SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oet'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3oet ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE
(Salmonella
enterica) 		5 / 10 LEU A 304
ASP A 305
LEU A 309
THR A 299
ILE A 298
 None
 1.26A 1i18A-3oetA:
undetectable
1i18B-3oetA:
undetectable		 1i18A-3oetA:
15.30
1i18B-3oetA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3oet ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE
(Salmonella
enterica) 		5 / 10 THR A 299
ILE A 298
LEU A 304
ASP A 305
LEU A 309
 None
 1.27A 1i18A-3oetA:
undetectable
1i18B-3oetA:
undetectable		 1i18A-3oetA:
15.30
1i18B-3oetA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 3oet ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE
(Salmonella
enterica) 		5 / 10 THR A  64
LEU A  77
VAL A  72
THR A  47
VAL A  43
 None
 1.28A 1o76A-3oetA:
undetectable		 1o76A-3oetA:
26.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_E_H4BE1004_1
(HYPOTHETICAL PROTEIN
PH0634)		 3oet ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE
(Salmonella
enterica) 		5 / 11 PHE A  16
LEU A  19
VAL A 284
THR A 268
THR A 267
 None
 1.50A 2dttD-3oetA:
undetectable
2dttE-3oetA:
undetectable		 2dttD-3oetA:
16.62
2dttE-3oetA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3oet ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE
(Salmonella
enterica) 		5 / 12 LEU A 368
LEU A 138
ILE A 140
ALA A 102
ILE A 204
 None
 1.13A 2h42C-3oetA:
undetectable		 2h42C-3oetA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		 3oet ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE
(Salmonella
enterica) 		4 / 6 LEU A 103
LEU A 106
ILE A 119
ARG A 117
 None
 0.94A 2rlfB-3oetA:
undetectable
2rlfC-3oetA:
undetectable		 2rlfB-3oetA:
11.24
2rlfC-3oetA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_2
(THYROXINE-BINDING
GLOBULIN)		 3oet ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE
(Salmonella
enterica) 		3 / 3 LEU A 138
ARG A 134
ILE A 140
 None
 0.48A 2xn5B-3oetA:
undetectable		 2xn5B-3oetA:
7.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3oet ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE
(Salmonella
enterica) 		4 / 6 LEU A 103
ARG A 130
THR A 133
LEU A 135
 None
 1.09A 2zxwA-3oetA:
undetectable
2zxwJ-3oetA:
undetectable		 2zxwA-3oetA:
22.37
2zxwJ-3oetA:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)		 3oet ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE
(Salmonella
enterica) 		3 / 3 LYS A 179
ARG A 208
LYS A  48
 None
 1.41A 3okxA-3oetA:
undetectable		 3okxA-3oetA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3M_A_DLUA398_1
(PFV INTEGRASE)		 3oet ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE
(Salmonella
enterica) 		4 / 8 GLY A 257
TYR A 317
GLU A 261
ARG A 321
 NAD  A 379 (-3.6A)
None
None
None
 1.04A 3s3mA-3oetA:
undetectable		 3s3mA-3oetA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX5_B_MIYB1103_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3oet ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE
(Salmonella
enterica) 		5 / 12 PHE A  84
GLY A  83
ASN A  60
ALA A 273
VAL A 270
 None
 1.18A 4dx5B-3oetA:
undetectable		 4dx5B-3oetA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_D_ACTD504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3oet ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE
(Salmonella
enterica) 		3 / 3 GLY A  56
SER A  55
TRP A  76
 None
 0.92A 4e7cD-3oetA:
undetectable		 4e7cD-3oetA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MGH_A_ACTA1320_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 3oet ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE
(Salmonella
enterica) 		4 / 5 VAL A 170
LEU A 103
ILE A 204
LEU A 203
 None
 0.80A 4mghA-3oetA:
3.3		 4mghA-3oetA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_B_SAMB603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3oet ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE
(Salmonella
enterica) 		5 / 9 LEU A 103
VAL A 230
THR A 252
ILE A 255
ASP A 232
 None
None
None
None
NAD  A 379 (-4.1A)
 1.49A 4pcuA-3oetA:
0.3
4pcuB-3oetA:
1.6		 4pcuA-3oetA:
21.25
4pcuB-3oetA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_0
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 3oet ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE
(Salmonella
enterica) 		5 / 12 GLY A  81
ALA A  80
VAL A  49
TRP A  76
GLN A  79
 None
 1.47A 4ryaA-3oetA:
undetectable		 4ryaA-3oetA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3oet ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE
(Salmonella
enterica) 		5 / 12 PHE A  84
GLY A  83
ASN A  60
ALA A 273
VAL A 270
 None
 1.15A 4u8vB-3oetA:
undetectable		 4u8vB-3oetA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U95_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3oet ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE
(Salmonella
enterica) 		5 / 12 PHE A  84
GLY A  83
ASN A  60
ALA A 273
VAL A 270
 None
 1.16A 4u95B-3oetA:
undetectable		 4u95B-3oetA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT8_A_TMQA302_1
(RV2671)		 3oet ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE
(Salmonella
enterica) 		5 / 12 ILE A 255
GLY A 257
ALA A 256
ASP A 232
THR A 252
 None
NAD  A 379 (-3.6A)
NAD  A 379 (-3.8A)
NAD  A 379 (-4.1A)
None
 1.10A 4xt8A-3oetA:
undetectable		 4xt8A-3oetA:
25.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODH_G_ACTG710_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3oet ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE
(Salmonella
enterica) 		4 / 4 ARG A 280
ILE A 278
TYR A 274
ILE A   3
 None
 1.49A 5odhG-3oetA:
3.9		 5odhG-3oetA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 3oet ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE
(Salmonella
enterica) 		5 / 12 ILE A 119
GLY A 123
GLY A 128
THR A 142
LEU A 143
 None
NAD  A 379 (-3.3A)
None
None
None
 0.85A 5twjA-3oetA:
undetectable		 5twjA-3oetA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_D_SAMD201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 3oet ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE
(Salmonella
enterica) 		5 / 11 ILE A 119
GLY A 123
GLY A 128
THR A 142
LEU A 143
 None
NAD  A 379 (-3.3A)
None
None
None
 0.89A 5twjD-3oetA:
2.0		 5twjD-3oetA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIH_A_8CVA201_1
(DIHYDROFOLATE
REDUCTASE)		 3oet ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE
(Salmonella
enterica) 		4 / 8 ILE A 119
ALA A 168
LEU A 203
ILE A 121
 None
 0.92A 5uihA-3oetA:
undetectable		 5uihA-3oetA:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CJK_C_ACTC301_0
(IMMUNOGLOBULIN FAB
LIGHT CHAIN)		 3oet ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE
(Salmonella
enterica) 		4 / 4 VAL A 230
GLY A 251
ASP A 323
ASP A 322
 None
 1.18A 6cjkC-3oetA:
undetectable		 6cjkC-3oetA:
19.54