SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oid'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO6_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 3oid ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADPH]
(Bacillus
subtilis) 		5 / 12 LEU A 161
LEU A 117
ALA A 181
VAL A 182
THR A  10
 None
 1.08A 2qo6A-3oidA:
undetectable		 2qo6A-3oidA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 3oid ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADPH]
(Bacillus
subtilis) 		4 / 8 LEU A 168
GLU A 123
ALA A 124
ALA A 125
 None
 0.69A 3r9tA-3oidA:
undetectable		 3r9tA-3oidA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_B_BEZB264_0
(ECHA1_1)		 3oid ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADPH]
(Bacillus
subtilis) 		4 / 7 LEU A 168
GLU A 123
ALA A 124
ALA A 125
 None
 0.69A 3r9tB-3oidA:
undetectable		 3r9tB-3oidA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_A_CL6A502_1
(CYTOCHROME P-450)		 3oid ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADPH]
(Bacillus
subtilis) 		4 / 5 LEU A 161
ALA A 121
VAL A  63
ILE A  69
 None
None
NDP  A 501 (-3.7A)
None
 0.93A 4xe3A-3oidA:
undetectable		 4xe3A-3oidA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 3oid ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADPH]
(Bacillus
subtilis) 		3 / 3 GLY A  81
GLN A   3
LYS A 130
 None
 0.87A 5imsB-3oidA:
4.2		 5imsB-3oidA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_0
(CYTOCHROME P450 1A1)		 3oid ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADPH]
(Bacillus
subtilis) 		5 / 12 ILE A 145
SER A 247
LEU A 161
GLY A 184
LEU A 148
 None
None
None
NDP  A 501 (-3.9A)
None
 1.15A 6dwnC-3oidA:
undetectable		 6dwnC-3oidA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 3oid ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADPH]
(Bacillus
subtilis) 		4 / 6 VAL A 154
ASN A 113
ASN A 111
ILE A 112
 None
None
None
NDP  A 501 (-3.6A)
 1.15A 6h7uA-3oidA:
undetectable		 6h7uA-3oidA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA604_0
(SERUM ALBUMIN)		 3oid ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADPH]
(Bacillus
subtilis) 		4 / 8 LEU A 172
ALA A 125
LYS A 126
GLU A 129
 None
 0.59A 6mdqA-3oidA:
undetectable		 6mdqA-3oidA:
15.09