SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oep'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_1_T441128_1
(TRANSTHYRETIN)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 5 LEU A 321
GLU A 303
ALA A 285
LEU A 283
None
1.03A 1eta1-3oepA:
undetectable
1eta1-3oepA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_2_T442129_1
(TRANSTHYRETIN)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 5 LEU A 321
GLU A 303
ALA A 285
LEU A 283
None
1.07A 1eta2-3oepA:
undetectable
1eta2-3oepA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_1_T441128_1
(TRANSTHYRETIN)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 6 LEU A 321
GLU A 303
ALA A 285
LEU A 283
None
1.02A 1etb1-3oepA:
undetectable
1etb1-3oepA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 8 VAL A 225
LEU A 223
PRO A 281
VAL A 336
None
0.98A 1fduB-3oepA:
undetectable
1fduB-3oepA:
25.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
5 / 10 PRO A 121
GLY A 122
LEU A 346
PHE A 345
GLY A 242
None
1.27A 1h4oA-3oepA:
undetectable
1h4oB-3oepA:
undetectable
1h4oA-3oepA:
17.38
1h4oB-3oepA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
5 / 10 PRO A 186
PRO A 121
GLY A 122
LEU A 346
PHE A 345
None
1.31A 1h4oA-3oepA:
undetectable
1h4oB-3oepA:
undetectable
1h4oA-3oepA:
17.38
1h4oB-3oepA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_D_BEZD1162_0
(PEROXIREDOXIN 5)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
5 / 9 PRO A 186
PRO A 121
GLY A 122
LEU A 346
PHE A 345
None
1.36A 1h4oD-3oepA:
undetectable
1h4oD-3oepA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_F_BEZF1162_0
(PEROXIREDOXIN 5)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
5 / 9 PRO A 186
PRO A 121
GLY A 122
LEU A 346
PHE A 345
None
1.35A 1h4oF-3oepA:
undetectable
1h4oF-3oepA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
5 / 8 PRO A 186
PRO A 121
GLY A 122
LEU A 346
PHE A 345
None
1.30A 1h4oG-3oepA:
undetectable
1h4oG-3oepA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_H_BEZH1162_0
(PEROXIREDOXIN 5)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
5 / 9 PRO A 186
PRO A 121
GLY A 122
LEU A 346
PHE A 345
None
1.35A 1h4oH-3oepA:
undetectable
1h4oH-3oepA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HD2_A_BEZA201_0
(PEROXIREDOXIN 5
RESIDUES 54-214)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
5 / 9 PRO A 186
PRO A 121
GLY A 122
LEU A 346
PHE A 345
None
1.31A 1hd2A-3oepA:
undetectable
1hd2A-3oepA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_C_T44C128_1
(TRANSTHYRETIN)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
5 / 11 ALA A 291
LEU A 321
GLU A 303
ALA A 285
LEU A 283
None
1.23A 1ictA-3oepA:
undetectable
1ictC-3oepA:
undetectable
1ictA-3oepA:
13.32
1ictC-3oepA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_A_T44A128_1
(TRANSTHYRETIN)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
5 / 10 ALA A 291
LEU A 321
GLU A 303
ALA A 285
LEU A 283
None
1.10A 1ie4A-3oepA:
undetectable
1ie4C-3oepA:
undetectable
1ie4A-3oepA:
13.96
1ie4C-3oepA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_A_T44A128_1
(TRANSTHYRETIN)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
5 / 10 LEU A 321
GLU A 303
ALA A 285
LEU A 283
ALA A 291
None
0.99A 1ie4A-3oepA:
undetectable
1ie4C-3oepA:
undetectable
1ie4A-3oepA:
13.96
1ie4C-3oepA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGS_A_SALA256_1
(MULTIPLE ANTIBIOTIC
RESISTANCE PROTEIN
MARR)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 7 VAL A 366
LEU A 286
THR A 284
LEU A 283
None
0.77A 1jgsA-3oepA:
undetectable
1jgsA-3oepA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA442_1
(ALPHA AMYLASE)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
5 / 11 GLY A 243
PHE A 187
GLY A 118
GLY A 355
ASP A 352
None
1.11A 1mxgA-3oepA:
undetectable
1mxgA-3oepA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 7 LEU A 425
LEU A 392
LEU A 457
GLY A 422
None
0.80A 1n13D-3oepA:
undetectable
1n13E-3oepA:
undetectable
1n13D-3oepA:
10.85
1n13E-3oepA:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_B_BEZB201_0
(PEROXIREDOXIN 5)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
5 / 9 PRO A 186
PRO A 121
GLY A 122
LEU A 346
PHE A 345
None
1.36A 1oc3B-3oepA:
undetectable
1oc3B-3oepA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_B_T44B602_1
(TRANSTHYRETIN)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 7 LEU A 321
GLU A 303
ALA A 285
ALA A 291
None
0.85A 1sn0B-3oepA:
undetectable
1sn0D-3oepA:
undetectable
1sn0B-3oepA:
13.44
1sn0D-3oepA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_1
(TRANSTHYRETIN)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 6 LEU A 321
GLU A 303
ALA A 285
LEU A 283
None
0.98A 1sn5A-3oepA:
undetectable
1sn5A-3oepA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_2
(TRANSTHYRETIN)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 8 LEU A 321
GLU A 303
ALA A 285
LEU A 283
None
0.98A 1sn5C-3oepA:
undetectable
1sn5C-3oepA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1URM_A_BEZA201_0
(PEROXIREDOXIN 5)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
5 / 9 PRO A 186
PRO A 121
GLY A 122
LEU A 346
PHE A 345
None
1.32A 1urmA-3oepA:
undetectable
1urmA-3oepA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
5 / 10 LEU A 321
ALA A 285
ALA A 337
LEU A 264
PHE A 313
None
None
GOL  A 500 ( 3.8A)
None
None
1.15A 1xp0A-3oepA:
undetectable
1xp0A-3oepA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 7 THR A 204
PRO A 205
HIS A 148
GLY A 172
None
1.02A 2ddwB-3oepA:
undetectable
2ddwB-3oepA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_B_ADNB2002_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 6 ARG A  30
ASN A  18
PRO A  41
ALA A  21
None
1.36A 2ejfB-3oepA:
undetectable
2ejfB-3oepA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
3 / 3 ARG A  19
GLY A 192
PRO A 191
None
0.77A 2hreD-3oepA:
undetectable
2hreD-3oepA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
3 / 3 ARG A 414
GLY A 427
PRO A 428
GOL  A 502 (-3.5A)
None
None
0.59A 2hreD-3oepA:
undetectable
2hreD-3oepA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_B_017B203_1
(HIV-1 PROTEASE)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 7 GLU A 370
PRO A 374
ARG A 373
GLY A 339
None
GOL  A 500 ( 4.7A)
None
None
0.98A 2hs1B-3oepA:
undetectable
2hs1B-3oepA:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_B_LDPB502_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 5 GLN A 156
PHE A 125
PHE A 123
GLY A 167
None
GOL  A 501 (-4.8A)
None
GOL  A 501 ( 4.9A)
1.33A 2qmzA-3oepA:
undetectable
2qmzB-3oepA:
undetectable
2qmzA-3oepA:
18.48
2qmzB-3oepA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 7 GLY A 166
GLY A 465
PHE A 125
PHE A 123
GOL  A 501 (-3.2A)
None
GOL  A 501 (-4.8A)
None
0.78A 2qwxA-3oepA:
undetectable
2qwxB-3oepA:
undetectable
2qwxA-3oepA:
18.69
2qwxB-3oepA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UZ2_A_ACTA1123_0
(XENAVIDIN)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 7 LEU A 133
TYR A 112
THR A 157
VAL A 152
None
0.99A 2uz2A-3oepA:
undetectable
2uz2A-3oepA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X8O_A_OINA1314_1
(CHOLINE-BINDING
PROTEIN F)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 5 ASP A 254
ARG A 331
TYR A 333
GLU A 275
None
1.19A 2x8oA-3oepA:
undetectable
2x8oA-3oepA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZD1_A_T27A557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
5 / 12 LEU A  22
VAL A  45
TYR A 115
TYR A  43
PRO A 439
None
1.49A 2zd1A-3oepA:
4.0
2zd1A-3oepA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 7 ILE A 489
LEU A 392
PHE A 491
ARG A 452
None
0.97A 2zxwN-3oepA:
undetectable
2zxwW-3oepA:
undetectable
2zxwN-3oepA:
21.17
2zxwW-3oepA:
7.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AV6_A_SAMA1_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
5 / 12 GLY A 158
LEU A  98
ASN A 169
ALA A 151
VAL A 150
None
1.07A 3av6A-3oepA:
undetectable
3av6A-3oepA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1100_1
(SERUM ALBUMIN)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 4 LEU A  46
ARG A  30
LEU A  29
ALA A  23
None
1.10A 3b9mA-3oepA:
undetectable
3b9mA-3oepA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
3 / 3 GLY A 118
GLY A 243
GLY A 246
None
0.40A 3bogD-3oepA:
undetectable
3bogD-3oepA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_1
(PCZA361.24)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
3 / 3 ARG A 259
GLU A 275
ASP A 419
None
0.68A 3g2oA-3oepA:
undetectable
3g2oA-3oepA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
5 / 12 VAL A 114
LEU A 126
LEU A 117
PHE A 197
ILE A  80
None
1.27A 3kk6B-3oepA:
undetectable
3kk6B-3oepA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
3 / 3 ASP A 254
SER A 257
ARG A 384
None
0.52A 3loqA-3oepA:
undetectable
3loqA-3oepA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6W_A_SAMA465_0
(RRNA METHYLASE)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
5 / 12 GLY A 318
VAL A 225
PRO A 281
VAL A 234
LEU A 274
None
1.02A 3m6wA-3oepA:
undetectable
3m6wA-3oepA:
27.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_A_SAMA258_0
(PUTATIVE
METHYLTRANSFERASE)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
5 / 12 ARG A 384
GLN A 383
GLY A 295
LEU A 334
ALA A 258
None
1.19A 3sxjA-3oepA:
undetectable
3sxjA-3oepA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_B_SAMB258_0
(PUTATIVE
METHYLTRANSFERASE)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
5 / 12 ARG A 384
GLN A 383
GLY A 295
LEU A 334
ALA A 258
None
1.19A 3sxjB-3oepA:
undetectable
3sxjB-3oepA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 8 VAL A 445
LEU A 408
LEU A 394
ILE A 489
None
0.91A 3u5kC-3oepA:
undetectable
3u5kC-3oepA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_D_08JD4_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 8 VAL A 445
LEU A 408
LEU A 394
ILE A 489
None
0.86A 3u5kD-3oepA:
undetectable
3u5kD-3oepA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_B_017B202_1
(PROTEASE)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 7 PRO A 308
ARG A 326
GLY A 327
PRO A 328
None
1.30A 3ucbB-3oepA:
undetectable
3ucbB-3oepA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_2
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 4 PRO A  33
LEU A 241
HIS A 244
LEU A 117
None
1.42A 3vw7A-3oepA:
undetectable
3vw7A-3oepA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_A_TYLA1188_1
(BROMODOMAIN
CONTAINING 2)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 5 VAL A 445
LEU A 408
LEU A 394
ILE A 489
None
0.95A 4a9jA-3oepA:
undetectable
4a9jA-3oepA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 5 VAL A 445
LEU A 408
LEU A 394
ILE A 489
None
0.92A 4a9jB-3oepA:
undetectable
4a9jB-3oepA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KFB_A_T27A607_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H,
EXORIBONUCLEA P66 RT)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
5 / 12 LEU A  22
VAL A  45
TYR A 115
TYR A  43
PRO A 439
None
1.50A 4kfbA-3oepA:
4.5
4kfbA-3oepA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
5 / 12 ALA A 335
TYR A 333
PHE A 298
PHE A 293
SER A 257
None
1.22A 4mm4A-3oepA:
undetectable
4mm4A-3oepA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_1
(TRANSPORTER)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
5 / 12 ALA A 335
TYR A 333
PHE A 298
PHE A 293
SER A 257
None
1.21A 4mm4B-3oepA:
undetectable
4mm4B-3oepA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z3O_F_MFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT
B,PARE30-PARC55
FUSED TOPO IV FROM
S. PNEUMONIAE
E-SITE DNA)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 5 ARG A 420
ARG A 359
GLY A 358
GLU A 212
None
1.10A 4z3oA-3oepA:
5.5
4z3oB-3oepA:
5.5
4z3oA-3oepA:
20.37
4z3oB-3oepA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_E_ACTE403_0
(PROTON-GATED ION
CHANNEL)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
3 / 3 ARG A 420
TYR A 333
GLU A 275
None
0.68A 4zzbE-3oepA:
undetectable
4zzbE-3oepA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 6 ARG A 359
GLY A 358
GLU A 212
ARG A 420
None
1.05A 5btaA-3oepA:
5.3
5btaB-3oepA:
undetectable
5btaC-3oepA:
5.6
5btaA-3oepA:
23.37
5btaB-3oepA:
20.53
5btaC-3oepA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 6 ARG A 420
ARG A 359
GLY A 358
GLU A 212
None
1.03A 5btcA-3oepA:
5.4
5btcC-3oepA:
5.2
5btcD-3oepA:
undetectable
5btcA-3oepA:
23.37
5btcC-3oepA:
23.37
5btcD-3oepA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 6 ARG A 359
GLY A 358
GLU A 212
ARG A 420
None
1.03A 5btcA-3oepA:
5.3
5btcB-3oepA:
undetectable
5btcC-3oepA:
5.2
5btcA-3oepA:
23.37
5btcB-3oepA:
20.53
5btcC-3oepA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
5 / 7 VAL A 103
LEU A 133
GLU A 101
ALA A 102
LEU A  89
None
1.37A 5jq7A-3oepA:
undetectable
5jq7A-3oepA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
5 / 12 LEU A 361
LEU A 214
LEU A 283
PRO A 218
LEU A 286
None
1.16A 5og9B-3oepA:
undetectable
5og9B-3oepA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_2
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 4 VAL A 366
LEU A 223
LEU A 283
ASP A 232
None
1.50A 5xv7A-3oepA:
undetectable
5xv7A-3oepA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus)
4 / 5 PRO A 281
VAL A 225
GLY A 358
VAL A 234
None
1.08A 6ak3B-3oepA:
undetectable
6ak3B-3oepA:
9.73