SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3odg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_B_TESB904_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		4 / 7 TYR A 172
ILE A  39
HIS A 144
LEU A 230
 None
 0.99A 1j96B-3odgA:
undetectable		 1j96B-3odgA:
21.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PWY_E_AC2E290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		8 / 10 GLY A 127
PHE A 204
GLU A 205
VAL A 221
GLY A 222
MET A 223
THR A 246
ASN A 247
 XAN  A 288 (-3.5A)
None
XAN  A 288 (-2.8A)
XAN  A 288 (-4.5A)
XAN  A 288 (-3.4A)
XAN  A 288 (-4.3A)
XAN  A 288 (-3.8A)
XAN  A 288 (-3.0A)
 0.63A 1pwyE-3odgA:
36.4		 1pwyE-3odgA:
40.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PWY_E_AC2E290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		7 / 10 PHE A 204
GLU A 205
VAL A 221
GLY A 222
MET A 223
THR A 246
HIS A 259
 None
XAN  A 288 (-2.8A)
XAN  A 288 (-4.5A)
XAN  A 288 (-3.4A)
XAN  A 288 (-4.3A)
XAN  A 288 (-3.8A)
None
 0.86A 1pwyE-3odgA:
36.4		 1pwyE-3odgA:
40.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V3Q_E_2DIE290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		9 / 10 GLY A 127
PHE A 204
GLU A 205
VAL A 221
GLY A 222
MET A 223
THR A 246
ASN A 247
HIS A 259
 XAN  A 288 (-3.5A)
None
XAN  A 288 (-2.8A)
XAN  A 288 (-4.5A)
XAN  A 288 (-3.4A)
XAN  A 288 (-4.3A)
XAN  A 288 (-3.8A)
XAN  A 288 (-3.0A)
None
 0.68A 1v3qE-3odgA:
36.8		 1v3qE-3odgA:
40.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_A_RBFA300_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		5 / 11 GLY A 222
SER A 198
GLU A 205
ILE A 210
ALA A 249
 XAN  A 288 (-3.4A)
None
XAN  A 288 (-2.8A)
None
XAN  A 288 ( 4.8A)
 1.47A 2a58A-3odgA:
3.6
2a58E-3odgA:
3.7		 2a58A-3odgA:
21.92
2a58E-3odgA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_D_RBFD303_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		5 / 11 ILE A 210
ALA A 249
GLY A 222
SER A 198
GLU A 205
 None
XAN  A 288 ( 4.8A)
XAN  A 288 (-3.4A)
None
XAN  A 288 (-2.8A)
 1.46A 2a58C-3odgA:
3.9
2a58D-3odgA:
3.8		 2a58C-3odgA:
21.92
2a58D-3odgA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		5 / 12 ASP A  49
ALA A  37
CYH A  89
VAL A  78
TYR A  59
 None
 1.44A 2g70B-3odgA:
undetectable		 2g70B-3odgA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_1
(UNCHARACTERIZED
PROTEIN MJ1557)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		3 / 3 MET A 148
GLU A 205
ASN A 247
 None
XAN  A 288 (-2.8A)
XAN  A 288 (-3.0A)
 1.06A 3a27A-3odgA:
undetectable		 3a27A-3odgA:
21.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		5 / 6 GLY A 127
GLU A 205
GLY A 222
MET A 223
ASN A 247
 XAN  A 288 (-3.5A)
XAN  A 288 (-2.8A)
XAN  A 288 (-3.4A)
XAN  A 288 (-4.3A)
XAN  A 288 (-3.0A)
 0.59A 3e9rA-3odgA:
37.1		 3e9rA-3odgA:
41.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E9R_C_ACTC700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		5 / 6 GLY A 127
GLU A 205
GLY A 222
MET A 223
ASN A 247
 XAN  A 288 (-3.5A)
XAN  A 288 (-2.8A)
XAN  A 288 (-3.4A)
XAN  A 288 (-4.3A)
XAN  A 288 (-3.0A)
 0.59A 3e9rC-3odgA:
37.2		 3e9rC-3odgA:
41.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F8W_A_ADNA300_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		9 / 12 SER A  42
ALA A 125
GLY A 127
GLU A 205
VAL A 221
GLY A 222
MET A 223
ASN A 247
HIS A 259
 CL  A 289 (-3.9A)
CL  A 289 ( 3.9A)
XAN  A 288 (-3.5A)
XAN  A 288 (-2.8A)
XAN  A 288 (-4.5A)
XAN  A 288 (-3.4A)
XAN  A 288 (-4.3A)
XAN  A 288 (-3.0A)
None
 0.65A 3f8wA-3odgA:
37.3		 3f8wA-3odgA:
41.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F8W_A_ADNA300_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		9 / 12 TYR A  97
ALA A 125
GLY A 127
GLU A 205
VAL A 221
GLY A 222
MET A 223
ASN A 247
HIS A 259
 None
CL  A 289 ( 3.9A)
XAN  A 288 (-3.5A)
XAN  A 288 (-2.8A)
XAN  A 288 (-4.5A)
XAN  A 288 (-3.4A)
XAN  A 288 (-4.3A)
XAN  A 288 (-3.0A)
None
 0.48A 3f8wA-3odgA:
37.3		 3f8wA-3odgA:
41.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F8W_B_ADNB301_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		9 / 12 HIS A  95
TYR A  97
GLY A 127
GLU A 205
VAL A 221
GLY A 222
MET A 223
ASN A 247
HIS A 259
 None
None
XAN  A 288 (-3.5A)
XAN  A 288 (-2.8A)
XAN  A 288 (-4.5A)
XAN  A 288 (-3.4A)
XAN  A 288 (-4.3A)
XAN  A 288 (-3.0A)
None
 0.51A 3f8wB-3odgA:
37.0		 3f8wB-3odgA:
41.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F8W_B_ADNB301_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		8 / 12 SER A  42
GLY A 127
GLU A 205
VAL A 221
GLY A 222
MET A 223
ASN A 247
HIS A 259
 CL  A 289 (-3.9A)
XAN  A 288 (-3.5A)
XAN  A 288 (-2.8A)
XAN  A 288 (-4.5A)
XAN  A 288 (-3.4A)
XAN  A 288 (-4.3A)
XAN  A 288 (-3.0A)
None
 0.62A 3f8wB-3odgA:
37.0		 3f8wB-3odgA:
41.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F8W_C_ADNC302_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		9 / 12 HIS A  95
TYR A  97
ALA A 125
GLY A 127
GLU A 205
VAL A 221
GLY A 222
MET A 223
ASN A 247
 None
None
CL  A 289 ( 3.9A)
XAN  A 288 (-3.5A)
XAN  A 288 (-2.8A)
XAN  A 288 (-4.5A)
XAN  A 288 (-3.4A)
XAN  A 288 (-4.3A)
XAN  A 288 (-3.0A)
 0.44A 3f8wC-3odgA:
37.3		 3f8wC-3odgA:
41.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F8W_C_ADNC302_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		8 / 12 SER A  42
ALA A 125
GLY A 127
GLU A 205
VAL A 221
GLY A 222
MET A 223
ASN A 247
 CL  A 289 (-3.9A)
CL  A 289 ( 3.9A)
XAN  A 288 (-3.5A)
XAN  A 288 (-2.8A)
XAN  A 288 (-4.5A)
XAN  A 288 (-3.4A)
XAN  A 288 (-4.3A)
XAN  A 288 (-3.0A)
 0.60A 3f8wC-3odgA:
37.3		 3f8wC-3odgA:
41.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_2
(GLUCOCORTICOID
RECEPTOR 2)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		3 / 3 MET A 223
MET A 212
PHE A 204
 XAN  A 288 (-4.3A)
None
None
 1.22A 3gn8A-3odgA:
undetectable		 3gn8A-3odgA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		5 / 10 PRO A 108
SER A 231
ILE A 104
PRO A  66
GLY A  94
 None
 1.27A 3ijxB-3odgA:
undetectable
3ijxD-3odgA:
undetectable		 3ijxB-3odgA:
23.12
3ijxD-3odgA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		5 / 10 PRO A 108
SER A 231
ILE A 104
PRO A  66
GLY A  94
 None
 1.28A 3iluB-3odgA:
undetectable
3iluE-3odgA:
undetectable		 3iluB-3odgA:
23.12
3iluE-3odgA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		5 / 11 ILE A 104
PRO A  66
GLY A  94
PRO A 108
SER A 231
 None
 1.27A 3iluB-3odgA:
undetectable
3iluE-3odgA:
undetectable		 3iluB-3odgA:
23.12
3iluE-3odgA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		4 / 8 ILE A 104
PRO A  66
GLY A  94
PRO A 108
 None
 0.95A 3lslA-3odgA:
undetectable
3lslD-3odgA:
undetectable		 3lslA-3odgA:
22.50
3lslD-3odgA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		4 / 8 PRO A 108
ILE A 104
PRO A  66
GLY A  94
 None
 0.94A 3lslA-3odgA:
undetectable
3lslD-3odgA:
undetectable		 3lslA-3odgA:
22.50
3lslD-3odgA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		4 / 7 PHE A 121
PHE A  38
PHE A 273
LEU A 281
 None
 1.07A 4ejgA-3odgA:
undetectable		 4ejgA-3odgA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_A_BRLA501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		4 / 5 LEU A 281
ILE A  51
LEU A  40
LEU A 237
 None
 0.88A 4o8fA-3odgA:
undetectable		 4o8fA-3odgA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_C_Y70C151_1
(CEREBLON ISOFORM 4)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		4 / 8 ASN A 107
PRO A 108
PHE A  14
PHE A  65
 None
 1.38A 4v2zC-3odgA:
undetectable		 4v2zC-3odgA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_A_RTZA602_1
(CYTOCHROME P450 2D6)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		5 / 12 PHE A 112
PHE A 121
LEU A 120
GLY A  45
LEU A  44
 None
 1.17A 4wnwA-3odgA:
undetectable		 4wnwA-3odgA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		4 / 7 TYR A 172
ILE A  39
HIS A 144
LEU A 230
 None
 0.91A 4xo7B-3odgA:
undetectable		 4xo7B-3odgA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		4 / 7 TYR A 172
VAL A 239
ILE A  39
HIS A 144
 None
 1.18A 4xo7B-3odgA:
undetectable		 4xo7B-3odgA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWY_E_010E6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		4 / 4 THR A 246
LEU A 263
HIS A 259
GLY A  43
 XAN  A 288 (-3.8A)
None
None
None
 1.39A 5gwyA-3odgA:
undetectable		 5gwyA-3odgA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_C_CVIC301_0
(REGULATORY PROTEIN
TETR)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		5 / 12 MET A 213
MET A 212
ALA A 208
LEU A 129
CYH A 203
 None
 1.22A 5vlmC-3odgA:
undetectable		 5vlmC-3odgA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EFN_A_SAMA501_0
(SPORULATION KILLING
FACTOR MATURATION
PROTEIN SKFB)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		5 / 11 PHE A 196
SER A 224
ARG A  93
THR A 262
ALA A 266
 None
CL  A 289 ( 4.8A)
CL  A 289 ( 4.8A)
XAN  A 288 (-3.5A)
None
 1.44A 6efnA-3odgA:
undetectable		 6efnA-3odgA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_A_SAMA501_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 3odg XANTHOSINE
PHOSPHORYLASE
(Yersinia
pseudotuberculos
is) 		5 / 12 LEU A  77
GLY A  75
ILE A  25
ASP A  61
ILE A  62
 None
 0.91A 6emuA-3odgA:
undetectable		 6emuA-3odgA:
21.26