SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oib'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 3oib ACYL-COA
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 GLY A  70
ILE A  93
LEU A  71
ASP A  86
GLY A  85
 None
 1.05A 1jg3A-3oibA:
undetectable		 1jg3A-3oibA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 3oib ACYL-COA
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 GLY A  70
ILE A  93
LEU A  71
ASP A  86
GLY A  85
 None
 1.07A 1jg3B-3oibA:
undetectable		 1jg3B-3oibA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3oib ACYL-COA
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 ARG A 376
GLY A 104
GLU A 370
GLU A 372
SER A 227
 None
 1.41A 1odiA-3oibA:
undetectable		 1odiA-3oibA:
25.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3oib ACYL-COA
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 ARG A 376
GLY A 104
GLU A 370
GLU A 372
SER A 227
 None
 1.41A 1odiE-3oibA:
undetectable		 1odiE-3oibA:
25.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3oib ACYL-COA
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 ARG A 376
GLY A 104
GLU A 370
GLU A 372
SER A 227
 None
 1.43A 1odiF-3oibA:
undetectable		 1odiF-3oibA:
25.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)		 3oib ACYL-COA
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		4 / 6 ALA A 108
LEU A 110
ILE A  58
SER A 181
 None
 1.07A 1sbrA-3oibA:
undetectable
1sbrB-3oibA:
undetectable		 1sbrA-3oibA:
20.20
1sbrB-3oibA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 3oib ACYL-COA
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		4 / 8 LEU A 128
VAL A 246
VAL A 240
ASP A 208
 None
None
None
IOD  A 507 ( 4.1A)
 1.17A 1uyuB-3oibA:
undetectable		 1uyuB-3oibA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BL9_A_CP6A1240_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3oib ACYL-COA
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 MET A  97
SER A 228
SER A 227
ILE A  58
THR A 269
 None
 1.18A 2bl9A-3oibA:
undetectable		 2bl9A-3oibA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 3oib ACYL-COA
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 THR A 251
THR A 190
ALA A 192
SER A 248
GLY A 247
 None
 1.09A 2f162-3oibA:
undetectable		 2f162-3oibA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 3oib ACYL-COA
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 THR A 251
THR A 190
ALA A 192
SER A 248
GLY A 247
 None
 1.10A 2f16N-3oibA:
undetectable		 2f16N-3oibA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A8I_C_C2FC401_0
(AMINOMETHYLTRANSFERA
SE)		 3oib ACYL-COA
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 TYR A 170
ILE A 172
TYR A 235
VAL A 238
THR A 190
 None
 1.43A 3a8iC-3oibA:
undetectable		 3a8iC-3oibA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 3oib ACYL-COA
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 THR A 251
THR A 190
ALA A 192
SER A 248
GLY A 247
 None
 1.11A 3mg0N-3oibA:
undetectable		 3mg0N-3oibA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 3oib ACYL-COA
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 CYH A 113
LEU A  62
GLY A  73
ALA A  66
PHE A 111
 None
IOD  A 502 ( 4.4A)
None
None
None
 1.20A 4n09A-3oibA:
undetectable		 4n09A-3oibA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 3oib ACYL-COA
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		4 / 7 GLU A 350
THR A 388
GLY A 382
THR A 387
 None
None
None
FDA  A 518 (-2.9A)
 0.80A 4qwpB-3oibA:
2.1		 4qwpB-3oibA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_1
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)		 3oib ACYL-COA
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		4 / 4 THR A 180
GLY A 104
ASP A 377
SER A 109
 FDA  A 518 (-3.9A)
None
None
None
 0.92A 4rfqA-3oibA:
undetectable		 4rfqA-3oibA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3oib ACYL-COA
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		4 / 6 ASP A 229
ALA A 185
THR A 180
THR A 112
 None
None
FDA  A 518 (-3.9A)
None
 1.39A 4w5qA-3oibA:
undetectable		 4w5qA-3oibA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3oib ACYL-COA
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		4 / 6 ASP A 229
ALA A 185
THR A 180
THR A 112
 None
None
FDA  A 518 (-3.9A)
None
 1.33A 4w5rA-3oibA:
undetectable		 4w5rA-3oibA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3oib ACYL-COA
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		4 / 6 ASP A 229
ALA A 185
THR A 180
THR A 112
 None
None
FDA  A 518 (-3.9A)
None
 1.36A 4w5tA-3oibA:
undetectable		 4w5tA-3oibA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 3oib ACYL-COA
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		4 / 6 ASP A 229
ALA A 185
THR A 180
THR A 112
 None
None
FDA  A 518 (-3.9A)
None
 1.34A 4z4cA-3oibA:
undetectable		 4z4cA-3oibA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3oib ACYL-COA
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		4 / 6 ASP A 229
ALA A 185
THR A 180
THR A 112
 None
None
FDA  A 518 (-3.9A)
None
 1.36A 4z4fA-3oibA:
undetectable		 4z4fA-3oibA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3oib ACYL-COA
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		4 / 5 ASP A 229
ALA A 185
THR A 180
THR A 112
 None
None
FDA  A 518 (-3.9A)
None
 1.37A 4z4gA-3oibA:
undetectable		 4z4gA-3oibA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3oib ACYL-COA
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		4 / 6 ASP A 229
ALA A 185
THR A 180
THR A 112
 None
None
FDA  A 518 (-3.9A)
None
 1.38A 4z4iA-3oibA:
undetectable		 4z4iA-3oibA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_ACTD305_0
(CARBONIC ANHYDRASE 4)		 3oib ACYL-COA
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		4 / 5 ALA A 192
ALA A 163
ILE A 205
LEU A 245
 None
 0.78A 5jncD-3oibA:
undetectable		 5jncD-3oibA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_D_CCSD14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2
PROGRAMMED CELL
DEATH 1 LIGAND 1)		 3oib ACYL-COA
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A 220
SER A 228
ARG A 184
GLY A 182
VAL A 183
 None
 1.17A 5o4yD-3oibA:
undetectable
5o4yE-3oibA:
undetectable		 5o4yD-3oibA:
3.92
5o4yE-3oibA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNI_A_YMZA302_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3oib ACYL-COA
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 9 VAL A 261
GLY A  75
ASP A  86
GLY A  85
PRO A  77
 IOD  A 512 ( 4.1A)
None
None
None
None
 1.39A 5zniA-3oibA:
undetectable		 5zniA-3oibA:
11.19