SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ohp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FKB_A_RAPA108_1 (FK506 BINDING PROTEIN)	3ohp	HYPOXANTHINE PHOSPHORIBOSYLTRANSF ERASE (Vibrio cholerae)	5 / 12	GLN A 12 GLU A 13 VAL A 14 ILE A 18 PHE A 47	None	1.22A	1fkbA-3ohpA: undetectable	1fkbA-3ohpA: 20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HJO_B_EAAB211_1 (GLUTATHIONE S-TRANSFERASE P)	3ohp	HYPOXANTHINE PHOSPHORIBOSYLTRANSF ERASE (Vibrio cholerae)	4 / 8	VAL A 14 VAL A 46 ILE A 147 VAL A 152	None	0.75A	3hjoB-3ohpA: undetectable	3hjoB-3ohpA: 21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EM0_B_KANB302_1 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349)	3ohp	HYPOXANTHINE PHOSPHORIBOSYLTRANSF ERASE (Vibrio cholerae)	5 / 11	LEU A 40 THR A 106 LEU A 114 ARG A 117 VAL A 79	None	1.33A	4em0B-3ohpA: 0.0	4em0B-3ohpA: 20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IAR_A_ERMA2001_1 (CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 1B AND E. COLI SOLUBLE CYTOCHROME B562)	3ohp	HYPOXANTHINE PHOSPHORIBOSYLTRANSF ERASE (Vibrio cholerae)	5 / 12	ASP A 87 VAL A 36 MET A 48 LEU A 40 PHE A 63	None	1.35A	4iarA-3ohpA: undetectable	4iarA-3ohpA: 18.62

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FKB_A_RAPA108_1","FK506 BINDING PROTEIN","3ohp","HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE","Vibrio cholerae",5,"GLN A  12;GLU A  13;VAL A  14;ILE A  18;PHE A  47","None","1.22A","1fkbA-3ohpA:undetectable","1fkbA-3ohpA:20.32"],["3HJO_B_EAAB211_1","GLUTATHIONE S-TRANSFERASE P","3ohp","HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE","Vibrio cholerae",4,"VAL A  14;VAL A  46;ILE A 147;VAL A 152","None","0.75A","3hjoB-3ohpA:undetectable","3hjoB-3ohpA:21.50"],["4EM0_B_KANB302_1","UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349","3ohp","HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE","Vibrio cholerae",5,"LEU A  40;THR A 106;LEU A 114;ARG A 117;VAL A  79","None","1.33A","4em0B-3ohpA:0.0","4em0B-3ohpA:20.62"],["4IAR_A_ERMA2001_1","CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 1B AND E. COLI SOLUBLE CYTOCHROME B562","3ohp","HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE","Vibrio cholerae",5,"ASP A  87;VAL A  36;MET A  48;LEU A  40;PHE A  63","None","1.35A","4iarA-3ohpA:undetectable","4iarA-3ohpA:18.62"]]