SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oh8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)
(Corynebacterium
glutamicum) 		4 / 6 PHE A   8
LEU A 133
VAL A  16
MET A  15
 None
 0.91A 1hk1A-3oh8A:
undetectable		 1hk1A-3oh8A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)
(Corynebacterium
glutamicum) 		4 / 7 PHE A   8
LEU A 133
VAL A  16
MET A  15
 None
 0.92A 1hk3A-3oh8A:
undetectable		 1hk3A-3oh8A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_2
(HIV-1 PROTEASE)		 3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)
(Corynebacterium
glutamicum) 		3 / 3 ARG A 226
THR A 233
VAL A 230
 None
 1.01A 1hxbA-3oh8A:
undetectable		 1hxbA-3oh8A:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)
(Corynebacterium
glutamicum) 		4 / 5 ASP A 347
GLU A 131
THR A 139
LEU A 136
 None
 0.91A 1u18B-3oh8A:
undetectable		 1u18B-3oh8A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_1
(CES1 PROTEIN)		 3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)
(Corynebacterium
glutamicum) 		5 / 12 GLY A 312
GLY A 313
VAL A 306
LEU A 317
LEU A 440
 None
 1.15A 1ya4B-3oh8A:
undetectable		 1ya4B-3oh8A:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)
(Corynebacterium
glutamicum) 		4 / 5 PHE A  75
PHE A  96
HIS A  20
VAL A  26
 None
 1.12A 2lh6A-3oh8A:
undetectable		 2lh6A-3oh8A:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)
(Corynebacterium
glutamicum) 		3 / 3 TYR A 124
GLU A 439
THR A 346
 None
 1.03A 2y7hB-3oh8A:
undetectable		 2y7hB-3oh8A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)
(Corynebacterium
glutamicum) 		5 / 10 GLN A 168
HIS A 172
VAL A 174
VAL A 150
LEU A 163
 None
 1.31A 3czvB-3oh8A:
undetectable		 3czvB-3oh8A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_C_MTXC164_2
(DIHYDROFOLATE
REDUCTASE)		 3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)
(Corynebacterium
glutamicum) 		4 / 4 ILE A 105
ARG A 428
ILE A   9
THR A   5
 None
 1.07A 3ia4C-3oh8A:
undetectable		 3ia4C-3oh8A:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB0_A_DIFA701_1
(LACTOTRANSFERRIN)		 3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)
(Corynebacterium
glutamicum) 		4 / 4 PRO A  31
TYR A 124
GLY A 120
THR A 119
 None
 1.40A 3ib0A-3oh8A:
undetectable		 3ib0A-3oh8A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NAI_C_URFC521_1
(RNA DEPENDENT RNA
POLYMERASE)		 3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)
(Corynebacterium
glutamicum) 		4 / 5 ARG A 138
ASP A 344
ASP A 347
ASP A 343
 None
 1.26A 3naiC-3oh8A:
undetectable		 3naiC-3oh8A:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)
(Corynebacterium
glutamicum) 		3 / 3 ASN A 372
ALA A 373
LYS A 329
 None
 0.85A 3runA-3oh8A:
undetectable		 3runA-3oh8A:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_2
(NEURAMINIDASE)		 3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)
(Corynebacterium
glutamicum) 		4 / 5 LEU A 239
ASP A 200
ARG A 187
ILE A 175
 None
 1.40A 4mwrA-3oh8A:
undetectable		 4mwrA-3oh8A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)
(Corynebacterium
glutamicum) 		5 / 10 ALA A 165
THR A 164
ALA A 162
GLY A 170
THR A 169
 None
 1.03A 4qvyK-3oh8A:
undetectable
4qvyL-3oh8A:
undetectable		 4qvyK-3oh8A:
20.59
4qvyL-3oh8A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)
(Corynebacterium
glutamicum) 		5 / 10 ALA A 165
THR A 164
ALA A 162
GLY A 170
THR A 169
 None
 1.02A 4qvyY-3oh8A:
undetectable
4qvyZ-3oh8A:
undetectable		 4qvyY-3oh8A:
20.59
4qvyZ-3oh8A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)
(Corynebacterium
glutamicum) 		5 / 12 LEU A   3
GLN A 450
ILE A 454
GLU A 486
SER A 494
 None
 1.48A 4r88D-3oh8A:
undetectable		 4r88D-3oh8A:
25.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)
(Corynebacterium
glutamicum) 		5 / 12 LEU A   3
GLN A 450
ILE A 454
GLU A 486
SER A 494
 None
 1.49A 4r88F-3oh8A:
2.4		 4r88F-3oh8A:
25.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_A_032A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)
(Corynebacterium
glutamicum) 		4 / 5 ILE A 175
VAL A 174
PHE A 143
CYH A 246
 None
 1.33A 4rzvA-3oh8A:
undetectable		 4rzvA-3oh8A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WAN_C_ACTC303_0
(BRANCHPOINT-BRIDGING
PROTEIN)		 3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)
(Corynebacterium
glutamicum) 		3 / 3 ASP A 343
ARG A 311
PRO A  32
 None
 0.87A 4wanC-3oh8A:
undetectable		 4wanC-3oh8A:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		 3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)
(Corynebacterium
glutamicum) 		4 / 7 PRO A 488
VAL A 491
ILE A 495
VAL A  93
 None
 0.57A 5bmvC-3oh8A:
4.8		 5bmvC-3oh8A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)
(Corynebacterium
glutamicum) 		3 / 3 ALA A 419
ASN A 422
LEU A 423
 None
 0.50A 5i1oA-3oh8A:
undetectable		 5i1oA-3oh8A:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_D_ZOLD401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)
(Corynebacterium
glutamicum) 		4 / 7 LEU A 104
ASP A 107
GLN A 126
GLN A 450
 None
 1.20A 6g31D-3oh8A:
undetectable		 6g31D-3oh8A:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)
(Corynebacterium
glutamicum) 		4 / 6 LEU A 104
ASP A 107
GLN A 126
GLN A 450
 None
 1.08A 6g31J-3oh8A:
undetectable		 6g31J-3oh8A:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)
(Corynebacterium
glutamicum) 		4 / 8 TRP A 336
ASP A 261
ARG A 262
HIS A 260
 None
 1.32A 6mn4C-3oh8A:
undetectable		 6mn4C-3oh8A:
21.76