339
VAL A 344
PRO A 369
 ADP  A 470 (-3.0A)
ADP  A 470 (-2.8A)
ADP  A 470 (-3.6A)
ADP  A 470 ( 4.0A)
None
 0.66A 3kpcA-3ocmA:
10.6		 3kpcA-3ocmA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3ocm PUTATIVE MEMBRANE
PROTEIN
(Bordetella
parapertussis) 		5 / 12 THR A 443
ASP A 446
THR A 339
VAL A 344
PRO A 369
 ADP  A 470 (-3.0A)
ADP  A 470 (-2.8A)
ADP  A 470 (-3.6A)
ADP  A 470 ( 4.0A)
None
 0.65A 3kpdB-3ocmA:
10.1		 3kpdB-3ocmA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 3ocm PUTATIVE MEMBRANE
PROTEIN
(Bordetella
parapertussis) 		5 / 12 THR A 443
ASP A 446
THR A 339
VAL A 344
PRO A 369
 ADP  A 470 (-3.0A)
ADP  A 470 (-2.8A)
ADP  A 470 (-3.6A)
ADP  A 470 ( 4.0A)
None
 0.63A 3kpdC-3ocmA:
10.1		 3kpdC-3ocmA:
22.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OI8_A_ADNA2_1
(UNCHARACTERIZED
PROTEIN)		 3ocm PUTATIVE MEMBRANE
PROTEIN
(Bordetella
parapertussis) 		4 / 6 HIS A 365
PRO A 369
LEU A 441
ASP A 446
 ADP  A 470 ( 3.3A)
None
ADP  A 470 (-4.8A)
ADP  A 470 (-2.8A)
 0.75A 3oi8A-3ocmA:
6.1		 3oi8A-3ocmA:
31.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OI8_B_ADNB1_1
(UNCHARACTERIZED
PROTEIN)		 3ocm PUTATIVE MEMBRANE
PROTEIN
(Bordetella
parapertussis) 		5 / 9 HIS A 365
PRO A 369
LEU A 441
THR A 443
ASP A 446
 ADP  A 470 ( 3.3A)
None
ADP  A 470 (-4.8A)
ADP  A 470 (-3.0A)
ADP  A 470 (-2.8A)
 0.88A 3oi8A-3ocmA:
6.1
3oi8B-3ocmA:
6.0		 3oi8A-3ocmA:
31.49
3oi8B-3ocmA:
31.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3ocm PUTATIVE MEMBRANE
PROTEIN
(Bordetella
parapertussis) 		4 / 7 PRO A 369
THR A 443
ILE A 445
ASP A 446
 None
ADP  A 470 (-3.0A)
ADP  A 470 (-4.1A)
ADP  A 470 (-2.8A)
 0.54A 4pcuA-3ocmA:
10.1		 4pcuA-3ocmA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 3ocm PUTATIVE MEMBRANE
PROTEIN
(Bordetella
parapertussis) 		3 / 3 THR A 443
ASP A 457
GLU A 454
 ADP  A 470 (-3.0A)
ADP  A 470 (-3.5A)
MG  A   7 ( 4.1A)
 0.86A 5fa8A-3ocmA:
undetectable		 5fa8A-3ocmA:
26.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_E_LLLE301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3ocm PUTATIVE MEMBRANE
PROTEIN
(Bordetella
parapertussis) 		4 / 7 ASP A 433
ASP A 376
CYH A 371
GLU A 377
 None
 1.35A 6mn5E-3ocmA:
undetectable		 6mn5E-3ocmA:
19.19