SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ohe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 3ohe HISTIDINE TRIAD
(HIT) PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 6 LEU A  64
SER A  61
LEU A  57
LEU A 135
 None
 1.03A 3f33A-3oheA:
undetectable		 3f33A-3oheA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3ohe HISTIDINE TRIAD
(HIT) PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		3 / 3 VAL A  23
SER A  18
LEU A  36
 None
 0.62A 3n8xA-3oheA:
undetectable		 3n8xA-3oheA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_C_FLPC701_1
(CYCLOOXYGENASE-2)		 3ohe HISTIDINE TRIAD
(HIT) PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 VAL A  23
LEU A  71
LEU A  64
VAL A 124
LEU A 132
 None
 0.99A 3pghC-3oheA:
undetectable		 3pghC-3oheA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3ohe HISTIDINE TRIAD
(HIT) PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 8 PRO A  32
VAL A  34
LEU A  25
LEU A  15
 None
 0.81A 3u5kA-3oheA:
undetectable		 3u5kA-3oheA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_1
(METHYLTRANSFERASE
MPPJ)		 3ohe HISTIDINE TRIAD
(HIT) PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		3 / 3 ARG A  96
ASP A  28
ASP A  11
 None
GOL  A 139 (-3.6A)
GOL  A 140 (-3.7A)
 0.75A 4kicB-3oheA:
undetectable		 4kicB-3oheA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_A_IBPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ohe HISTIDINE TRIAD
(HIT) PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 10 VAL A 124
VAL A  34
LEU A  25
GLY A  67
LEU A 128
 None
 1.08A 4ph9A-3oheA:
undetectable		 4ph9A-3oheA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_B_IBPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ohe HISTIDINE TRIAD
(HIT) PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 10 VAL A 124
VAL A  34
LEU A  25
GLY A  67
LEU A 128
 None
 1.08A 4ph9B-3oheA:
undetectable		 4ph9B-3oheA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 3ohe HISTIDINE TRIAD
(HIT) PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 LEU A  57
GLN A  88
ILE A  46
ALA A  81
ILE A  43
 None
 1.20A 4rp8C-3oheA:
undetectable		 4rp8C-3oheA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 3ohe HISTIDINE TRIAD
(HIT) PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 7 LEU A 135
GLU A  60
SER A  18
VAL A  37
 None
 1.05A 4tvtA-3oheA:
undetectable		 4tvtA-3oheA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZBD_A_TRPA501_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 3ohe HISTIDINE TRIAD
(HIT) PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 10 HIS A  92
LEU A   8
ASP A  11
VAL A  86
GLY A  83
 GOL  A 140 (-4.4A)
GOL  A 140 (-4.3A)
GOL  A 140 (-3.7A)
GOL  A 140 (-4.7A)
None
 1.47A 5zbdA-3oheA:
undetectable		 5zbdA-3oheA:
13.42