SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ohn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA444_1
(ALPHA AMYLASE)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		4 / 7 TYR A 144
ASN A 636
TYR A 650
GLY A 638
 None
 1.17A 1mxgA-3ohnA:
undetectable		 1mxgA-3ohnA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_B_SALB1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		5 / 10 ILE A 259
GLY A 258
PHE A 285
THR A 537
ILE A 303
 None
 1.26A 2y7wB-3ohnA:
undetectable		 2y7wB-3ohnA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		4 / 8 GLY A 613
ILE A 645
SER A 618
THR A 621
 None
 0.86A 2yoeB-3ohnA:
undetectable
2yoeC-3ohnA:
undetectable		 2yoeB-3ohnA:
20.87
2yoeC-3ohnA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		4 / 5 ILE A 382
ARG A 415
MET A 396
THR A 397
 None
 1.30A 3abkN-3ohnA:
undetectable
3abkW-3ohnA:
undetectable		 3abkN-3ohnA:
21.45
3abkW-3ohnA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		3 / 3 THR A 487
SER A 503
LYS A 483
 None
 1.19A 3aocC-3ohnA:
undetectable		 3aocC-3ohnA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		4 / 7 SER A 496
LEU A 551
LEU A 532
THR A 523
 None
 0.86A 3cfqA-3ohnA:
4.2
3cfqB-3ohnA:
4.4		 3cfqA-3ohnA:
11.07
3cfqB-3ohnA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B304_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		4 / 5 THR A 354
SER A 332
SER A 240
ARG A 330
 None
 1.39A 3hlwB-3ohnA:
undetectable		 3hlwB-3ohnA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		4 / 4 GLY A 367
TYR A 366
GLY A 381
ASP A 395
 None
 0.75A 3kl3A-3ohnA:
undetectable		 3kl3A-3ohnA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T8N_D_EDTD135_0
(STEROID
DELTA-ISOMERASE)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		5 / 11 THR A 263
GLY A 262
PRO A 282
THR A 621
GLY A 622
 None
 1.02A 3t8nD-3ohnA:
undetectable
3t8nF-3ohnA:
undetectable		 3t8nD-3ohnA:
12.50
3t8nF-3ohnA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T8N_D_EDTD135_0
(STEROID
DELTA-ISOMERASE)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		5 / 11 THR A 621
GLY A 622
THR A 263
GLY A 262
PRO A 282
 None
 1.01A 3t8nD-3ohnA:
undetectable
3t8nF-3ohnA:
undetectable		 3t8nD-3ohnA:
12.50
3t8nF-3ohnA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TVX_B_PNXB902_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4A)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		4 / 7 TYR A 276
ASN A 145
ILE A 290
GLN A 167
 None
 1.23A 3tvxB-3ohnA:
undetectable		 3tvxB-3ohnA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		4 / 7 SER A 496
LEU A 551
LEU A 532
THR A 523
 None
 0.88A 4ikkA-3ohnA:
4.3
4ikkB-3ohnA:
4.3		 4ikkA-3ohnA:
11.84
4ikkB-3ohnA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		3 / 3 SER A 296
TYR A 222
PRO A 254
 None
 0.86A 4k8cA-3ohnA:
undetectable		 4k8cA-3ohnA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		3 / 3 SER A 296
TYR A 222
PRO A 254
 None
 0.88A 4kahA-3ohnA:
undetectable		 4kahA-3ohnA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		3 / 3 SER A 296
TYR A 222
PRO A 254
 None
 0.87A 4kahB-3ohnA:
undetectable		 4kahB-3ohnA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		3 / 3 SER A 296
TYR A 222
PRO A 254
 None
 0.87A 4kanA-3ohnA:
undetectable		 4kanA-3ohnA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		3 / 3 SER A 296
TYR A 222
PRO A 254
 None
 0.85A 4kanB-3ohnA:
undetectable		 4kanB-3ohnA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		3 / 3 SER A 296
TYR A 222
PRO A 254
 None
 0.85A 4kbeA-3ohnA:
undetectable		 4kbeA-3ohnA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		3 / 3 SER A 296
TYR A 222
PRO A 254
 None
 0.84A 4kbeB-3ohnA:
undetectable		 4kbeB-3ohnA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		3 / 3 TYR A 441
ARG A 435
SER A 413
 None
 0.96A 4khpI-3ohnA:
undetectable
4khpJ-3ohnA:
undetectable		 4khpI-3ohnA:
11.91
4khpJ-3ohnA:
10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA2)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		4 / 6 SER A 319
ARG A 415
GLY A 381
GLY A 383
 None
 0.95A 4koeA-3ohnA:
undetectable
4koeB-3ohnA:
undetectable
4koeC-3ohnA:
undetectable		 4koeA-3ohnA:
21.85
4koeB-3ohnA:
21.85
4koeC-3ohnA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		3 / 3 SER A 296
TYR A 222
PRO A 254
 None
 0.87A 4lbgA-3ohnA:
undetectable		 4lbgA-3ohnA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		3 / 3 SER A 296
TYR A 222
PRO A 254
 None
 0.88A 4lbgB-3ohnA:
undetectable		 4lbgB-3ohnA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_B_SAMB601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		5 / 12 ALA A 611
GLY A 612
GLY A 613
ASP A 615
GLY A 609
 None
 0.82A 4obwB-3ohnA:
undetectable		 4obwB-3ohnA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_1
(PROTEASE)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		5 / 12 ASP A 274
ILE A 303
THR A 314
VAL A 315
VAL A 280
 None
 1.00A 4q5mA-3ohnA:
undetectable		 4q5mA-3ohnA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		4 / 6 GLY A 381
GLY A 383
SER A 319
ARG A 415
 None
 0.88A 4z53A-3ohnA:
undetectable
4z53B-3ohnA:
undetectable		 4z53A-3ohnA:
21.31
4z53B-3ohnA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C6P_A_4YHA601_1
(PROTEIN C)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		4 / 6 ALA A 611
SER A 620
SER A 640
PRO A 282
 None
 0.72A 5c6pA-3ohnA:
undetectable		 5c6pA-3ohnA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		4 / 8 PRO A 404
PHE A 442
ASN A 475
SER A 401
 None
 0.95A 5l1fA-3ohnA:
undetectable
5l1fB-3ohnA:
undetectable		 5l1fA-3ohnA:
21.50
5l1fB-3ohnA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2T_A_6ZZA900_2
(CYCLIN-DEPENDENT
KINASE 6)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		3 / 3 LYS A 304
GLN A 152
ASN A 153
 None
 1.08A 5l2tA-3ohnA:
undetectable		 5l2tA-3ohnA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		5 / 10 ASP A 446
LEU A 371
ALA A 377
THR A 334
GLY A 230
 None
 1.26A 5m5cE-3ohnA:
undetectable		 5m5cE-3ohnA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_C_DAHC60_1
(PUTATIVE CYTOCHROME
C)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		4 / 6 GLN A 542
HIS A 504
ASN A 512
LEU A 536
 None
 1.30A 5xdhA-3ohnA:
undetectable
5xdhC-3ohnA:
undetectable		 5xdhA-3ohnA:
9.71
5xdhC-3ohnA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F32_B_ACTB602_0
(AMINE OXIDASE LKCE)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		4 / 6 ASN A 149
TYR A 649
VAL A 151
THR A 263
 None
 1.36A 6f32B-3ohnA:
undetectable		 6f32B-3ohnA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F32_B_ACTB602_0
(AMINE OXIDASE LKCE)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		4 / 6 ASN A 165
TYR A 163
VAL A 266
THR A 267
 None
 1.30A 6f32B-3ohnA:
undetectable		 6f32B-3ohnA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		4 / 5 GLN A 516
THR A 314
THR A 506
GLY A 502
 None
 1.11A 6gbnC-3ohnA:
undetectable		 6gbnC-3ohnA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_N_PCFN606_0
(CYTOCHROME B)		 3ohn OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		5 / 12 ALA A 264
TYR A 623
THR A 625
VAL A 266
VAL A 301
 None
 1.20A 6hu9N-3ohnA:
undetectable		 6hu9N-3ohnA:
20.83