SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3of3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		3 / 4 LYS A 209
ALA A 210
MET A 147
 None
 1.07A 1hk3A-3of3A:
undetectable		 1hk3A-3of3A:
17.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_A_ADNA1260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 10 ARG A 101
VAL A 192
GLU A 193
MET A 194
GLU A 195
ASP A 218
 PO4  A 501 (-2.8A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.1A)
 0.50A 1jdvA-3of3A:
32.7
1jdvD-3of3A:
32.7		 1jdvA-3of3A:
30.77
1jdvD-3of3A:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_B_ADNB2260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 10 ARG A 101
VAL A 192
GLU A 193
MET A 194
GLU A 195
ASP A 218
 PO4  A 501 (-2.8A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.1A)
 0.51A 1jdvB-3of3A:
32.5
1jdvC-3of3A:
33.0		 1jdvB-3of3A:
30.77
1jdvC-3of3A:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_D_ADND3260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 10 ARG A 101
VAL A 192
GLU A 193
MET A 194
GLU A 195
ASP A 218
 PO4  A 501 (-2.8A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.1A)
 0.48A 1jdvA-3of3A:
32.7
1jdvD-3of3A:
32.7		 1jdvA-3of3A:
30.77
1jdvD-3of3A:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 12 ARG A 101
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
ASP A 218
 PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
DIH  A 500 (-3.1A)
 0.54A 1jdvE-3of3A:
32.6
1jdvF-3of3A:
33.1		 1jdvE-3of3A:
30.77
1jdvF-3of3A:
30.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 10 THR A  63
GLY A  61
VAL A  51
ALA A  21
ILE A  19
 None
 0.98A 1likA-3of3A:
undetectable		 1likA-3of3A:
24.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 11 ARG A 101
GLY A 191
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.26A 1odiA-3of3A:
25.9		 1odiA-3of3A:
34.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 11 MET A  78
ARG A 101
GLY A 106
GLU A 193
MET A 194
GLU A 195
SER A 217
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
None
 0.43A 1odiA-3of3A:
25.9		 1odiA-3of3A:
34.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 11 MET A  78
ARG A 101
GLY A 106
GLU A 193
MET A 194
GLU A 195
SER A 217
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
None
 0.45A 1odiB-3of3A:
35.3		 1odiB-3of3A:
34.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 11 MET A  78
ARG A 101
GLY A 106
GLU A 193
MET A 194
GLU A 195
SER A 217
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
None
 0.41A 1odiC-3of3A:
35.6		 1odiC-3of3A:
34.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 11 MET A  78
ARG A 101
GLY A 106
GLU A 193
MET A 194
GLU A 195
SER A 217
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
None
 0.46A 1odiD-3of3A:
35.4		 1odiD-3of3A:
34.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 11 MET A  78
ARG A 101
GLY A 106
GLU A 193
MET A 194
GLU A 195
SER A 217
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
None
 0.42A 1odiE-3of3A:
35.4		 1odiE-3of3A:
34.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 11 MET A  78
ARG A 101
GLY A 106
GLU A 193
MET A 194
GLU A 195
SER A 217
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
None
 0.43A 1odiF-3of3A:
35.4		 1odiF-3of3A:
34.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PG2_A_ADNA552_1
(METHIONYL-TRNA
SYNTHETASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 11 GLU A 195
GLY A  77
HIS A  76
TYR A  86
VAL A  87
 DIH  A 500 (-2.9A)
None
None
None
None
 1.10A 1pg2A-3of3A:
undetectable		 1pg2A-3of3A:
20.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_A_ADNA1245_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 9 MET A  78
ARG A 101
SER A 104
GLY A 106
GLU A 193
MET A 194
GLU A 195
SER A 217
ASP A 218
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
DIH  A 500 (-3.1A)
 0.53A 1pk7A-3of3A:
39.6		 1pk7A-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 8 ARG A 101
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
ILE A 220
 PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
None
 0.56A 1pk7B-3of3A:
40.4		 1pk7B-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 8 ARG A 101
GLY A 191
VAL A 192
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.38A 1pk7B-3of3A:
40.4		 1pk7B-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 10 ARG A 101
GLY A 191
VAL A 192
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.44A 1pk7C-3of3A:
22.1		 1pk7C-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		10 / 10 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
ASP A 218
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
DIH  A 500 (-3.1A)
 0.27A 1pk7C-3of3A:
22.1		 1pk7C-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 10 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.42A 1pk9A-3of3A:
39.9		 1pk9A-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		10 / 10 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
ASP A 218
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
DIH  A 500 (-3.1A)
 0.37A 1pk9A-3of3A:
39.9		 1pk9A-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 9 ARG A 101
GLY A 191
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.12A 1pk9B-3of3A:
40.2		 1pk9B-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 9 MET A  78
ARG A 101
SER A 104
GLY A 106
GLU A 193
MET A 194
GLU A 195
SER A 217
ASP A 218
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
DIH  A 500 (-3.1A)
 0.40A 1pk9B-3of3A:
40.2		 1pk9B-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		11 / 11 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
ASP A 218
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
DIH  A 500 (-3.1A)
None
 0.27A 1pk9C-3of3A:
43.8		 1pk9C-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		10 / 10 MET A  78
ARG A 101
SER A 104
GLY A 106
GLU A 193
MET A 194
GLU A 195
SER A 217
ASP A 218
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
DIH  A 500 (-3.1A)
None
 0.47A 1pw7A-3of3A:
39.9		 1pw7A-3of3A:
79.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 9 ARG A 101
GLY A 191
VAL A 192
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.45A 1pw7B-3of3A:
40.8		 1pw7B-3of3A:
79.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 9 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
None
 0.34A 1pw7B-3of3A:
40.8		 1pw7B-3of3A:
79.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_C_RABC647_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 9 MET A  78
SER A 104
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
ASP A 218
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
DIH  A 500 (-3.1A)
None
 0.37A 1pw7C-3of3A:
41.2		 1pw7C-3of3A:
79.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_B_T44B602_1
(TRANSTHYRETIN)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		4 / 7 LYS A  40
LEU A  37
GLU A  44
ALA A  39
 None
 1.15A 1sn0B-3of3A:
undetectable
1sn0D-3of3A:
undetectable		 1sn0B-3of3A:
21.46
1sn0D-3of3A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_B_URFB999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		4 / 7 MET A 238
ALA A 242
ILE A 213
PHE A 235
 None
 0.93A 1upfB-3of3A:
undetectable		 1upfB-3of3A:
23.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.34A 1vhwA-3of3A:
42.5
1vhwD-3of3A:
42.5		 1vhwA-3of3A:
98.77
1vhwD-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 11 GLY A 191
VAL A 192
GLU A 193
GLU A 195
ARG A  38
 None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-2.9A)
PO4  A 501 (-2.9A)
 1.41A 1vhwA-3of3A:
42.5
1vhwD-3of3A:
42.5		 1vhwA-3of3A:
98.77
1vhwD-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 11 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
None
 0.26A 1vhwA-3of3A:
42.5
1vhwD-3of3A:
42.5		 1vhwA-3of3A:
98.77
1vhwD-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_B_ADNB252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 9 ARG A 101
GLY A 191
VAL A 192
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.34A 1vhwB-3of3A:
42.6
1vhwF-3of3A:
42.4		 1vhwB-3of3A:
98.77
1vhwF-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_B_ADNB252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		7 / 9 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
MET A 194
GLU A 195
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 0.26A 1vhwB-3of3A:
42.6
1vhwF-3of3A:
42.4		 1vhwB-3of3A:
98.77
1vhwF-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.34A 1vhwC-3of3A:
42.6
1vhwE-3of3A:
42.3		 1vhwC-3of3A:
98.77
1vhwE-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 11 GLY A 191
VAL A 192
GLU A 193
GLU A 195
ARG A  38
 None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-2.9A)
PO4  A 501 (-2.9A)
 1.41A 1vhwC-3of3A:
42.6
1vhwE-3of3A:
42.3		 1vhwC-3of3A:
98.77
1vhwE-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 11 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
None
 0.25A 1vhwC-3of3A:
42.6
1vhwE-3of3A:
42.3		 1vhwC-3of3A:
98.77
1vhwE-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 11 ARG A  38
GLY A 191
VAL A 192
GLU A 193
GLU A 195
 PO4  A 501 (-2.9A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-2.9A)
 1.41A 1vhwA-3of3A:
42.5
1vhwD-3of3A:
42.5		 1vhwA-3of3A:
98.77
1vhwD-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.33A 1vhwA-3of3A:
42.5
1vhwD-3of3A:
42.5		 1vhwA-3of3A:
98.77
1vhwD-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 11 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
None
 0.26A 1vhwA-3of3A:
42.5
1vhwD-3of3A:
42.5		 1vhwA-3of3A:
98.77
1vhwD-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 11 ARG A  38
GLY A 191
VAL A 192
GLU A 193
GLU A 195
 PO4  A 501 (-2.9A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-2.9A)
 1.41A 1vhwC-3of3A:
42.6
1vhwE-3of3A:
42.3		 1vhwC-3of3A:
98.77
1vhwE-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.34A 1vhwC-3of3A:
42.6
1vhwE-3of3A:
42.3		 1vhwC-3of3A:
98.77
1vhwE-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 11 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
None
 0.23A 1vhwC-3of3A:
42.6
1vhwE-3of3A:
42.3		 1vhwC-3of3A:
98.77
1vhwE-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_F_ADNF252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 10 ARG A  38
GLY A 191
VAL A 192
GLU A 193
GLU A 195
 PO4  A 501 (-2.9A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-2.9A)
 1.40A 1vhwB-3of3A:
42.6
1vhwF-3of3A:
42.4		 1vhwB-3of3A:
98.77
1vhwF-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_F_ADNF252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 10 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.34A 1vhwB-3of3A:
42.6
1vhwF-3of3A:
42.4		 1vhwB-3of3A:
98.77
1vhwF-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_F_ADNF252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 10 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 0.25A 1vhwB-3of3A:
42.6
1vhwF-3of3A:
42.4		 1vhwB-3of3A:
98.77
1vhwF-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 10 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.44A 1z35A-3of3A:
37.8		 1z35A-3of3A:
55.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 10 MET A  78
ARG A 101
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
 0.46A 1z35A-3of3A:
37.8		 1z35A-3of3A:
55.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 9 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.42A 1z37A-3of3A:
38.1		 1z37A-3of3A:
55.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 9 MET A  78
ARG A 101
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
 0.43A 1z37A-3of3A:
38.1		 1z37A-3of3A:
55.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.44A 2ac7A-3of3A:
36.0
2ac7B-3of3A:
36.1		 2ac7A-3of3A:
54.62
2ac7B-3of3A:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 11 MET A  78
ARG A 101
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
ASP A 218
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.1A)
 0.43A 2ac7A-3of3A:
36.0
2ac7B-3of3A:
36.1		 2ac7A-3of3A:
54.62
2ac7B-3of3A:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.44A 2ac7A-3of3A:
36.0
2ac7B-3of3A:
36.1		 2ac7A-3of3A:
54.62
2ac7B-3of3A:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 11 MET A  78
ARG A 101
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
ASP A 218
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.1A)
 0.43A 2ac7A-3of3A:
36.0
2ac7B-3of3A:
36.1		 2ac7A-3of3A:
54.62
2ac7B-3of3A:
54.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_B_THRB402_0
(ASPARTOKINASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 9 ILE A 112
ILE A 220
ASP A 185
GLY A 191
ALA A 107
 None
 1.28A 2dtjA-3of3A:
undetectable
2dtjB-3of3A:
undetectable		 2dtjA-3of3A:
23.72
2dtjB-3of3A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		4 / 7 PHE A  26
TYR A  94
VAL A  56
ASP A  25
 None
 0.97A 2qbnA-3of3A:
undetectable		 2qbnA-3of3A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_2
(GLUCOCORTICOID
RECEPTOR 2)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		3 / 3 MET A 194
MET A 180
PHE A 173
 DIH  A 500 (-3.8A)
None
DIH  A 500 (-4.3A)
 1.14A 3gn8A-3of3A:
undetectable		 3gn8A-3of3A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 10 VAL A 190
GLY A 188
VAL A 162
ASN A 166
GLY A 165
 None
 1.17A 3km6A-3of3A:
undetectable		 3km6A-3of3A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 9 VAL A 190
GLY A 188
VAL A 162
ASN A 166
GLY A 165
 None
 1.20A 3kmoA-3of3A:
undetectable		 3kmoA-3of3A:
20.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_A_ADNA251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		7 / 9 MET A  78
ARG A 101
SER A 104
VAL A 192
GLU A 193
MET A 194
GLU A 195
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 0.58A 3u40A-3of3A:
36.3
3u40F-3of3A:
34.0		 3u40A-3of3A:
46.12
3u40F-3of3A:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_B_ADNB251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		7 / 10 MET A  78
ARG A 101
SER A 104
VAL A 192
GLU A 193
MET A 194
GLU A 195
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 0.50A 3u40B-3of3A:
35.7
3u40C-3of3A:
17.7		 3u40B-3of3A:
46.12
3u40C-3of3A:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_C_ADNC251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 12 GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.44A 3u40B-3of3A:
35.7
3u40C-3of3A:
17.7		 3u40B-3of3A:
46.12
3u40C-3of3A:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_C_ADNC251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 12 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
ASP A 218
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.1A)
 0.47A 3u40B-3of3A:
35.7
3u40C-3of3A:
17.7		 3u40B-3of3A:
46.12
3u40C-3of3A:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_D_ADND251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 11 GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.41A 3u40D-3of3A:
36.3
3u40E-3of3A:
35.7		 3u40D-3of3A:
46.12
3u40E-3of3A:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_D_ADND251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 11 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
ASP A 218
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.1A)
 0.45A 3u40D-3of3A:
36.3
3u40E-3of3A:
35.7		 3u40D-3of3A:
46.12
3u40E-3of3A:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 12 GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.45A 3u40D-3of3A:
36.3
3u40E-3of3A:
35.7		 3u40D-3of3A:
46.12
3u40E-3of3A:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 12 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
ASP A 218
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.1A)
 0.45A 3u40D-3of3A:
36.3
3u40E-3of3A:
35.7		 3u40D-3of3A:
46.12
3u40E-3of3A:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_F_ADNF251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 10 MET A  78
ARG A 101
SER A 104
VAL A 192
GLU A 193
MET A 194
GLU A 195
ASP A 218
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.1A)
 0.70A 3u40A-3of3A:
36.3
3u40F-3of3A:
34.0		 3u40A-3of3A:
46.12
3u40F-3of3A:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.43A 3uawA-3of3A:
38.2		 3uawA-3of3A:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		10 / 11 MET A  78
ARG A 101
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
ASP A 218
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
DIH  A 500 (-3.1A)
None
 0.42A 3uawA-3of3A:
38.2		 3uawA-3of3A:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 10 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.43A 3uayA-3of3A:
37.6		 3uayA-3of3A:
54.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 10 MET A  78
ARG A 101
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
None
 0.34A 3uayA-3of3A:
37.6		 3uayA-3of3A:
54.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 ARG A 101
GLY A 191
VAL A 192
GLU A 193
GLU A 195
VAL A 108
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-2.9A)
None
 1.35A 4d9hA-3of3A:
36.3		 4d9hA-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.33A 4d9hA-3of3A:
36.3		 4d9hA-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 11 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
 0.48A 4d9hA-3of3A:
36.3		 4d9hA-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 SER A 104
GLY A 106
VAL A 192
GLU A 193
SER A 217
ASP A 218
 PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.3A)
DIH  A 500 (-3.1A)
 0.73A 4d9hA-3of3A:
36.3		 4d9hA-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 9 GLY A 106
VAL A 192
MET A 194
SER A 217
ASP A 218
 DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
DIH  A 500 (-3.8A)
DIH  A 500 (-3.3A)
DIH  A 500 (-3.1A)
 0.95A 4da6A-3of3A:
36.0		 4da6A-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		7 / 9 MET A  78
SER A 104
GLY A 106
VAL A 192
MET A 194
GLU A 195
SER A 217
 DIH  A 500 (-3.6A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
 0.68A 4da6A-3of3A:
36.0		 4da6A-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		7 / 10 ARG A 101
GLY A 191
ALA A 170
VAL A 192
GLU A 193
GLU A 195
VAL A 108
 PO4  A 501 (-2.8A)
None
DIH  A 500 ( 4.8A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-2.9A)
None
 1.27A 4da7A-3of3A:
36.5		 4da7A-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		7 / 10 ARG A 101
GLY A 191
ALA A 170
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 ( 4.8A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.26A 4da7A-3of3A:
36.5		 4da7A-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 10 MET A  78
ARG A 101
GLY A 106
ALA A 170
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
DIH  A 500 ( 4.8A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
 0.45A 4da7A-3of3A:
36.5		 4da7A-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 ARG A 101
GLY A 106
VAL A 192
GLU A 193
GLU A 195
VAL A 108
 PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-2.9A)
None
 1.45A 4danA-3of3A:
35.6		 4danA-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 ARG A 101
GLY A 191
VAL A 192
GLU A 193
GLU A 195
VAL A 108
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-2.9A)
None
 1.29A 4danA-3of3A:
35.6		 4danA-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.31A 4danA-3of3A:
35.6		 4danA-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 11 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
 0.54A 4danA-3of3A:
35.6		 4danA-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		7 / 11 SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
SER A 217
ASP A 218
 PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-3.3A)
DIH  A 500 (-3.1A)
 0.73A 4danA-3of3A:
35.6		 4danA-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 12 ARG A 101
GLY A 191
VAL A 192
GLU A 193
GLU A 195
VAL A 108
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-2.9A)
None
 1.29A 4danA-3of3A:
35.6
4danB-3of3A:
36.0		 4danA-3of3A:
50.97
4danB-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 12 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.28A 4danA-3of3A:
35.6
4danB-3of3A:
36.0		 4danA-3of3A:
50.97
4danB-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 12 ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
ASP A 218
 PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
DIH  A 500 (-3.1A)
 0.67A 4danA-3of3A:
35.6
4danB-3of3A:
36.0		 4danA-3of3A:
50.97
4danB-3of3A:
50.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 12 GLU A 171
GLY A 201
ALA A 203
THR A  88
ILE A  91
 None
 1.15A 4hytA-3of3A:
undetectable		 4hytA-3of3A:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_C_OBNC2004_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 12 GLU A 171
GLY A 201
ALA A 203
THR A  88
ILE A  91
 None
 1.15A 4hytC-3of3A:
undetectable		 4hytC-3of3A:
12.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 9 ARG A 101
GLY A 191
ALA A 170
VAL A 192
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 ( 4.8A)
DIH  A 500 (-4.8A)
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.29A 5i3cA-3of3A:
41.3		 5i3cA-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 9 MET A  78
ARG A 101
SER A 104
GLY A 106
ALA A 170
VAL A 192
MET A 194
GLU A 195
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 ( 4.8A)
DIH  A 500 (-4.8A)
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
None
 0.32A 5i3cA-3of3A:
41.3		 5i3cA-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 10 GLY A 191
ALA A 170
VAL A 192
GLU A 193
MET A 194
GLU A 195
 None
DIH  A 500 ( 4.8A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.39A 5i3cB-3of3A:
41.7		 5i3cB-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 10 MET A  78
SER A 104
GLY A 106
ALA A 170
VAL A 192
GLU A 193
MET A 194
GLU A 195
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 ( 4.8A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
None
 0.27A 5i3cB-3of3A:
41.7		 5i3cB-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 11 GLY A 106
ALA A 170
VAL A 192
ASP A 218
ILE A 220
 DIH  A 500 (-4.0A)
DIH  A 500 ( 4.8A)
DIH  A 500 (-4.8A)
DIH  A 500 (-3.1A)
None
 0.94A 5i3cC-3of3A:
41.5		 5i3cC-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 GLY A 191
ALA A 170
VAL A 192
GLU A 193
MET A 194
GLU A 195
 None
DIH  A 500 ( 4.8A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.37A 5i3cC-3of3A:
41.5		 5i3cC-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		10 / 11 MET A  78
SER A 104
GLY A 106
ALA A 170
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 ( 4.8A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
None
 0.40A 5i3cC-3of3A:
41.5		 5i3cC-3of3A:
80.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUE_A_VIVA302_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 12 ILE A 213
ILE A  71
LEU A  31
VAL A 102
ILE A 239
 None
 0.98A 5mueA-3of3A:
undetectable		 5mueA-3of3A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNC_A_QI9A301_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 9 SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
 PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
 0.33A 5zncA-3of3A:
17.6		 5zncA-3of3A:
27.95