SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ohw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 3ohw PHYCOBILISOME LCM
CORE-MEMBRANE LINKER
POLYPEPTIDE
(Synechocystis
sp.
PCC
6803) 		4 / 7 PHE B 791
GLY B 782
ILE B 778
GLY B 804
 None
 0.81A 11gsB-3ohwB:
undetectable		 11gsB-3ohwB:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 3ohw PHYCOBILISOME LCM
CORE-MEMBRANE LINKER
POLYPEPTIDE
(Synechocystis
sp.
PCC
6803) 		4 / 7 PHE B 834
GLY B 782
ILE B 778
GLY B 836
 None
 0.87A 11gsB-3ohwB:
undetectable		 11gsB-3ohwB:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E73_M_ASCM995_0
(MYROSINASE MA1)		 3ohw PHYCOBILISOME LCM
CORE-MEMBRANE LINKER
POLYPEPTIDE
(Synechocystis
sp.
PCC
6803) 		4 / 6 ILE B 755
TYR B 743
PHE B 747
PHE B 777
 None
 1.33A 1e73M-3ohwB:
undetectable		 1e73M-3ohwB:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HBP_A_RTLA184_0
(RETINOL BINDING
PROTEIN)		 3ohw PHYCOBILISOME LCM
CORE-MEMBRANE LINKER
POLYPEPTIDE
(Synechocystis
sp.
PCC
6803) 		5 / 11 LEU B 814
ALA B 833
ALA B 837
MET B 838
LEU B 809
 None
 1.32A 1hbpA-3ohwB:
undetectable		 1hbpA-3ohwB:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_A_FOLA605_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3ohw PHYCOBILISOME LCM
CORE-MEMBRANE LINKER
POLYPEPTIDE
(Synechocystis
sp.
PCC
6803) 		5 / 12 VAL B 735
LEU B 781
LEU B 763
SER B 765
ILE B 756
 None
 1.02A 1qzfA-3ohwB:
undetectable		 1qzfA-3ohwB:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_B_FOLB609_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3ohw PHYCOBILISOME LCM
CORE-MEMBRANE LINKER
POLYPEPTIDE
(Synechocystis
sp.
PCC
6803) 		5 / 12 VAL B 735
LEU B 781
LEU B 763
SER B 765
ILE B 756
 None
 1.01A 1qzfB-3ohwB:
undetectable		 1qzfB-3ohwB:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_C_FOLC613_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3ohw PHYCOBILISOME LCM
CORE-MEMBRANE LINKER
POLYPEPTIDE
(Synechocystis
sp.
PCC
6803) 		5 / 12 VAL B 735
LEU B 781
LEU B 763
SER B 765
ILE B 756
 None
 1.02A 1qzfC-3ohwB:
undetectable		 1qzfC-3ohwB:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_D_FOLD617_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3ohw PHYCOBILISOME LCM
CORE-MEMBRANE LINKER
POLYPEPTIDE
(Synechocystis
sp.
PCC
6803) 		5 / 12 VAL B 735
LEU B 781
LEU B 763
SER B 765
ILE B 756
 None
 1.02A 1qzfD-3ohwB:
undetectable		 1qzfD-3ohwB:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_E_FOLE621_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3ohw PHYCOBILISOME LCM
CORE-MEMBRANE LINKER
POLYPEPTIDE
(Synechocystis
sp.
PCC
6803) 		5 / 12 VAL B 735
LEU B 781
LEU B 763
SER B 765
ILE B 756
 None
 1.00A 1qzfE-3ohwB:
undetectable		 1qzfE-3ohwB:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_A_MTXA605_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 3ohw PHYCOBILISOME LCM
CORE-MEMBRANE LINKER
POLYPEPTIDE
(Synechocystis
sp.
PCC
6803) 		5 / 12 VAL B 735
LEU B 781
LEU B 763
SER B 765
ILE B 756
 None
 1.06A 2oipA-3ohwB:
undetectable		 2oipA-3ohwB:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 3ohw PHYCOBILISOME LCM
CORE-MEMBRANE LINKER
POLYPEPTIDE
(Synechocystis
sp.
PCC
6803) 		5 / 12 TYR B 792
LEU B 831
ILE B 835
PHE B 808
HIS B 807
 None
 1.39A 2qo4A-3ohwB:
undetectable		 2qo4A-3ohwB:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_D_MTXD615_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 3ohw PHYCOBILISOME LCM
CORE-MEMBRANE LINKER
POLYPEPTIDE
(Synechocystis
sp.
PCC
6803) 		5 / 12 VAL B 735
LEU B 781
LEU B 763
SER B 765
ILE B 756
 None
 1.04A 3hj3D-3ohwB:
undetectable		 3hj3D-3ohwB:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3ohw PHYCOBILISOME LCM
CORE-MEMBRANE LINKER
POLYPEPTIDE
(Synechocystis
sp.
PCC
6803) 		4 / 7 GLU B 764
ILE B 756
HIS B 807
VAL B 839
 None
 1.11A 4a97D-3ohwB:
undetectable		 4a97D-3ohwB:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3ohw PHYCOBILISOME LCM
CORE-MEMBRANE LINKER
POLYPEPTIDE
(Synechocystis
sp.
PCC
6803) 		4 / 6 GLU B 764
ILE B 756
HIS B 807
VAL B 839
 None
 1.20A 4a97I-3ohwB:
undetectable		 4a97I-3ohwB:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_A_MTXA603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 3ohw PHYCOBILISOME LCM
CORE-MEMBRANE LINKER
POLYPEPTIDE
(Synechocystis
sp.
PCC
6803) 		6 / 12 VAL B 735
LEU B 781
LEU B 763
LYS B 766
SER B 765
ILE B 756
 None
 1.14A 4ky8A-3ohwB:
undetectable		 4ky8A-3ohwB:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_C_MTXC603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 3ohw PHYCOBILISOME LCM
CORE-MEMBRANE LINKER
POLYPEPTIDE
(Synechocystis
sp.
PCC
6803) 		6 / 12 VAL B 735
LEU B 781
LEU B 763
LYS B 766
SER B 765
ILE B 756
 None
 1.17A 4ky8C-3ohwB:
undetectable		 4ky8C-3ohwB:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_D_MTXD603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 3ohw PHYCOBILISOME LCM
CORE-MEMBRANE LINKER
POLYPEPTIDE
(Synechocystis
sp.
PCC
6803) 		5 / 12 VAL B 735
LEU B 781
LEU B 763
LYS B 766
ILE B 756
 None
 1.12A 4ky8D-3ohwB:
undetectable		 4ky8D-3ohwB:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_E_MTXE603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 3ohw PHYCOBILISOME LCM
CORE-MEMBRANE LINKER
POLYPEPTIDE
(Synechocystis
sp.
PCC
6803) 		6 / 12 VAL B 735
LEU B 781
LEU B 763
LYS B 766
SER B 765
ILE B 756
 None
 1.14A 4ky8E-3ohwB:
undetectable		 4ky8E-3ohwB:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 3ohw PHYCOBILISOME LCM
CORE-MEMBRANE LINKER
POLYPEPTIDE
(Synechocystis
sp.
PCC
6803) 		4 / 6 THR B 783
SER B 784
TYR B 787
GLY B 780
 None
 0.80A 5k4pA-3ohwB:
undetectable		 5k4pA-3ohwB:
17.65