SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3odt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKO_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 3odt PROTEIN DOA1
(Saccharomyces
cerevisiae) 		5 / 10 LEU A   9
VAL A 277
VAL A  16
GLY A 278
TRP A  45
 None
 1.42A 1fkoA-3odtA:
undetectable		 1fkoA-3odtA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA8_0
(GRAMICIDIN A)		 3odt PROTEIN DOA1
(Saccharomyces
cerevisiae) 		4 / 4 GLY A 238
VAL A 243
TRP A 265
GLY A 278
 None
 1.47A 1ng8A-3odtA:
undetectable		 1ng8A-3odtA:
3.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB8_0
(GRAMICIDIN A)		 3odt PROTEIN DOA1
(Saccharomyces
cerevisiae) 		4 / 4 GLY A 238
VAL A 243
TRP A 265
GLY A 278
 None
 1.47A 1ng8B-3odtA:
undetectable		 1ng8B-3odtA:
3.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3odt PROTEIN DOA1
(Saccharomyces
cerevisiae) 		4 / 7 LEU A  69
VAL A  60
VAL A 284
ILE A 276
 None
 0.96A 1t87B-3odtA:
undetectable		 1t87B-3odtA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3odt PROTEIN DOA1
(Saccharomyces
cerevisiae) 		5 / 11 PHE A 193
VAL A 146
GLY A 191
LEU A 164
PHE A 174
 None
 1.00A 1z11A-3odtA:
undetectable		 1z11A-3odtA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3odt PROTEIN DOA1
(Saccharomyces
cerevisiae) 		5 / 11 PHE A 193
VAL A 146
GLY A 191
LEU A 164
PHE A 174
 None
 1.01A 1z11B-3odtA:
undetectable		 1z11B-3odtA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3odt PROTEIN DOA1
(Saccharomyces
cerevisiae) 		5 / 10 PHE A 193
VAL A 146
GLY A 191
LEU A 164
PHE A 174
 None
 0.98A 1z11C-3odtA:
undetectable		 1z11C-3odtA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3odt PROTEIN DOA1
(Saccharomyces
cerevisiae) 		5 / 10 PHE A 193
VAL A 146
GLY A 191
LEU A 164
PHE A 174
 None
 1.02A 1z11D-3odtA:
undetectable		 1z11D-3odtA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 3odt PROTEIN DOA1
(Saccharomyces
cerevisiae) 		4 / 8 VAL A  27
ASP A  23
THR A  48
LEU A   9
 None
 0.86A 1z2bB-3odtA:
undetectable		 1z2bB-3odtA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_A_SAMA1300_0
(UPF0088 PROTEIN
AQ_165)		 3odt PROTEIN DOA1
(Saccharomyces
cerevisiae) 		5 / 12 ASN A  79
GLY A  73
LEU A  70
THR A  94
LEU A  95
 None
 1.09A 2egvA-3odtA:
undetectable		 2egvA-3odtA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID6_C_SAMC301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3odt PROTEIN DOA1
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 287
SER A 288
ASP A 233
ILE A 245
GLN A 255
 None
 1.12A 3id6C-3odtA:
undetectable		 3id6C-3odtA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC607_0
(ALPHA-AMYLASE)		 3odt PROTEIN DOA1
(Saccharomyces
cerevisiae) 		4 / 6 GLY A  73
ASP A  18
GLY A  55
GLY A  34
 None
 0.69A 6ag0C-3odtA:
undetectable		 6ag0C-3odtA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_A_HISA402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3odt PROTEIN DOA1
(Saccharomyces
cerevisiae) 		5 / 10 GLY A  80
LEU A  70
VAL A  22
VAL A  36
ALA A  28
 None
 0.76A 6czmA-3odtA:
undetectable
6czmC-3odtA:
undetectable		 6czmA-3odtA:
23.53
6czmC-3odtA:
23.53