SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3of4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 3of4 NITROREDUCTASE
(Idiomarina
loihiensis) 		5 / 12 VAL A 150
PHE A 141
VAL A  76
LEU A  26
THR A  22
 None
None
None
None
SO4  A 305 (-4.3A)
 1.13A 1z9yA-3of4A:
undetectable		 1z9yA-3of4A:
20.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OF4_B_ACTB313_0
(NITROREDUCTASE)		 3of4 NITROREDUCTASE
(Idiomarina
loihiensis) 		3 / 3 ALA A  84
VAL A  85
GLN A 119
 SO4  A 306 (-3.6A)
SO4  A 306 (-3.7A)
SO4  A 306 (-2.9A)
 0.18A 3of4B-3of4A:
33.4		 3of4B-3of4A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MSD_A_BEZA1202_0
(CARBOXYLIC ACID
REDUCTASE)		 3of4 NITROREDUCTASE
(Idiomarina
loihiensis) 		4 / 5 ILE A  21
PHE A  16
SER A 152
ALA A  74
 None
 1.23A 5msdA-3of4A:
undetectable		 5msdA-3of4A:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA810_0
(GEPHYRIN)		 3of4 NITROREDUCTASE
(Idiomarina
loihiensis) 		3 / 3 LEU A 102
LEU A  96
ARG A 100
 None
None
GOL  A 317 (-3.0A)
 0.67A 6fgdA-3of4A:
undetectable		 6fgdA-3of4A:
17.77