SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3og9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 3og9 PROTEIN YAHD A
COPPER INDUCIBLE
HYDROLASE
(Lactococcus
lactis) 		4 / 6 ALA A 110
SER A 185
TRP A 201
LEU A 114
 None
 1.12A 1gahA-3og9A:
undetectable		 1gahA-3og9A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_2
(HMG-COA REDUCTASE)		 3og9 PROTEIN YAHD A
COPPER INDUCIBLE
HYDROLASE
(Lactococcus
lactis) 		4 / 8 ASN A 108
LEU A  19
ALA A 103
LEU A  17
 MLT  A 500 (-3.9A)
None
None
None
 0.94A 1hwiD-3og9A:
undetectable		 1hwiD-3og9A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3og9 PROTEIN YAHD A
COPPER INDUCIBLE
HYDROLASE
(Lactococcus
lactis) 		4 / 5 GLY A  65
PRO A 161
VAL A 160
ILE A 159
 None
None
None
MLT  A 500 ( 4.6A)
 0.98A 2aoiA-3og9A:
undetectable		 2aoiA-3og9A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZQ_A_PCFA954_0
(CATECHOL
1,2-DIOXYGENASE)		 3og9 PROTEIN YAHD A
COPPER INDUCIBLE
HYDROLASE
(Lactococcus
lactis) 		5 / 9 LEU A  29
GLU A 194
ALA A 198
LEU A 202
LEU A 151
 None
 1.37A 2azqA-3og9A:
undetectable		 2azqA-3og9A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_F_CSCF1383_2
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 3og9 PROTEIN YAHD A
COPPER INDUCIBLE
HYDROLASE
(Lactococcus
lactis) 		3 / 3 LEU A  17
MET A 101
MET A  35
 None
 1.02A 2vavF-3og9A:
14.3		 2vavF-3og9A:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 3og9 PROTEIN YAHD A
COPPER INDUCIBLE
HYDROLASE
(Lactococcus
lactis) 		4 / 4 LEU A 172
ILE A 181
GLY A 170
PHE A 165
 None
 1.07A 4dc3A-3og9A:
4.5		 4dc3A-3og9A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_C_IPHC101_0
(INSULIN)		 3og9 PROTEIN YAHD A
COPPER INDUCIBLE
HYDROLASE
(Lactococcus
lactis) 		5 / 11 LEU A 114
HIS A 131
ALA A 129
LEU A 151
VAL A 160
 None
 1.07A 4p65C-3og9A:
undetectable
4p65D-3og9A:
undetectable
4p65J-3og9A:
undetectable
4p65L-3og9A:
undetectable		 4p65C-3og9A:
5.77
4p65D-3og9A:
9.60
4p65J-3og9A:
9.60
4p65L-3og9A:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_I_IPHI101_0
(INSULIN)		 3og9 PROTEIN YAHD A
COPPER INDUCIBLE
HYDROLASE
(Lactococcus
lactis) 		5 / 12 VAL A 160
LEU A 151
LEU A 114
HIS A 131
ALA A 129
 None
 0.98A 4p65B-3og9A:
undetectable
4p65D-3og9A:
undetectable
4p65I-3og9A:
undetectable
4p65J-3og9A:
undetectable		 4p65B-3og9A:
9.60
4p65D-3og9A:
9.60
4p65I-3og9A:
5.77
4p65J-3og9A:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGZ_A_SPRA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3og9 PROTEIN YAHD A
COPPER INDUCIBLE
HYDROLASE
(Lactococcus
lactis) 		5 / 9 LEU A 190
HIS A 131
ILE A  36
GLU A  34
GLU A 193
 None
 1.41A 5igzA-3og9A:
undetectable		 5igzA-3og9A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_D_SAMD501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3og9 PROTEIN YAHD A
COPPER INDUCIBLE
HYDROLASE
(Lactococcus
lactis) 		5 / 10 LEU A  18
HIS A  20
ILE A 104
GLY A 105
GLY A 109
 None
 0.87A 5o96C-3og9A:
undetectable
5o96D-3og9A:
undetectable		 5o96C-3og9A:
24.22
5o96D-3og9A:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 3og9 PROTEIN YAHD A
COPPER INDUCIBLE
HYDROLASE
(Lactococcus
lactis) 		5 / 12 LEU A  18
ILE A  45
ILE A 104
GLY A 105
GLY A 109
 None
 0.95A 5twjA-3og9A:
undetectable		 5twjA-3og9A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_B_GLYB709_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3og9 PROTEIN YAHD A
COPPER INDUCIBLE
HYDROLASE
(Lactococcus
lactis) 		4 / 5 GLY A  24
ASN A  55
ASP A  25
ARG A  46
 None
 1.36A 6dwdB-3og9A:
undetectable
6dwdD-3og9A:
undetectable		 6dwdB-3og9A:
17.46
6dwdD-3og9A:
17.46