SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3og5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_B_BEZB1503_0
(RAS-RELATED PROTEIN
RAB-9A)		 3og5 OUTER MEMBRANE
PROTEIN ASSEMBLY
COMPLEX, YAET
PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 412
LEU A 377
ARG A 346
PHE A 347
 None
 1.08A 1s8fB-3og5A:
undetectable		 1s8fB-3og5A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 3og5 OUTER MEMBRANE
PROTEIN ASSEMBLY
COMPLEX, YAET
PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 389
ASN A 390
LEU A 392
GLY A 393
THR A 397
 None
 1.27A 2q7lA-3og5A:
undetectable		 2q7lA-3og5A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_A_RKEA401_1
(PROTON-GATED ION
CHANNEL)		 3og5 OUTER MEMBRANE
PROTEIN ASSEMBLY
COMPLEX, YAET
PROTEIN
(Escherichia
coli) 		4 / 8 ASN A 357
ASP A 358
VAL A 364
PHE A 395
 None
 0.98A 4f8hA-3og5A:
undetectable
4f8hB-3og5A:
undetectable		 4f8hA-3og5A:
18.32
4f8hB-3og5A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_B_RKEB401_1
(PROTON-GATED ION
CHANNEL)		 3og5 OUTER MEMBRANE
PROTEIN ASSEMBLY
COMPLEX, YAET
PROTEIN
(Escherichia
coli) 		4 / 8 ASN A 357
ASP A 358
VAL A 364
PHE A 395
 None
 0.99A 4f8hB-3og5A:
undetectable
4f8hC-3og5A:
undetectable		 4f8hB-3og5A:
18.32
4f8hC-3og5A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_C_RKEC401_1
(PROTON-GATED ION
CHANNEL)		 3og5 OUTER MEMBRANE
PROTEIN ASSEMBLY
COMPLEX, YAET
PROTEIN
(Escherichia
coli) 		4 / 8 ASN A 357
ASP A 358
VAL A 364
PHE A 395
 None
 0.99A 4f8hC-3og5A:
undetectable
4f8hD-3og5A:
undetectable		 4f8hC-3og5A:
18.32
4f8hD-3og5A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_D_RKED401_1
(PROTON-GATED ION
CHANNEL)		 3og5 OUTER MEMBRANE
PROTEIN ASSEMBLY
COMPLEX, YAET
PROTEIN
(Escherichia
coli) 		4 / 8 ASN A 357
ASP A 358
VAL A 364
PHE A 395
 None
 0.97A 4f8hD-3og5A:
undetectable
4f8hE-3og5A:
undetectable		 4f8hD-3og5A:
18.32
4f8hE-3og5A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_E_RKEE401_1
(PROTON-GATED ION
CHANNEL)		 3og5 OUTER MEMBRANE
PROTEIN ASSEMBLY
COMPLEX, YAET
PROTEIN
(Escherichia
coli) 		4 / 8 VAL A 364
PHE A 395
ASN A 357
ASP A 358
 None
 0.97A 4f8hA-3og5A:
undetectable
4f8hE-3og5A:
undetectable		 4f8hA-3og5A:
18.32
4f8hE-3og5A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3og5 OUTER MEMBRANE
PROTEIN ASSEMBLY
COMPLEX, YAET
PROTEIN
(Escherichia
coli) 		3 / 3 VAL A 349
VAL A 412
GLN A 403
 None
 0.63A 5qh5A-3og5A:
undetectable		 5qh5A-3og5A:
20.19