SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ohu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE201_1
(PROTEIN S100-A4)		 3ohu TRANSCRIPTION
REGULATOR PROTEIN
BACH2
(Homo
sapiens) 		4 / 7 GLY A  88
PHE A  87
CYH A  58
PHE A  62
 None
 1.13A 3ko0D-3ohuA:
undetectable
3ko0E-3ohuA:
undetectable		 3ko0D-3ohuA:
24.41
3ko0E-3ohuA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA406_0
(THIOREDOXIN
REDUCTASE)		 3ohu TRANSCRIPTION
REGULATOR PROTEIN
BACH2
(Homo
sapiens) 		3 / 3 HIS A 119
SER A  59
ARG A 117
 None
 0.98A 5u63A-3ohuA:
undetectable		 5u63A-3ohuA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_2
(TUBULIN BETA CHAIN)		 3ohu TRANSCRIPTION
REGULATOR PROTEIN
BACH2
(Homo
sapiens) 		4 / 6 LEU A  55
LEU A  78
THR A  40
ARG A  45
 None
 1.07A 6ew0G-3ohuA:
undetectable		 6ew0G-3ohuA:
21.26