SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ocr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3ocr CLASS II
ALDOLASE/ADDUCIN
DOMAIN PROTEIN
(Pseudomonas
savastanoi) 		5 / 12 ILE A 102
VAL A  87
ASP A  88
ALA A 116
TYR A 104
 None
 1.14A 1kiaB-3ocrA:
undetectable		 1kiaB-3ocrA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3ocr CLASS II
ALDOLASE/ADDUCIN
DOMAIN PROTEIN
(Pseudomonas
savastanoi) 		5 / 12 ILE A 102
VAL A  87
ASP A  88
ALA A 116
TYR A 104
 None
 1.13A 1kiaC-3ocrA:
undetectable		 1kiaC-3ocrA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3ocr CLASS II
ALDOLASE/ADDUCIN
DOMAIN PROTEIN
(Pseudomonas
savastanoi) 		5 / 12 ILE A 102
VAL A  87
ASP A  88
ALA A 116
TYR A 104
 None
 1.17A 1nbhC-3ocrA:
undetectable		 1nbhC-3ocrA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3ocr CLASS II
ALDOLASE/ADDUCIN
DOMAIN PROTEIN
(Pseudomonas
savastanoi) 		5 / 12 VAL A 155
PHE A 151
SER A 148
SER A 145
GLY A 131
 None
 1.16A 2x2iA-3ocrA:
undetectable		 2x2iA-3ocrA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3ocr CLASS II
ALDOLASE/ADDUCIN
DOMAIN PROTEIN
(Pseudomonas
savastanoi) 		5 / 10 VAL A 155
PHE A 151
SER A 148
SER A 145
GLY A 131
 None
 1.16A 2x2iB-3ocrA:
undetectable		 2x2iB-3ocrA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3ocr CLASS II
ALDOLASE/ADDUCIN
DOMAIN PROTEIN
(Pseudomonas
savastanoi) 		5 / 12 VAL A 155
PHE A 151
SER A 148
SER A 145
GLY A 131
 None
 1.18A 2x2iC-3ocrA:
undetectable		 2x2iC-3ocrA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_D_QPSD1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3ocr CLASS II
ALDOLASE/ADDUCIN
DOMAIN PROTEIN
(Pseudomonas
savastanoi) 		5 / 10 VAL A 155
PHE A 151
SER A 148
SER A 145
GLY A 131
 None
 1.19A 2x2iD-3ocrA:
undetectable		 2x2iD-3ocrA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 3ocr CLASS II
ALDOLASE/ADDUCIN
DOMAIN PROTEIN
(Pseudomonas
savastanoi) 		4 / 6 TYR A  40
ALA A  39
LEU A  36
ALA A 122
 None
 0.86A 3b6hB-3ocrA:
undetectable		 3b6hB-3ocrA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)		 3ocr CLASS II
ALDOLASE/ADDUCIN
DOMAIN PROTEIN
(Pseudomonas
savastanoi) 		4 / 6 VAL A 134
LEU A 190
GLU A 208
CYH A 211
 None
 1.11A 3b6rB-3ocrA:
2.1		 3b6rB-3ocrA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 3ocr CLASS II
ALDOLASE/ADDUCIN
DOMAIN PROTEIN
(Pseudomonas
savastanoi) 		4 / 8 HIS A  55
ILE A  52
PHE A  72
TYR A  53
 None
 1.39A 3ccfB-3ocrA:
undetectable		 3ccfB-3ocrA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3ocr CLASS II
ALDOLASE/ADDUCIN
DOMAIN PROTEIN
(Pseudomonas
savastanoi) 		4 / 6 SER A  57
ALA A  58
HIS A 110
LEU A 124
 None
 1.20A 5dzkB-3ocrA:
undetectable
5dzkP-3ocrA:
undetectable		 5dzkB-3ocrA:
22.76
5dzkP-3ocrA:
1.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3ocr CLASS II
ALDOLASE/ADDUCIN
DOMAIN PROTEIN
(Pseudomonas
savastanoi) 		4 / 5 SER A  57
ALA A  58
HIS A 110
LEU A 124
 None
 1.16A 5dzkc-3ocrA:
undetectable
5dzkq-3ocrA:
undetectable		 5dzkc-3ocrA:
22.76
5dzkq-3ocrA:
1.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3ocr CLASS II
ALDOLASE/ADDUCIN
DOMAIN PROTEIN
(Pseudomonas
savastanoi) 		4 / 5 SER A  57
ALA A  58
HIS A 110
LEU A 124
 None
 1.36A 5dzkf-3ocrA:
undetectable
5dzkt-3ocrA:
undetectable		 5dzkf-3ocrA:
22.76
5dzkt-3ocrA:
1.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3ocr CLASS II
ALDOLASE/ADDUCIN
DOMAIN PROTEIN
(Pseudomonas
savastanoi) 		4 / 8 SER A  57
ALA A  58
HIS A 110
LEU A 124
 None
 1.14A 5dzkF-3ocrA:
undetectable
5dzkT-3ocrA:
undetectable		 5dzkF-3ocrA:
22.76
5dzkT-3ocrA:
1.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_U_BEZU801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3ocr CLASS II
ALDOLASE/ADDUCIN
DOMAIN PROTEIN
(Pseudomonas
savastanoi) 		4 / 6 SER A  57
ALA A  58
HIS A 110
LEU A 124
 None
 1.18A 5dzkg-3ocrA:
undetectable
5dzku-3ocrA:
undetectable		 5dzkg-3ocrA:
22.76
5dzku-3ocrA:
1.04