SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ogr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3002_1
(SERUM ALBUMIN)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 8 LEU A 860
LYS A 950
LEU A 807
SER A 804
 None
 1.01A 1hk3A-3ogrA:
undetectable		 1hk3A-3ogrA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K4T_D_TTCD990_1
(DNA TOPOISOMERASE I)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 5 GLU A 960
ARG A 372
ASP A  80
THR A1003
 None
 1.47A 1k4tA-3ogrA:
undetectable		 1k4tA-3ogrA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		3 / 3 PHE A 148
TRP A  99
GLU A 103
 None
 1.04A 1mogA-3ogrA:
undetectable		 1mogA-3ogrA:
5.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA444_1
(ALPHA AMYLASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 7 TYR A 948
ASN A 974
TYR A 970
GLY A 972
 None
 1.23A 1mxgA-3ogrA:
10.5		 1mxgA-3ogrA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		3 / 3 GLU A 322
ASN A 320
TRP A 272
 MAN  A1029 (-3.5A)
MAN  A1031 (-3.9A)
None
 1.27A 1r15C-3ogrA:
undetectable		 1r15C-3ogrA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		3 / 3 GLU A 322
ASN A 320
TRP A 272
 MAN  A1029 (-3.5A)
MAN  A1031 (-3.9A)
None
 1.26A 1r15D-3ogrA:
undetectable		 1r15D-3ogrA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		3 / 3 GLU A 322
ASN A 320
TRP A 272
 MAN  A1029 (-3.5A)
MAN  A1031 (-3.9A)
None
 1.26A 1r15E-3ogrA:
1.8		 1r15E-3ogrA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		3 / 3 GLU A 322
ASN A 320
TRP A 272
 MAN  A1029 (-3.5A)
MAN  A1031 (-3.9A)
None
 1.22A 1r15F-3ogrA:
undetectable		 1r15F-3ogrA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_0
(SUN PROTEIN)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		5 / 12 ALA A 303
GLY A 302
GLY A 301
ASP A 265
GLY A 357
 None
None
None
MAN  A1039 ( 2.9A)
None
 1.03A 1sqfA-3ogrA:
undetectable		 1sqfA-3ogrA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 7 PHE A 327
PHE A 299
LEU A 296
PHE A 294
 None
 0.96A 2eikC-3ogrA:
undetectable
2eikJ-3ogrA:
undetectable		 2eikC-3ogrA:
14.48
2eikJ-3ogrA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 7 PHE A 327
PHE A 299
LEU A 296
PHE A 294
 None
 0.96A 2eimP-3ogrA:
undetectable
2eimW-3ogrA:
undetectable		 2eimP-3ogrA:
14.48
2eimW-3ogrA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 8 HIS A 285
ALA A 334
LEU A 296
HIS A 257
 None
 0.92A 2it4A-3ogrA:
undetectable		 2it4A-3ogrA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 6 THR A 812
ARG A 160
ASP A 236
ASP A 284
 None
 1.29A 2okcB-3ogrA:
undetectable		 2okcB-3ogrA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 7 LEU A 382
PHE A  90
ILE A 341
PHE A 339
 None
 0.94A 2opxA-3ogrA:
undetectable		 2opxA-3ogrA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA701_0
(FERROCHELATASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 8 LEU A  53
PRO A 245
SER A 289
GLY A  40
 None
 0.91A 2qd5A-3ogrA:
undetectable		 2qd5A-3ogrA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1103_0
(FERROCHELATASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 8 LEU A  53
PRO A 245
SER A 289
GLY A  40
 None
 0.94A 2qd5B-3ogrA:
undetectable		 2qd5B-3ogrA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEO_A_LNRA200_1
(D7R4 PROTEIN)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		5 / 12 GLU A 809
TYR A 342
ILE A 139
VAL A 143
TYR A  96
 GAL  A1024 ( 4.8A)
GAL  A1024 (-4.4A)
None
None
GAL  A1024 (-4.6A)
 1.40A 2qeoA-3ogrA:
undetectable		 2qeoA-3ogrA:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 5 PHE A 327
PHE A 299
LEU A 296
PHE A 294
 None
 0.89A 2y69C-3ogrA:
undetectable
2y69J-3ogrA:
undetectable		 2y69C-3ogrA:
14.48
2y69J-3ogrA:
5.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 5 PHE A 327
PHE A 299
LEU A 296
PHE A 294
 None
 0.93A 2y69P-3ogrA:
undetectable
2y69W-3ogrA:
undetectable		 2y69P-3ogrA:
14.48
2y69W-3ogrA:
5.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 6 PHE A 327
PHE A 299
LEU A 296
PHE A 294
 None
 1.01A 3abkP-3ogrA:
undetectable
3abkW-3ogrA:
undetectable		 3abkP-3ogrA:
14.48
3abkW-3ogrA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 6 PHE A 327
PHE A 299
LEU A 296
PHE A 294
 None
 1.07A 3ablP-3ogrA:
undetectable
3ablW-3ogrA:
undetectable		 3ablP-3ogrA:
14.48
3ablW-3ogrA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 5 PHE A 327
PHE A 299
LEU A 296
PHE A 294
 None
 0.91A 3abmC-3ogrA:
undetectable
3abmJ-3ogrA:
undetectable		 3abmC-3ogrA:
14.48
3abmJ-3ogrA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 5 PHE A 327
PHE A 299
LEU A 296
PHE A 294
 None
 0.90A 3abmP-3ogrA:
undetectable
3abmW-3ogrA:
undetectable		 3abmP-3ogrA:
14.48
3abmW-3ogrA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 5 PHE A 327
PHE A 299
LEU A 296
PHE A 294
 None
 0.91A 3ag3C-3ogrA:
undetectable
3ag3J-3ogrA:
undetectable		 3ag3C-3ogrA:
14.48
3ag3J-3ogrA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 8 PHE A 327
PHE A 299
LEU A 296
PHE A 294
 None
 0.94A 3ag4C-3ogrA:
undetectable
3ag4J-3ogrA:
undetectable		 3ag4C-3ogrA:
14.48
3ag4J-3ogrA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 7 PHE A 327
PHE A 299
LEU A 296
PHE A 294
 None
 0.92A 3ag4P-3ogrA:
undetectable
3ag4W-3ogrA:
undetectable		 3ag4P-3ogrA:
14.48
3ag4W-3ogrA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 7 PHE A 327
PHE A 299
LEU A 296
PHE A 294
 None
 0.96A 3asnP-3ogrA:
undetectable
3asnW-3ogrA:
undetectable		 3asnP-3ogrA:
14.48
3asnW-3ogrA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_2
(PHOSPHOLIPASE A2)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 5 ILE A 114
PRO A  73
PHE A  70
PRO A  69
 None
 1.30A 3bjwC-3ogrA:
undetectable		 3bjwC-3ogrA:
7.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 6 THR A 475
ILE A 456
LEU A 454
THR A 449
 None
 0.81A 3deuB-3ogrA:
undetectable		 3deuB-3ogrA:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 6 GLY A 731
GLU A 868
GLY A 864
ASN A 352
 None
 1.09A 3e9rA-3ogrA:
undetectable		 3e9rA-3ogrA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_C_ACTC700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 6 GLY A 731
GLU A 868
GLY A 864
ASN A 352
 None
 1.03A 3e9rC-3ogrA:
undetectable		 3e9rC-3ogrA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 7 LEU A  53
PRO A 245
SER A 289
GLY A  40
 None
 1.05A 3hcnA-3ogrA:
undetectable		 3hcnA-3ogrA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 7 LEU A  53
PRO A 245
SER A 289
GLY A  40
 None
 0.97A 3hcrB-3ogrA:
undetectable		 3hcrB-3ogrA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		5 / 12 LEU A 102
ASP A  98
VAL A  97
ILE A 139
GLY A 147
 None
 1.08A 3hgiA-3ogrA:
undetectable		 3hgiA-3ogrA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 4 PRO A 278
THR A 280
GLY A 240
THR A 242
 None
 1.16A 3ib1A-3ogrA:
undetectable		 3ib1A-3ogrA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		3 / 3 ASN A 234
ASN A 199
GLU A 298
 None
GAL  A1024 (-3.1A)
GAL  A1024 (-2.7A)
 0.89A 3kpdC-3ogrA:
undetectable		 3kpdC-3ogrA:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 6 SER A 487
ILE A 491
ASP A 571
THR A 464
 None
 0.88A 3q70A-3ogrA:
undetectable		 3q70A-3ogrA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_0
(2'-O-METHYL
TRANSFERASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		5 / 12 GLY A 357
SER A 144
GLY A 755
ASN A 349
PHE A 304
 None
None
None
None
GAL  A1024 ( 4.8A)
 1.39A 3r24A-3ogrA:
undetectable		 3r24A-3ogrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 6 GLN A 947
TYR A 942
PHE A 867
LEU A 865
 None
 1.43A 3tgvB-3ogrA:
undetectable		 3tgvB-3ogrA:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 6 GLN A 947
TYR A 942
PHE A 867
LEU A 865
 None
 1.38A 3tgvD-3ogrA:
undetectable		 3tgvD-3ogrA:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEM_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		5 / 12 ALA A 624
PHE A 626
ILE A 368
ASP A  80
ASP A 625
 None
 1.31A 3wemA-3ogrA:
7.7		 3wemA-3ogrA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		5 / 12 ALA A 624
PHE A 626
ILE A 368
ASP A  80
ASP A 625
 None
 1.30A 3weoA-3ogrA:
7.6		 3weoA-3ogrA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_ACTB1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 7 PRO A1000
ILE A 922
VAL A 674
SER A 997
 None
 0.90A 4a3uB-3ogrA:
10.6		 4a3uB-3ogrA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		5 / 12 TYR A 948
GLY A 945
GLY A1013
LEU A 940
GLY A 863
 None
 1.07A 4blvA-3ogrA:
undetectable		 4blvA-3ogrA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 7 ASN A 331
ALA A 333
THR A 417
LEU A 277
 None
 0.92A 4ejgA-3ogrA:
undetectable		 4ejgA-3ogrA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 8 ASN A 331
ALA A 333
THR A 417
LEU A 277
 None
 0.94A 4ejgB-3ogrA:
undetectable		 4ejgB-3ogrA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA304_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		3 / 3 ARG A  71
HIS A  68
TYR A 362
 None
 1.28A 4fu8A-3ogrA:
undetectable		 4fu8A-3ogrA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD305_0
(GLUTATHIONE
TRANSFERASE GTE1)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 4 ILE A 976
LEU A 911
LYS A 910
ASN A 944
 None
 1.14A 4g19D-3ogrA:
undetectable		 4g19D-3ogrA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVR_A_SALA203_1
(3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 7 GLU A  66
HIS A  68
PRO A  69
VAL A  93
 None
 1.13A 4hvrA-3ogrA:
undetectable		 4hvrA-3ogrA:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 7 ILE A 539
THR A 541
VAL A 559
PHE A 521
 None
 0.89A 4iarA-3ogrA:
undetectable		 4iarA-3ogrA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 8 LEU A  53
PRO A 245
SER A 289
GLY A  40
 None
 1.02A 4klrB-3ogrA:
undetectable		 4klrB-3ogrA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		5 / 11 GLY A 845
ARG A 869
LEU A 865
GLY A 863
ALA A 935
 None
 1.20A 4l6v1-3ogrA:
undetectable
4l6v6-3ogrA:
undetectable		 4l6v1-3ogrA:
22.24
4l6v6-3ogrA:
8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_B_9TPB601_1
(SERUM ALBUMIN)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		5 / 12 LEU A 596
PRO A 599
ILE A 129
LEU A  88
GLY A  65
 None
 1.21A 4l9qB-3ogrA:
undetectable		 4l9qB-3ogrA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 7 ASN A 320
GLU A 377
GLU A 381
GLU A 322
 MAN  A1031 (-3.9A)
MAN  A1028 (-2.7A)
None
MAN  A1029 (-3.5A)
 1.26A 4mi4A-3ogrA:
undetectable
4mi4C-3ogrA:
undetectable		 4mi4A-3ogrA:
11.01
4mi4C-3ogrA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 7 ASN A 320
GLU A 377
GLU A 381
GLU A 322
 MAN  A1031 (-3.9A)
MAN  A1028 (-2.7A)
None
MAN  A1029 (-3.5A)
 1.30A 4mj8C-3ogrA:
undetectable		 4mj8C-3ogrA:
10.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJK_A_SAMA302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		5 / 12 THR A 813
GLU A 200
ASN A 199
VAL A 219
ASP A 162
 None
GAL  A1024 (-2.5A)
GAL  A1024 (-3.1A)
None
None
 1.50A 4njkA-3ogrA:
3.0		 4njkA-3ogrA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJK_B_SAMB302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		5 / 12 THR A 813
GLU A 200
ASN A 199
VAL A 219
ASP A 162
 None
GAL  A1024 (-2.5A)
GAL  A1024 (-3.1A)
None
None
 1.47A 4njkB-3ogrA:
2.5		 4njkB-3ogrA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R82_A_ACTA205_0
(OXIDOREDUCTASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 5 SER A 724
GLY A 723
ARG A 154
GLU A 850
 None
 0.96A 4r82A-3ogrA:
undetectable
4r82B-3ogrA:
undetectable		 4r82A-3ogrA:
11.38
4r82B-3ogrA:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 7 ASN A 320
GLU A 377
GLU A 381
GLU A 322
 MAN  A1031 (-3.9A)
MAN  A1028 (-2.7A)
None
MAN  A1029 (-3.5A)
 1.18A 4r87I-3ogrA:
undetectable		 4r87I-3ogrA:
10.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		3 / 3 GLU A 298
TYR A 362
GLU A 142
 GAL  A1024 (-2.7A)
None
GAL  A1024 (-2.8A)
 0.78A 4ryaA-3ogrA:
undetectable		 4ryaA-3ogrA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_ADNA2414_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 6 GLU A 122
PHE A 121
PHE A 120
TYR A  78
 None
 1.40A 4uciA-3ogrA:
undetectable		 4uciA-3ogrA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_ADNB2415_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 7 GLU A 122
PHE A 121
PHE A 120
TYR A  78
 None
 1.40A 4uciB-3ogrA:
undetectable		 4uciB-3ogrA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIN_H_QI9H1226_0
(FAB 314.3)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		5 / 12 TRP A  99
THR A 170
GLY A 145
LEU A 152
PRO A 149
 None
 1.46A 4uinH-3ogrA:
undetectable
4uinL-3ogrA:
undetectable		 4uinH-3ogrA:
12.70
4uinL-3ogrA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		5 / 11 GLN A 222
ALA A 223
HIS A 168
VAL A 174
THR A 170
 None
 1.03A 4uuuA-3ogrA:
undetectable
4uuuB-3ogrA:
undetectable		 4uuuA-3ogrA:
10.17
4uuuB-3ogrA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_A_EF2A151_1
(CEREBLON ISOFORM 4)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 7 PRO A  69
PHE A  70
TRP A 350
TYR A 948
 None
 1.40A 4v2yA-3ogrA:
undetectable		 4v2yA-3ogrA:
8.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_A_Y70A151_1
(CEREBLON ISOFORM 4)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 7 PRO A  69
PHE A  70
TRP A 350
TYR A 948
 None
 1.42A 4v2zA-3ogrA:
undetectable		 4v2zA-3ogrA:
8.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_A_LVYA151_1
(CEREBLON ISOFORM 4)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 7 PRO A  69
PHE A  70
TRP A 350
TYR A 948
 None
 1.40A 4v30A-3ogrA:
undetectable		 4v30A-3ogrA:
8.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_A_RTZA602_1
(CYTOCHROME P450 2D6)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		5 / 12 GLY A 563
LEU A 562
GLN A 561
VAL A 517
VAL A 537
 None
 1.21A 4wnwA-3ogrA:
undetectable		 4wnwA-3ogrA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		5 / 12 PHE A 926
LEU A 968
LEU A 913
LEU A 915
TYR A 970
 None
 1.17A 4xumA-3ogrA:
undetectable		 4xumA-3ogrA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_B_EF2B151_1
(CEREBLON ISOFORM 4)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 7 PRO A  69
PHE A  70
TRP A 350
TYR A 948
 None
 1.41A 5amkB-3ogrA:
undetectable		 5amkB-3ogrA:
8.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 6 PHE A 327
PHE A 299
LEU A 296
PHE A 294
 None
 1.15A 5b1bC-3ogrA:
undetectable
5b1bJ-3ogrA:
undetectable		 5b1bC-3ogrA:
14.48
5b1bJ-3ogrA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSM_A_GCSA801_1
(EXO-BETA-D-GLUCOSAMI
NIDASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		5 / 12 TYR A  96
GLU A 142
GLU A 200
GLU A 298
TYR A 342
 GAL  A1024 (-4.6A)
GAL  A1024 (-2.8A)
GAL  A1024 (-2.5A)
GAL  A1024 (-2.7A)
GAL  A1024 (-4.4A)
 0.84A 5gsmA-3ogrA:
14.4		 5gsmA-3ogrA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSM_B_GCSB801_1
(EXO-BETA-D-GLUCOSAMI
NIDASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		5 / 12 TYR A  96
GLU A 142
GLU A 200
GLU A 298
TYR A 342
 GAL  A1024 (-4.6A)
GAL  A1024 (-2.8A)
GAL  A1024 (-2.5A)
GAL  A1024 (-2.7A)
GAL  A1024 (-4.4A)
 0.84A 5gsmB-3ogrA:
14.8		 5gsmB-3ogrA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI6_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		5 / 12 ILE A 186
SER A  64
ILE A  62
LEU A  53
TYR A 592
 None
 1.18A 5hi6B-3ogrA:
undetectable		 5hi6B-3ogrA:
10.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I9Y_A_1N1A1001_2
(EPHRIN TYPE-A
RECEPTOR 2)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		3 / 3 ILE A 472
ILE A 416
MET A 332
 None
 0.62A 5i9yA-3ogrA:
undetectable		 5i9yA-3ogrA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGP_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		5 / 12 ILE A 641
PRO A 638
VAL A 613
ALA A 591
GLY A 587
 None
 0.96A 5igpA-3ogrA:
undetectable		 5igpA-3ogrA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		5 / 12 ILE A 641
PRO A 638
VAL A 613
ALA A 591
GLY A 587
 None
 0.95A 5igtA-3ogrA:
1.0		 5igtA-3ogrA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		3 / 3 THR A 488
SER A 487
TYR A 486
 None
 0.83A 5jsdA-3ogrA:
undetectable		 5jsdA-3ogrA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		3 / 3 THR A 488
SER A 487
TYR A 486
 None
 0.84A 5jsdB-3ogrA:
undetectable		 5jsdB-3ogrA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		3 / 3 THR A 488
SER A 487
TYR A 486
 None
 0.83A 5jsdC-3ogrA:
undetectable		 5jsdC-3ogrA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		3 / 3 THR A 488
SER A 487
TYR A 486
 None
 0.82A 5jseA-3ogrA:
undetectable		 5jseA-3ogrA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		3 / 3 THR A 488
SER A 487
TYR A 486
 None
 0.81A 5jseB-3ogrA:
undetectable		 5jseB-3ogrA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		3 / 3 THR A 488
SER A 487
TYR A 486
 None
 0.81A 5jseC-3ogrA:
undetectable		 5jseC-3ogrA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 5 ALA A 624
VAL A 622
PHE A 626
ILE A 634
 None
 0.90A 5of1A-3ogrA:
undetectable		 5of1A-3ogrA:
7.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 5 ALA A 624
VAL A 622
PHE A 626
ILE A 634
 None
 0.89A 5of1B-3ogrA:
4.1		 5of1B-3ogrA:
7.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_A_EF2A202_0
(CEREBLON ISOFORM 4)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 7 PRO A  69
PHE A  70
TRP A 350
TYR A 948
 None
 1.40A 5oh1A-3ogrA:
undetectable		 5oh1A-3ogrA:
6.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_A_9V2A202_0
(CEREBLON ISOFORM 4)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 7 PRO A  69
PHE A  70
TRP A 350
TYR A 948
 None
 1.45A 5oh3A-3ogrA:
undetectable		 5oh3A-3ogrA:
8.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYE_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		5 / 12 GLU A 298
VAL A 297
SER A 295
GLN A 217
GLY A 243
 GAL  A1024 (-2.7A)
None
None
None
None
 1.15A 5syeB-3ogrA:
undetectable		 5syeB-3ogrA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 5 PHE A 327
PHE A 299
LEU A 296
PHE A 294
 None
 0.92A 5wauC-3ogrA:
undetectable
5wauJ-3ogrA:
undetectable		 5wauC-3ogrA:
14.48
5wauJ-3ogrA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 5 PHE A 327
PHE A 299
LEU A 296
PHE A 294
 None
 0.95A 5wauc-3ogrA:
undetectable
5wauj-3ogrA:
undetectable		 5wauc-3ogrA:
14.48
5wauj-3ogrA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA502_1
(CYTOCHROME P450 2C9)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		5 / 12 LEU A  77
VAL A  81
VAL A  67
GLY A 346
LEU A 353
 None
 1.12A 5x24A-3ogrA:
undetectable		 5x24A-3ogrA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_D_SALD201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 5 PRO A 261
GLY A 263
TYR A 260
VAL A 319
 None
None
GAL  A1024 (-4.4A)
None
 1.00A 5x80C-3ogrA:
undetectable
5x80D-3ogrA:
undetectable		 5x80C-3ogrA:
10.37
5x80D-3ogrA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 5 PHE A 327
PHE A 299
LEU A 296
PHE A 294
 None
 0.92A 5xdqC-3ogrA:
undetectable
5xdqJ-3ogrA:
undetectable		 5xdqC-3ogrA:
14.48
5xdqJ-3ogrA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 5 PHE A 327
PHE A 299
LEU A 296
PHE A 294
 None
 0.95A 5xdqP-3ogrA:
undetectable
5xdqW-3ogrA:
undetectable		 5xdqP-3ogrA:
14.48
5xdqW-3ogrA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XPR_A_K86A1201_2
(ENDOTHELIN B
RECEPTOR,ENDOLYSIN,E
NDOTHELIN B RECEPTOR)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 4 ASP A 221
PRO A 197
GLU A 198
TYR A 166
 None
 1.26A 5xprA-3ogrA:
1.5		 5xprA-3ogrA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		5 / 10 ILE A 641
LEU A 620
LEU A 632
ALA A 663
LEU A 651
 None
 1.13A 5y7pB-3ogrA:
undetectable		 5y7pB-3ogrA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_D_CHDD401_0
(BILE SALT HYDROLASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		5 / 10 ILE A 641
LEU A 620
LEU A 632
ALA A 663
LEU A 651
 None
 1.17A 5y7pD-3ogrA:
undetectable		 5y7pD-3ogrA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_H_CHDH401_0
(BILE SALT HYDROLASE)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		5 / 10 ILE A 641
LEU A 620
LEU A 632
ALA A 663
LEU A 651
 None
 1.16A 5y7pH-3ogrA:
undetectable		 5y7pH-3ogrA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 6 PHE A 327
PHE A 299
LEU A 296
PHE A 294
 None
 0.98A 5z84P-3ogrA:
undetectable
5z84W-3ogrA:
undetectable		 5z84P-3ogrA:
14.48
5z84W-3ogrA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 6 PHE A 327
PHE A 299
LEU A 296
PHE A 294
 None
 1.05A 5z85P-3ogrA:
undetectable
5z85W-3ogrA:
undetectable		 5z85P-3ogrA:
14.48
5z85W-3ogrA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 6 PHE A 327
PHE A 299
LEU A 296
PHE A 294
 None
 0.91A 5z86C-3ogrA:
undetectable
5z86J-3ogrA:
undetectable		 5z86C-3ogrA:
14.48
5z86J-3ogrA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 6 PHE A 327
PHE A 299
LEU A 296
PHE A 294
 None
 0.94A 5z86P-3ogrA:
undetectable
5z86W-3ogrA:
undetectable		 5z86P-3ogrA:
14.48
5z86W-3ogrA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 6 PHE A 327
PHE A 299
LEU A 296
PHE A 294
 None
 0.96A 5zcoP-3ogrA:
undetectable
5zcoW-3ogrA:
undetectable		 5zcoP-3ogrA:
14.48
5zcoW-3ogrA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 6 PHE A 327
PHE A 299
LEU A 296
PHE A 294
 None
 0.93A 5zcpC-3ogrA:
undetectable
5zcpJ-3ogrA:
undetectable		 5zcpC-3ogrA:
14.48
5zcpJ-3ogrA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 6 PHE A 327
PHE A 299
LEU A 296
PHE A 294
 None
 0.97A 5zcpP-3ogrA:
undetectable
5zcpW-3ogrA:
undetectable		 5zcpP-3ogrA:
14.48
5zcpW-3ogrA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 3ogr BETA-GALACTOSIDASE
(Trichoderma
reesei) 		4 / 7 ILE A 193
GLU A  58
HIS A  56
VAL A  46
 None
 0.98A 6j20A-3ogrA:
undetectable		 6j20A-3ogrA:
17.81