SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3of7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_1
(VITAMIN D NUCLEAR
RECEPTOR)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 324
VAL A 296
SER A 342
CYH A 354
VAL A 318
 None
 1.23A 1db1A-3of7A:
undetectable		 1db1A-3of7A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 324
VAL A 296
SER A 342
CYH A 354
VAL A 318
 None
 1.21A 1ie9A-3of7A:
undetectable		 1ie9A-3of7A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RK3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 324
VAL A 296
SER A 342
CYH A 354
VAL A 318
 None
 1.19A 1rk3A-3of7A:
undetectable		 1rk3A-3of7A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_1
(VITAMIN D RECEPTOR)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 324
VAL A 296
SER A 342
CYH A 354
VAL A 318
 None
 1.18A 2hc4A-3of7A:
undetectable		 2hc4A-3of7A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_SAMA201_0
(UPF0066 PROTEIN
AF_0241)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 244
PRO A 321
GLY A 299
LEU A 234
SER A 281
 None
 1.17A 2nv4A-3of7A:
undetectable		 2nv4A-3of7A:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_B_SAMB202_0
(UPF0066 PROTEIN
AF_0241)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 244
PRO A 321
GLY A 299
LEU A 234
SER A 281
 None
 1.29A 2nv4B-3of7A:
undetectable		 2nv4B-3of7A:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1050_2
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 146
PHE A  78
TRP A 106
ARG A 118
 None
 1.44A 2x2iC-3of7A:
0.0		 2x2iC-3of7A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 324
VAL A 296
SER A 342
CYH A 354
VAL A 318
 None
 1.21A 2zlcA-3of7A:
undetectable		 2zlcA-3of7A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_B_SAMB402_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 PHE A  78
LEU A  61
PHE A  89
PRO A 150
ILE A  87
 None
 1.17A 2zznB-3of7A:
undetectable		 2zznB-3of7A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M7R_A_VDXA425_1
(VITAMIN D3 RECEPTOR)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 324
VAL A 296
SER A 342
CYH A 354
VAL A 318
 None
 1.15A 3m7rA-3of7A:
undetectable		 3m7rA-3of7A:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_A_BEZA999_0
(CHOLINESTERASE)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 7 GLY A 355
SER A 342
LEU A 324
PHE A 287
HIS A 285
 None
 1.08A 3o9mA-3of7A:
undetectable		 3o9mA-3of7A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.91A 3uboB-3of7A:
undetectable		 3uboB-3of7A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UPR_A_1KXA277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 10 ILE A 223
VAL A 186
TYR A 187
ILE A 233
TRP A 245
 None
 1.32A 3uprA-3of7A:
undetectable		 3uprA-3of7A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UPR_C_1KXC277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 10 ILE A 223
VAL A 186
TYR A 187
ILE A 233
TRP A 245
 None
 1.34A 3uprC-3of7A:
undetectable		 3uprC-3of7A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 324
VAL A 296
SER A 342
CYH A 354
VAL A 318
 None
 1.21A 3vt3A-3of7A:
undetectable		 3vt3A-3of7A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVA_B_T3B1314_1
(THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 426
GLY A 421
PHE A 431
ARG A  72
PRO A  73
 None
 1.27A 4bvaB-3of7A:
undetectable		 4bvaB-3of7A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.95A 4e3aA-3of7A:
undetectable		 4e3aA-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_2
(NEURAMINIDASE)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 428
ARG A  72
TRP A  51
ASN A 450
 None
 1.35A 4i00A-3of7A:
7.2		 4i00A-3of7A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.94A 4jksA-3of7A:
undetectable		 4jksA-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.94A 4jksB-3of7A:
undetectable		 4jksB-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.95A 4jkuA-3of7A:
undetectable		 4jkuA-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.96A 4jkuB-3of7A:
undetectable		 4jkuB-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.94A 4k8cA-3of7A:
undetectable		 4k8cA-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.95A 4k8cB-3of7A:
undetectable		 4k8cB-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.94A 4k8kA-3of7A:
undetectable		 4k8kA-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.94A 4k8kB-3of7A:
undetectable		 4k8kB-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.95A 4k8pA-3of7A:
undetectable		 4k8pA-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.96A 4k8pB-3of7A:
undetectable		 4k8pB-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.94A 4k8tA-3of7A:
undetectable		 4k8tA-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.93A 4k8tB-3of7A:
undetectable		 4k8tB-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.95A 4k93A-3of7A:
undetectable		 4k93A-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.95A 4k93B-3of7A:
undetectable		 4k93B-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.94A 4k9cA-3of7A:
undetectable		 4k9cA-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.96A 4k9cB-3of7A:
undetectable		 4k9cB-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.96A 4k9iA-3of7A:
undetectable		 4k9iA-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.95A 4k9iB-3of7A:
undetectable		 4k9iB-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.94A 4kadA-3of7A:
undetectable		 4kadA-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.96A 4kadB-3of7A:
undetectable		 4kadB-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.94A 4kahA-3of7A:
undetectable		 4kahA-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.94A 4kahB-3of7A:
undetectable		 4kahB-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.93A 4kalA-3of7A:
undetectable		 4kalA-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.94A 4kalB-3of7A:
undetectable		 4kalB-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.95A 4kanA-3of7A:
undetectable		 4kanA-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.95A 4kanB-3of7A:
undetectable		 4kanB-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.95A 4kbeA-3of7A:
undetectable		 4kbeA-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.93A 4kbeB-3of7A:
undetectable		 4kbeB-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.95A 4lbgA-3of7A:
undetectable		 4lbgA-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.95A 4lbgB-3of7A:
undetectable		 4lbgB-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.95A 4lbxA-3of7A:
undetectable		 4lbxA-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.94A 4lbxB-3of7A:
undetectable		 4lbxB-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.95A 4lc4A-3of7A:
undetectable		 4lc4A-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.95A 4lc4B-3of7A:
undetectable		 4lc4B-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.93A 4lcaA-3of7A:
undetectable		 4lcaA-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 450
ILE A 452
GLY A 464
GLY A 465
SER A  42
 None
 0.94A 4lcaB-3of7A:
undetectable		 4lcaB-3of7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_H_377H401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		4 / 6 GLU A 163
GLU A 185
TYR A 187
PHE A 181
 None
 1.48A 4twdG-3of7A:
undetectable
4twdH-3of7A:
undetectable		 4twdG-3of7A:
21.12
4twdH-3of7A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_H_377H402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		4 / 5 GLU A 163
GLU A 185
TYR A 187
PHE A 181
 None
 1.46A 4twdH-3of7A:
0.0
4twdI-3of7A:
0.0		 4twdH-3of7A:
21.12
4twdI-3of7A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_B_DIFB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		4 / 8 SER A 406
LEU A 351
LEU A 345
ILE A 335
 None
 0.99A 4xtaB-3of7A:
undetectable		 4xtaB-3of7A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 11 GLY A 338
SER A 406
LEU A 351
LEU A 345
ILE A 335
 None
 1.06A 4xumB-3of7A:
undetectable		 4xumB-3of7A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y1D_D_DVAD5_0
(CYCLIC HEXAPEPTIDE
CYC[NDPOPPKID]
INTEGRASE)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		3 / 3 GLU A 102
LYS A  85
ASN A 104
 None
 0.99A 4y1dA-3of7A:
undetectable
4y1dD-3of7A:
undetectable		 4y1dA-3of7A:
16.45
4y1dD-3of7A:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		4 / 7 VAL A 462
TRP A 108
HIS A  95
GLU A  58
 None
 1.34A 5ad9A-3of7A:
undetectable
5ad9B-3of7A:
undetectable		 5ad9A-3of7A:
21.91
5ad9B-3of7A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_B_HFGB703_0
(AMINOACYL-TRNA
SYNTHETASE)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 273
PHE A 271
PRO A 321
SER A 342
GLY A 304
 None
 1.15A 5f9zB-3of7A:
undetectable		 5f9zB-3of7A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 11 GLY A 458
GLU A  58
GLY A  93
VAL A 462
ALA A 425
 None
 0.97A 5o96G-3of7A:
undetectable		 5o96G-3of7A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U98_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 10 ILE A 223
VAL A 186
TYR A 187
ILE A 233
TRP A 245
 None
 1.33A 5u98A-3of7A:
undetectable		 5u98A-3of7A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U98_D_1KXD301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 10 ILE A 223
VAL A 186
TYR A 187
ILE A 233
TRP A 245
 None
 1.35A 5u98D-3of7A:
undetectable		 5u98D-3of7A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		5 / 12 SER A 463
VAL A  70
GLY A  52
SER A 461
PHE A  89
 None
 1.10A 6a94A-3of7A:
undetectable		 6a94A-3of7A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 341
VAL A 399
LEU A 343
ALA A 401
 None
 1.39A 6d8pB-3of7A:
undetectable		 6d8pB-3of7A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_D_READ601_1
(RETINOIC ACID
RECEPTOR)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 143
LEU A  97
GLY A  92
GLY A  54
 None
 0.53A 6eu9D-3of7A:
undetectable		 6eu9D-3of7A:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3of7 REGULATOR OF
CHROMOSOME
CONDENSATION
(Saccharomyces
cerevisiae) 		4 / 6 LEU A 263
VAL A 215
PHE A 192
PHE A 235
 None
 0.98A 6h7lB-3of7A:
undetectable		 6h7lB-3of7A:
10.02