SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oig'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3oig ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]
(Bacillus
subtilis) 		4 / 7 LEU A 234
ILE A 189
ALA A 216
ILE A 212
 None
 0.85A 2xkwA-3oigA:
undetectable		 2xkwA-3oigA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3oig ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]
(Bacillus
subtilis) 		3 / 3 HIS A 254
GLU A 152
ASN A 246
 None
 0.92A 4bupB-3oigA:
undetectable		 4bupB-3oigA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C66_A_H4CA1168_0
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3oig ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]
(Bacillus
subtilis) 		5 / 9 VAL A 186
LEU A 175
LEU A 179
ILE A  91
MET A  13
 None
 1.47A 4c66A-3oigA:
undetectable		 4c66A-3oigA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3oig ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]
(Bacillus
subtilis) 		4 / 8 ASP A  57
ASP A  60
ASP A 229
GLU A   6
 None
 1.04A 4feuD-3oigA:
undetectable		 4feuD-3oigA:
21.55