SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3odo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_A_LPRA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3odo RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 1
(Homo
sapiens) 		5 / 12 THR A 427
HIS A 431
GLU A 428
HIS A 471
GLU A 561
 None
 0.87A 1j36A-3odoA:
3.1		 1j36A-3odoA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_B_LPRB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3odo RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 1
(Homo
sapiens) 		5 / 12 THR A 427
HIS A 431
GLU A 428
HIS A 471
GLU A 561
 None
 0.86A 1j36B-3odoA:
3.1		 1j36B-3odoA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QW6_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3odo RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 1
(Homo
sapiens) 		3 / 3 ARG A 514
VAL A 470
TRP A 507
 None
 1.15A 1qw6A-3odoA:
undetectable		 1qw6A-3odoA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QWC_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3odo RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 1
(Homo
sapiens) 		3 / 3 ARG A 514
VAL A 470
TRP A 507
 None
 1.21A 1qwcA-3odoA:
undetectable		 1qwcA-3odoA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAG_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3odo RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 1
(Homo
sapiens) 		3 / 3 ARG A 514
VAL A 470
TRP A 507
 None
 1.17A 1vagA-3odoA:
undetectable		 1vagA-3odoA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)		 3odo RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 1
(Homo
sapiens) 		4 / 6 MET A 434
VAL A 437
LEU A 438
PHE A 461
 None
 0.91A 1x8vA-3odoA:
undetectable		 1x8vA-3odoA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVI_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3odo RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 1
(Homo
sapiens) 		3 / 3 ARG A 514
VAL A 470
TRP A 507
 None
 1.22A 1zviA-3odoA:
undetectable		 1zviA-3odoA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 3odo RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 1
(Homo
sapiens) 		5 / 12 PHE A 725
ILE A 755
THR A 758
LEU A 710
LEU A 654
 None
 1.14A 2jn3A-3odoA:
undetectable		 2jn3A-3odoA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VKX_A_T3A301_1
(PROLIFERATING CELL
NUCLEAR ANTIGEN)		 3odo RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 1
(Homo
sapiens) 		4 / 6 MET A 562
LEU A 565
PRO A 569
TYR A 568
 None
 1.26A 3vkxA-3odoA:
undetectable		 3vkxA-3odoA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_C_URFC301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 3odo RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 1
(Homo
sapiens) 		3 / 3 ARG A 621
HIS A 667
ARG A 680
 None
 1.08A 5iaoC-3odoA:
undetectable		 5iaoC-3odoA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_F_URFF301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 3odo RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 1
(Homo
sapiens) 		3 / 3 ARG A 621
HIS A 667
ARG A 680
 None
 1.09A 5iaoF-3odoA:
undetectable		 5iaoF-3odoA:
17.24