SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3odp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		5 / 10 CYH A 187
LEU A 188
THR A  34
ILE A  37
ILE A 142
 None
 1.29A 1i18A-3odpA:
undetectable
1i18B-3odpA:
undetectable		 1i18A-3odpA:
13.88
1i18B-3odpA:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		5 / 10 ILE A 142
CYH A 187
LEU A 188
THR A  34
ILE A  37
 None
 1.27A 1i18A-3odpA:
undetectable
1i18B-3odpA:
undetectable		 1i18A-3odpA:
13.88
1i18B-3odpA:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		3 / 3 THR A 124
GLU A 131
ASP A 136
 None
 0.86A 1nt2A-3odpA:
3.5		 1nt2A-3odpA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TSN_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		5 / 12 SER A 186
ILE A 142
LEU A 111
GLY A  72
ALA A  65
 None
None
None
None
PO4  A 402 ( 4.6A)
 1.12A 1tsnA-3odpA:
undetectable		 1tsnA-3odpA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB926_0
(FERROCHELATASE)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		5 / 10 LEU A 140
ILE A 190
SER A 123
VAL A  71
GLY A  72
 None
None
PO4  A 402 ( 4.1A)
None
None
 1.08A 2qd4B-3odpA:
2.4		 2qd4B-3odpA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		3 / 3 ASN A 170
ARG A 116
ASP A 371
 None
 0.98A 2qe6A-3odpA:
undetectable		 2qe6A-3odpA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		5 / 10 GLU A 340
ILE A 199
GLY A 200
ARG A  32
ILE A 206
 None
 1.20A 3adsA-3odpA:
undetectable		 3adsA-3odpA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA202_1
(PROTEIN S100-A4)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		5 / 12 SER A 288
ILE A 324
GLU A 297
LEU A 301
ASP A 299
 None
 1.11A 3ko0A-3odpA:
undetectable
3ko0B-3odpA:
undetectable
3ko0C-3odpA:
undetectable
3ko0D-3odpA:
undetectable		 3ko0A-3odpA:
14.32
3ko0B-3odpA:
14.32
3ko0C-3odpA:
14.32
3ko0D-3odpA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_A_NCAA192_0
(NICOTINAMIDASE)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		5 / 11 LEU A  49
GLU A  83
PHE A 191
LEU A 110
ILE A  60
 None
 0.92A 3o94A-3odpA:
2.4		 3o94A-3odpA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_B_NCAB192_0
(NICOTINAMIDASE)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		5 / 11 LEU A  49
GLU A  83
PHE A 191
LEU A 110
ILE A  60
 None
 0.98A 3o94B-3odpA:
2.1		 3o94B-3odpA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_C_NCAC192_0
(NICOTINAMIDASE)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		5 / 11 LEU A  49
GLU A  83
PHE A 191
LEU A 110
ILE A  60
 None
 0.95A 3o94C-3odpA:
2.2		 3o94C-3odpA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_D_NCAD192_0
(NICOTINAMIDASE)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		5 / 11 LEU A  49
GLU A  83
PHE A 191
LEU A 110
ILE A  60
 None
 0.94A 3o94D-3odpA:
2.2		 3o94D-3odpA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		3 / 3 TYR A  18
ASP A 371
ASP A 171
 None
 0.94A 3ou7B-3odpA:
undetectable		 3ou7B-3odpA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_B_T1CB405_1
(TETX2 PROTEIN)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		5 / 12 PHE A 180
GLY A 178
ALA A  69
GLY A  66
ASN A  73
 None
 1.25A 3v3oB-3odpA:
undetectable		 3v3oB-3odpA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		5 / 12 VAL A 225
ILE A 334
ILE A 316
VAL A 284
LEU A 314
 None
 1.09A 3w67B-3odpA:
undetectable		 3w67B-3odpA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EVR_A_BEZA401_0
(PUTATIVE ABC
TRANSPORTER SUBUNIT,
SUBSTRATE-BINDING
COMPONENT)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		5 / 11 LEU A 184
VAL A  75
SER A  77
ALA A 238
SER A 348
 None
 1.06A 4evrA-3odpA:
3.5		 4evrA-3odpA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_1
(ANCESTRAL STEROID
RECEPTOR 2)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		5 / 12 LEU A 353
ASN A 354
LEU A 352
ALA A 355
LEU A   5
 None
 1.17A 4ltwA-3odpA:
undetectable		 4ltwA-3odpA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD4_C_AOQC4003_1
(CYTOCHROME B)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		5 / 12 GLY A  72
VAL A  71
ILE A 112
LEU A 188
ILE A 206
 None
 1.08A 4pd4C-3odpA:
undetectable		 4pd4C-3odpA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		5 / 12 LEU A 163
LEU A 140
ILE A 142
GLU A 246
ILE A  62
 None
 0.81A 4y0rA-3odpA:
undetectable		 4y0rA-3odpA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0S_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		5 / 12 LEU A 163
LEU A 140
ILE A 142
GLU A 246
ILE A  62
 None
 0.83A 4y0sA-3odpA:
undetectable		 4y0sA-3odpA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_A_ACTA404_0
(PROTON-GATED ION
CHANNEL)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		4 / 4 LEU A 347
ILE A 334
ARG A 294
TYR A 351
 None
 1.03A 4zzbA-3odpA:
1.9		 4zzbA-3odpA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA406_0
(PROTON-GATED ION
CHANNEL)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		4 / 4 LEU A 347
ILE A 334
ARG A 294
TYR A 351
 None
 1.09A 4zzcA-3odpA:
undetectable		 4zzcA-3odpA:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB406_0
(PROTON-GATED ION
CHANNEL)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		4 / 4 LEU A 347
ILE A 334
ARG A 294
TYR A 351
 None
 1.16A 4zzcB-3odpA:
1.9		 4zzcB-3odpA:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALC_L_TIQL1210_2
(ANTI-TICAGRELOR FAB
72, LIGHT CHAIN)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		4 / 8 GLY A 242
ILE A 316
GLY A 236
PHE A 241
 None
 0.85A 5alcL-3odpA:
undetectable		 5alcL-3odpA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		4 / 5 SER A  74
GLY A 178
THR A  20
GLU A  23
 None
 1.17A 5btiC-3odpA:
undetectable
5btiD-3odpA:
3.1		 5btiC-3odpA:
22.10
5btiD-3odpA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_A_SAMA501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		5 / 11 LEU A  12
GLY A 369
SER A   8
THR A  20
ALA A  21
 None
 1.11A 5o96A-3odpA:
undetectable
5o96B-3odpA:
undetectable		 5o96A-3odpA:
22.40
5o96B-3odpA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		4 / 7 ASN A  51
SER A 138
ILE A 137
PRO A 108
 None
 0.99A 5u4sA-3odpA:
2.1		 5u4sA-3odpA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Clostridium
novyi) 		3 / 3 ASN A 145
VAL A 127
HIS A 153
 None
 0.82A 6a5yD-3odpA:
undetectable		 6a5yD-3odpA:
13.04