SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oee'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_A_SALA3005_1
(XANTHINE
DEHYDROGENASE)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		5 / 9 LEU A 283
SER A 284
ARG A 281
LEU A 303
ALA A 277
 None
 1.42A 1fo4A-3oeeA:
undetectable		 1fo4A-3oeeA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 101
LEU A 244
ALA A 112
LEU A 113
ALA A 131
 None
 1.17A 1sa1A-3oeeA:
3.0
1sa1B-3oeeA:
undetectable		 1sa1A-3oeeA:
21.22
1sa1B-3oeeA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_B_DESB128_1
(TRANSTHYRETIN)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 481
ALA A 497
LEU A 495
SER A 492
 None
 1.00A 1tt6B-3oeeA:
undetectable		 1tt6B-3oeeA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XL6_B_SPMB3001_1
(INWARD RECTIFIER
POTASSIUM CHANNEL)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		4 / 5 TYR A 280
ALA A 242
TYR A 246
GLN A 132
 None
 1.10A 1xl6A-3oeeA:
undetectable
1xl6B-3oeeA:
undetectable		 1xl6A-3oeeA:
19.42
1xl6B-3oeeA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		4 / 8 TYR A 246
TYR A 270
PHE A 250
VAL A 206
 None
 1.18A 2fl5E-3oeeA:
undetectable
2fl5F-3oeeA:
undetectable		 2fl5E-3oeeA:
19.41
2fl5F-3oeeA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		4 / 7 THR A 331
GLY A 333
LEU A 371
PHE A 353
 None
 0.99A 2vl2B-3oeeA:
undetectable		 2vl2B-3oeeA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBZ_A_VDXA501_1
(CYTOCHROME P450-SU1)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		5 / 11 VAL A  99
SER A 129
LEU A 105
ILE A 232
ALA A 236
 None
 1.17A 2zbzA-3oeeA:
undetectable		 2zbzA-3oeeA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		5 / 12 VAL A  97
LEU A 303
ARG A 306
ALA A 253
SER A 254
 None
 1.04A 3apvA-3oeeA:
undetectable		 3apvA-3oeeA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		4 / 6 THR A 150
GLN A 188
LEU A 326
LEU A 267
 None
 1.10A 3bgdA-3oeeA:
undetectable		 3bgdA-3oeeA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_A_486A3_1
(GLUCOCORTICOID
RECEPTOR)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		5 / 12 LEU A  66
GLY A  74
VAL A  43
LEU A  54
ILE A  49
 None
 1.04A 3h52A-3oeeA:
undetectable		 3h52A-3oeeA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_G_ACTG225_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		3 / 3 PRO A 437
LEU A 438
GLN A 432
 None
 0.71A 3hznG-3oeeA:
undetectable
3hznH-3oeeA:
undetectable		 3hznG-3oeeA:
19.09
3hznH-3oeeA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LBD_A_9CRA424_1
(RETINOIC ACID
RECEPTOR GAMMA)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 154
LEU A 354
ILE A 363
GLY A 176
ALA A 179
 None
None
None
ANP  A 600 (-3.0A)
ANP  A 600 (-3.3A)
 1.28A 3lbdA-3oeeA:
undetectable		 3lbdA-3oeeA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_A_CGEA501_1
(CYTOCHROME P450 2B4)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		5 / 10 ILE A 367
ALA A 181
THR A 184
ILE A 161
VAL A 159
 None
 0.79A 3me6A-3oeeA:
undetectable		 3me6A-3oeeA:
24.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEG_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 430
LYS A 153
VAL A 451
PHE A 395
LEU A 396
 None
 1.50A 3megA-3oeeA:
undetectable		 3megA-3oeeA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_2
(POL POLYPROTEIN)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		5 / 9 ALA A 227
ASP A 226
GLY A 107
ILE A 232
LEU A 218
 None
 1.12A 3u7sB-3oeeA:
undetectable		 3u7sB-3oeeA:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_A_SALA1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		5 / 9 LEU A 283
SER A 284
ARG A 281
LEU A 303
ALA A 277
 None
 1.42A 3unaA-3oeeA:
undetectable		 3unaA-3oeeA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		5 / 9 LEU A 283
SER A 284
ARG A 281
LEU A 303
ALA A 277
 None
 1.42A 3unaB-3oeeA:
undetectable		 3unaB-3oeeA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_A_SALA1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		5 / 9 LEU A 283
SER A 284
ARG A 281
LEU A 303
ALA A 277
 None
 1.42A 3uncA-3oeeA:
undetectable		 3uncA-3oeeA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_B_SALB1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		5 / 9 LEU A 283
SER A 284
ARG A 281
LEU A 303
ALA A 277
 None
 1.41A 3uncB-3oeeA:
undetectable		 3uncB-3oeeA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 190
ARG A 486
TRP A 191
 None
 1.50A 4cpzE-3oeeA:
undetectable		 4cpzE-3oeeA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_A_VK3A202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		4 / 5 ARG A 306
TYR A 246
TYR A 280
LEU A 283
 None
 1.39A 4f8yA-3oeeA:
0.1
4f8yB-3oeeA:
0.6		 4f8yA-3oeeA:
16.63
4f8yB-3oeeA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 306
TYR A 246
TYR A 280
LEU A 283
 None
 1.39A 4f8yC-3oeeA:
undetectable
4f8yD-3oeeA:
undetectable		 4f8yC-3oeeA:
16.63
4f8yD-3oeeA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_A_1FLA201_1
(TRANSTHYRETIN)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		4 / 6 LEU A 481
ALA A 497
LEU A 495
SER A 492
 None
 1.05A 4i89A-3oeeA:
undetectable		 4i89A-3oeeA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IOM_A_FOLA608_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		4 / 7 ALA A 449
PRO A 445
LEU A 429
LEU A 455
 None
 0.77A 4iomA-3oeeA:
undetectable		 4iomA-3oeeA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JJK_A_FOLA601_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		5 / 8 ASN A 452
ALA A 449
PRO A 445
LEU A 429
LEU A 455
 None
 1.07A 4jjkA-3oeeA:
undetectable		 4jjkA-3oeeA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A303_1
(ANCESTRAL STEROID
RECEPTOR 2)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		5 / 9 THR A 503
LEU A 499
ALA A 449
GLN A 443
LEU A 474
 None
 1.29A 4ltwA-3oeeA:
undetectable		 4ltwA-3oeeA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		4 / 6 LEU A 481
ALA A 497
LEU A 495
SER A 492
 None
 1.05A 4pwjA-3oeeA:
undetectable		 4pwjA-3oeeA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z7F_C_FOLC201_0
(FOLATE ECF
TRANSPORTER)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 277
PHE A 301
THR A 342
THR A 348
LEU A 308
 None
 1.08A 4z7fC-3oeeA:
undetectable		 4z7fC-3oeeA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		4 / 6 LEU A 481
ALA A 497
LEU A 495
SER A 492
 None
 1.01A 5bojA-3oeeA:
undetectable		 5bojA-3oeeA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		5 / 12 GLY A  74
LEU A  34
LEU A 283
GLY A  63
GLY A  31
 None
 1.12A 5d4uA-3oeeA:
undetectable		 5d4uA-3oeeA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		5 / 12 GLY A  74
LEU A  34
LEU A 283
GLY A  63
GLY A  31
 None
 1.12A 5d4uB-3oeeA:
undetectable		 5d4uB-3oeeA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_C_RAPC999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		4 / 8 GLU A 459
PHE A 466
GLY A 464
THR A 503
 None
 1.00A 5flcB-3oeeA:
1.9		 5flcB-3oeeA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_C_RAPC999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		4 / 8 SER A 469
PHE A 466
GLY A 464
THR A 503
 None
 0.95A 5flcB-3oeeA:
1.9		 5flcB-3oeeA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_G_RAPG999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		4 / 8 GLU A 459
PHE A 466
GLY A 464
THR A 503
 None
 1.00A 5flcF-3oeeA:
1.8		 5flcF-3oeeA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_G_RAPG999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		4 / 8 SER A 469
PHE A 466
GLY A 464
THR A 503
 None
 0.94A 5flcF-3oeeA:
1.8		 5flcF-3oeeA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		4 / 5 ALA A  41
VAL A  73
PHE A  57
ILE A  49
 None
 0.99A 5of1A-3oeeA:
undetectable		 5of1A-3oeeA:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		4 / 5 ALA A  41
VAL A  73
PHE A  57
ILE A  49
 None
 0.95A 5of1B-3oeeA:
undetectable		 5of1B-3oeeA:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		5 / 9 LEU A 218
SER A 231
GLY A 107
ILE A 232
ILE A 185
 None
 1.21A 6ebpA-3oeeA:
undetectable		 6ebpA-3oeeA:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		5 / 10 LEU A 218
SER A 231
GLY A 107
ILE A 232
ILE A 185
 None
 1.23A 6ebpB-3oeeA:
undetectable		 6ebpB-3oeeA:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_C_SAMC301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 354
ILE A 352
VAL A 373
VAL A 159
ILE A 367
 None
 0.96A 6emuC-3oeeA:
undetectable		 6emuC-3oeeA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 3oee ATP SYNTHASE SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 273
ASP A 271
ALA A 252
LEU A 307
LEU A 323
 None
MG  A 700 ( 3.6A)
None
None
None
 1.18A 6ew0F-3oeeA:
undetectable		 6ew0F-3oeeA:
11.21