SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ohg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_B_ADNB2604_1
(5'-NUCLEOTIDASE)
3ohg UNCHARACTERIZED
PROTEIN FROM DUF2233
FAMILY

(Bacteroides
ovatus)
5 / 10 SER A 274
GLY A 272
ARG A 239
GLY A 271
ASP A 270
EDO  A 414 ( 4.0A)
SO4  A 402 (-3.6A)
SO4  A 402 (-2.9A)
None
EDO  A 414 ( 4.7A)
1.27A 1ho5B-3ohgA:
undetectable
1ho5B-3ohgA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_B_486B1_2
(GLUCOCORTICOID
RECEPTOR)
3ohg UNCHARACTERIZED
PROTEIN FROM DUF2233
FAMILY

(Bacteroides
ovatus)
5 / 12 GLY A 193
GLY A 192
VAL A 163
LEU A 197
MET A 258
None
1.26A 3h52B-3ohgA:
undetectable
3h52B-3ohgA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAV_A_SRYA403_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)
3ohg UNCHARACTERIZED
PROTEIN FROM DUF2233
FAMILY

(Bacteroides
ovatus)
4 / 8 ASP A  96
SER A 107
ASP A  97
ASP A 132
EDO  A 406 ( 2.9A)
EDO  A 406 ( 3.8A)
EDO  A 413 (-3.4A)
None
1.09A 3havA-3ohgA:
2.0
3havA-3ohgA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA193_1
(DIHYDROFOLATE
REDUCTASE)
3ohg UNCHARACTERIZED
PROTEIN FROM DUF2233
FAMILY

(Bacteroides
ovatus)
4 / 5 ASP A 132
LEU A 269
PRO A  92
PHE A  90
None
1.23A 3s3vA-3ohgA:
undetectable
3s3vA-3ohgA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_1
(MNMC2)
3ohg UNCHARACTERIZED
PROTEIN FROM DUF2233
FAMILY

(Bacteroides
ovatus)
4 / 6 GLY A 170
GLU A 171
ASP A 227
ASN A  86
None
EDO  A 419 ( 3.7A)
None
EDO  A 419 (-3.9A)
0.95A 3vywC-3ohgA:
undetectable
3vywC-3ohgA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1004_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)
3ohg UNCHARACTERIZED
PROTEIN FROM DUF2233
FAMILY

(Bacteroides
ovatus)
5 / 11 VAL A 125
ALA A 118
LEU A 310
LEU A 277
PHE A  79
None
0.91A 3zosA-3ohgA:
1.8
3zosB-3ohgA:
1.8
3zosA-3ohgA:
21.97
3zosB-3ohgA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZS3_A_ACTA1224_0
(THAUMATIN-LIKE
PROTEIN)
3ohg UNCHARACTERIZED
PROTEIN FROM DUF2233
FAMILY

(Bacteroides
ovatus)
4 / 5 SER A 108
THR A 306
TYR A 134
ASP A 270
None
None
None
EDO  A 414 ( 4.7A)
1.29A 3zs3A-3ohgA:
undetectable
3zs3A-3ohgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA201_1
(GALNAC/GAL-SPECIFIC
LECTIN)
3ohg UNCHARACTERIZED
PROTEIN FROM DUF2233
FAMILY

(Bacteroides
ovatus)
5 / 9 ASN A 307
GLY A 192
GLY A 193
VAL A 141
ASP A 270
None
None
None
CL  A 400 (-4.3A)
EDO  A 414 ( 4.7A)
1.23A 5f8yA-3ohgA:
undetectable
5f8yA-3ohgA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA203_1
(GALNAC/GAL-SPECIFIC
LECTIN)
3ohg UNCHARACTERIZED
PROTEIN FROM DUF2233
FAMILY

(Bacteroides
ovatus)
5 / 9 GLY A 192
GLY A 193
VAL A 141
ASP A 270
ASN A 307
None
None
CL  A 400 (-4.3A)
EDO  A 414 ( 4.7A)
None
1.22A 5f8yA-3ohgA:
undetectable
5f8yA-3ohgA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB202_1
(GALNAC/GAL-SPECIFIC
LECTIN)
3ohg UNCHARACTERIZED
PROTEIN FROM DUF2233
FAMILY

(Bacteroides
ovatus)
5 / 9 GLY A 192
GLY A 193
VAL A 141
ASP A 270
ASN A 307
None
None
CL  A 400 (-4.3A)
EDO  A 414 ( 4.7A)
None
1.25A 5f8yB-3ohgA:
undetectable
5f8yB-3ohgA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB203_1
(GALNAC/GAL-SPECIFIC
LECTIN)
3ohg UNCHARACTERIZED
PROTEIN FROM DUF2233
FAMILY

(Bacteroides
ovatus)
5 / 9 ASN A 307
GLY A 192
GLY A 193
VAL A 141
ASP A 270
None
None
None
CL  A 400 (-4.3A)
EDO  A 414 ( 4.7A)
1.20A 5f8yB-3ohgA:
undetectable
5f8yB-3ohgA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)
3ohg UNCHARACTERIZED
PROTEIN FROM DUF2233
FAMILY

(Bacteroides
ovatus)
3 / 3 GLY A 201
GLN A 204
LYS A 259
None
0.96A 5imsB-3ohgA:
undetectable
5imsB-3ohgA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_2
(PROTEASE PR5-SQV)
3ohg UNCHARACTERIZED
PROTEIN FROM DUF2233
FAMILY

(Bacteroides
ovatus)
5 / 11 LEU A  85
ALA A  81
ILE A 279
GLY A 128
ILE A  83
None
1.12A 5kr2B-3ohgA:
undetectable
5kr2B-3ohgA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)
3ohg UNCHARACTERIZED
PROTEIN FROM DUF2233
FAMILY

(Bacteroides
ovatus)
5 / 12 GLY A 271
GLY A 272
ILE A  78
GLN A  76
LEU A 249
None
SO4  A 402 (-3.6A)
None
None
None
0.94A 5l0zA-3ohgA:
undetectable
5l0zA-3ohgA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)
3ohg UNCHARACTERIZED
PROTEIN FROM DUF2233
FAMILY

(Bacteroides
ovatus)
5 / 12 PRO A  33
ILE A  78
ASP A  53
VAL A  42
THR A 256
EDO  A 403 ( 4.9A)
None
None
EDO  A 403 ( 4.8A)
None
1.31A 5tiwB-3ohgA:
undetectable
5tiwB-3ohgA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3ohg UNCHARACTERIZED
PROTEIN FROM DUF2233
FAMILY

(Bacteroides
ovatus)
3 / 3 GLY A 223
VAL A 129
MET A 309
None
0.48A 5ycpA-3ohgA:
undetectable
5ycpA-3ohgA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_2
(PROTEASE)
3ohg UNCHARACTERIZED
PROTEIN FROM DUF2233
FAMILY

(Bacteroides
ovatus)
3 / 3 LEU A 269
ASP A 237
ILE A  78
None
0.64A 6dh0B-3ohgA:
undetectable
6dh0B-3ohgA:
16.67