SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ofj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3ofj NODULATION PROTEIN S
(Bradyrhizobium
sp.
WM9) 		5 / 12 ILE A  72
GLY A  52
MET A 133
LEU A 110
LEU A  35
 None
 1.23A 1fm6X-3ofjA:
undetectable		 1fm6X-3ofjA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3ofj NODULATION PROTEIN S
(Bradyrhizobium
sp.
WM9) 		5 / 12 ARG A  31
GLY A  52
VAL A  74
ALA A 114
ILE A  99
 None
 0.99A 3ku1H-3ofjA:
12.9		 3ku1H-3ofjA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 3ofj NODULATION PROTEIN S
(Bradyrhizobium
sp.
WM9) 		5 / 12 LEU A 192
THR A  59
ILE A  92
LEU A 110
VAL A 144
 None
 1.27A 3sp9A-3ofjA:
undetectable		 3sp9A-3ofjA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ofj NODULATION PROTEIN S
(Bradyrhizobium
sp.
WM9) 		4 / 7 LEU A  36
GLN A  34
PHE A  58
LEU A  62
 None
 0.89A 5b1aC-3ofjA:
undetectable
5b1aJ-3ofjA:
undetectable		 5b1aC-3ofjA:
21.83
5b1aJ-3ofjA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ofj NODULATION PROTEIN S
(Bradyrhizobium
sp.
WM9) 		4 / 7 LEU A  36
GLN A  34
PHE A  58
LEU A  62
 None
 0.87A 5b1aP-3ofjA:
undetectable
5b1aW-3ofjA:
undetectable		 5b1aP-3ofjA:
21.83
5b1aW-3ofjA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ofj NODULATION PROTEIN S
(Bradyrhizobium
sp.
WM9) 		4 / 7 LEU A  36
GLN A  34
PHE A  58
LEU A  62
 None
 0.84A 5b3sC-3ofjA:
undetectable
5b3sJ-3ofjA:
undetectable		 5b3sC-3ofjA:
21.83
5b3sJ-3ofjA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ofj NODULATION PROTEIN S
(Bradyrhizobium
sp.
WM9) 		4 / 7 LEU A  36
GLN A  34
PHE A  58
LEU A  62
 None
 0.86A 5b3sP-3ofjA:
undetectable		 5b3sP-3ofjA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ofj NODULATION PROTEIN S
(Bradyrhizobium
sp.
WM9) 		4 / 7 LEU A  36
GLN A  34
PHE A  58
LEU A  62
 None
 0.85A 5iy5C-3ofjA:
undetectable
5iy5J-3ofjA:
undetectable		 5iy5C-3ofjA:
21.30
5iy5J-3ofjA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ofj NODULATION PROTEIN S
(Bradyrhizobium
sp.
WM9) 		4 / 7 LEU A  36
GLN A  34
PHE A  58
LEU A  62
 None
 0.88A 5z84C-3ofjA:
undetectable
5z84J-3ofjA:
undetectable		 5z84C-3ofjA:
21.83
5z84J-3ofjA:
16.48