SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3odm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_B_IPBB600_0
(ODORANT-BINDING
PROTEIN)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		4 / 4 ILE A 338
MET A 529
VAL A 451
GLY A 396
 None
 1.19A 1e06B-3odmA:
undetectable		 1e06B-3odmA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_B_SNLB503_2
(MINERALOCORTICOID
RECEPTOR)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		4 / 5 LEU A 429
LEU A 430
LEU A 414
CYH A 316
 None
 1.05A 2ab2B-3odmA:
undetectable		 2ab2B-3odmA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		3 / 3 LYS A 428
ASP A 174
ASP A 305
 None
 0.94A 2br4D-3odmA:
undetectable		 2br4D-3odmA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		3 / 3 ASP A 482
TYR A 481
LYS A 465
 None
 1.16A 2othA-3odmA:
undetectable		 2othA-3odmA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_C_TOPC1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		5 / 10 ILE A 315
LEU A 436
ILE A 417
ILE A 432
PHE A 312
 None
 1.19A 2w9sC-3odmA:
undetectable		 2w9sC-3odmA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		4 / 7 GLY A 396
ALA A 397
MET A 398
LEU A 401
 None
 0.65A 2wekB-3odmA:
undetectable		 2wekB-3odmA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_1
(WNT INHIBITORY
FACTOR 1)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		4 / 6 LEU A 429
ILE A 417
MET A 410
VAL A 164
 None
 0.79A 2ygoA-3odmA:
undetectable		 2ygoA-3odmA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBZ_A_VDXA501_1
(CYTOCHROME P450-SU1)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		5 / 11 THR A  33
SER A 108
VAL A  45
ILE A  47
ALA A  26
 None
 1.17A 2zbzA-3odmA:
undetectable		 2zbzA-3odmA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		4 / 7 GLU A  44
ARG A 195
GLU A 119
SER A 118
 None
 1.01A 2zt7A-3odmA:
undetectable		 2zt7A-3odmA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_2
(PROTEASE)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		5 / 10 GLY A  38
GLY A  39
LEU A  40
VAL A  77
ILE A  71
 None
AUC  A 624 ( 4.2A)
AUC  A 624 (-4.2A)
None
None
 1.05A 3em4V-3odmA:
undetectable		 3em4V-3odmA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		5 / 10 ILE A  47
VAL A  79
ILE A 117
ILE A 101
SER A  97
 None
 1.43A 3kpbD-3odmA:
undetectable		 3kpbD-3odmA:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		4 / 6 PHE A 269
PHE A 249
HIS A 277
THR A 282
 None
 1.31A 3lb3B-3odmA:
undetectable		 3lb3B-3odmA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_1
(16S RRNA METHYLASE)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		3 / 3 ASP A 202
GLU A 126
SER A 393
 None
 0.82A 3p2kA-3odmA:
undetectable		 3p2kA-3odmA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_A_FLPA701_1
(CYCLOOXYGENASE-2)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		5 / 12 LEU A 170
VAL A 220
GLY A 222
ALA A 223
LEU A 177
 None
 1.19A 3pghA-3odmA:
undetectable		 3pghA-3odmA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_B_RGZB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		5 / 12 LEU A 429
LEU A 436
LEU A 440
ILE A 210
TYR A 481
 None
 0.92A 4a7aB-3odmA:
undetectable		 4a7aB-3odmA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		5 / 12 ILE A 313
ILE A 474
LEU A 475
GLY A 425
ILE A 417
 None
 1.15A 4o1eA-3odmA:
10.8		 4o1eA-3odmA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		4 / 4 ASN A  87
VAL A 122
THR A 127
ILE A 176
 None
 1.27A 4retA-3odmA:
undetectable		 4retA-3odmA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		4 / 4 ASN A  87
VAL A 122
THR A 127
ILE A 176
 None
 1.27A 4retC-3odmA:
undetectable		 4retC-3odmA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		5 / 12 ILE A 210
GLY A 212
SER A 211
HIS A 248
PRO A 404
 None
 1.09A 5ergB-3odmA:
undetectable		 5ergB-3odmA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		5 / 12 SER A 201
ASN A 253
ALA A 272
LEU A 273
HIS A 277
 MLI  A 901 (-2.4A)
None
None
None
None
 1.08A 5kocA-3odmA:
undetectable		 5kocA-3odmA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		5 / 12 GLY A 247
SER A 201
ASN A 253
LEU A 273
HIS A 277
 None
MLI  A 901 (-2.4A)
None
None
None
 1.05A 5kocB-3odmA:
undetectable		 5kocB-3odmA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		4 / 6 ASP A 143
ARG A 159
ASN A 139
GLN A 135
 None
 1.19A 5l6eA-3odmA:
undetectable		 5l6eA-3odmA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		4 / 4 GLN A  61
THR A  59
GLU A 103
LEU A 111
 None
 1.41A 5m66A-3odmA:
3.0		 5m66A-3odmA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODC_G_ACTG704_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		4 / 5 PRO A  81
GLN A  58
LYS A  52
GLN A  10
 None
 1.01A 5odcA-3odmA:
2.0
5odcG-3odmA:
1.8		 5odcA-3odmA:
22.86
5odcG-3odmA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		5 / 10 LEU A 429
TYR A 433
ILE A 435
PHE A 442
LEU A 477
 None
 1.22A 5y7pB-3odmA:
undetectable		 5y7pB-3odmA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_H_CHDH401_0
(BILE SALT HYDROLASE)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		5 / 10 LEU A 429
TYR A 433
ILE A 435
PHE A 442
LEU A 477
 None
 1.23A 5y7pH-3odmA:
undetectable		 5y7pH-3odmA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPL_B_PA1B605_1
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		3 / 3 ARG A 344
ARG A  93
ARG A  82
 AUC  A 607 (-3.3A)
None
MLI  A 901 (-2.8A)
 1.07A 6bplA-3odmA:
2.3
6bplB-3odmA:
undetectable		 6bplA-3odmA:
10.42
6bplB-3odmA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPL_B_PA1B605_1
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		3 / 3 ARG A 390
ARG A  93
ARG A  82
 AUC  A 607 ( 4.5A)
None
MLI  A 901 (-2.8A)
 1.03A 6bplA-3odmA:
2.3
6bplB-3odmA:
undetectable		 6bplA-3odmA:
10.42
6bplB-3odmA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		4 / 4 HIS A 491
VAL A 451
LEU A 494
ALA A 447
 None
 1.32A 6d8pB-3odmA:
3.9		 6d8pB-3odmA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_A_SAMA501_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		6 / 12 ILE A 234
GLY A 227
ASP A 178
ILE A 198
VAL A 164
ILE A 196
 None
 1.46A 6emuA-3odmA:
2.4		 6emuA-3odmA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Clostridium
perfringens) 		4 / 7 ILE A  98
GLN A  94
GLU A 133
VAL A 138
 None
 1.19A 6j20A-3odmA:
undetectable		 6j20A-3odmA:
21.22