SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oit'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 3oit OS07G0271500 PROTEIN
(Oryza
sativa) 		4 / 7 ALA A 392
LEU A 394
SER A 250
VAL A 390
 None
 0.85A 1dvxB-3oitA:
undetectable		 1dvxB-3oitA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 3oit OS07G0271500 PROTEIN
(Oryza
sativa) 		4 / 7 LEU A 203
ALA A 201
SER A 351
VAL A 139
 None
 0.93A 1dvxB-3oitA:
undetectable		 1dvxB-3oitA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4H_A_REAA500_1
(NUCLEAR RECEPTOR
ROR-BETA)		 3oit OS07G0271500 PROTEIN
(Oryza
sativa) 		5 / 11 ILE A 248
ALA A  27
VAL A 234
ARG A 195
ALA A 180
 None
 1.25A 1n4hA-3oitA:
undetectable		 1n4hA-3oitA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3oit OS07G0271500 PROTEIN
(Oryza
sativa) 		5 / 10 LEU A 181
LEU A  30
VAL A 196
GLY A 235
ALA A 188
 None
 1.13A 1pxxA-3oitA:
undetectable		 1pxxA-3oitA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_B_DIFB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3oit OS07G0271500 PROTEIN
(Oryza
sativa) 		5 / 9 LEU A 181
LEU A  30
VAL A 196
GLY A 235
ALA A 188
 None
 1.13A 1pxxB-3oitA:
undetectable		 1pxxB-3oitA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_D_DIFD3701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3oit OS07G0271500 PROTEIN
(Oryza
sativa) 		5 / 10 LEU A 181
LEU A  30
VAL A 196
GLY A 235
ALA A 188
 None
 1.13A 1pxxD-3oitA:
undetectable		 1pxxD-3oitA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_B_9CRB130_1
(TRANSTHYRETIN)		 3oit OS07G0271500 PROTEIN
(Oryza
sativa) 		4 / 7 LEU A 203
ALA A 201
SER A 351
VAL A 139
 None
 0.86A 1tyrB-3oitA:
undetectable		 1tyrB-3oitA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3oit OS07G0271500 PROTEIN
(Oryza
sativa) 		5 / 12 THR A 389
GLN A 253
ALA A 179
CYH A 178
VAL A 355
 None
 1.33A 2g72B-3oitA:
undetectable		 2g72B-3oitA:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_1
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 3oit OS07G0271500 PROTEIN
(Oryza
sativa) 		5 / 12 ALA A 180
THR A 140
ALA A 116
ALA A 119
ILE A 356
 None
 1.04A 2nyrA-3oitA:
undetectable		 2nyrA-3oitA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_B_1FLB500_1
(TRANSTHYRETIN)		 3oit OS07G0271500 PROTEIN
(Oryza
sativa) 		4 / 6 ALA A 201
LEU A 203
THR A 141
VAL A 139
 None
 0.77A 3d2tB-3oitA:
undetectable		 3d2tB-3oitA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_B_1FLB500_1
(TRANSTHYRETIN)		 3oit OS07G0271500 PROTEIN
(Oryza
sativa) 		4 / 6 ALA A 392
LEU A 394
SER A 250
VAL A 390
 None
 0.99A 3d2tB-3oitA:
undetectable		 3d2tB-3oitA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 3oit OS07G0271500 PROTEIN
(Oryza
sativa) 		4 / 6 LEU A 101
SER A 100
ARG A 271
LEU A 105
 None
 1.04A 3f33A-3oitA:
undetectable		 3f33A-3oitA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3oit OS07G0271500 PROTEIN
(Oryza
sativa) 		5 / 11 GLY A 352
GLY A 173
ALA A 201
ALA A 230
ALA A 179
 None
 1.11A 3g88A-3oitA:
undetectable		 3g88A-3oitA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3oit OS07G0271500 PROTEIN
(Oryza
sativa) 		5 / 11 GLY A 352
GLY A 173
ALA A 201
ALA A 230
ALA A 179
 None
 1.11A 3g88B-3oitA:
undetectable		 3g88B-3oitA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3oit OS07G0271500 PROTEIN
(Oryza
sativa) 		5 / 12 GLY A 352
GLY A 173
ALA A 201
ALA A 230
ALA A 179
 None
 1.08A 3g8bB-3oitA:
undetectable		 3g8bB-3oitA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_A_T44A128_1
(TRANSTHYRETIN)		 3oit OS07G0271500 PROTEIN
(Oryza
sativa) 		5 / 9 ALA A 201
LEU A 203
SER A 143
THR A 141
VAL A 139
 None
 1.33A 3ozkA-3oitA:
undetectable		 3ozkA-3oitA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAV_A_RAVA183_1
(FERRITIN LIGHT CHAIN)		 3oit OS07G0271500 PROTEIN
(Oryza
sativa) 		4 / 6 LEU A 101
SER A 100
ARG A 271
LEU A 105
 None
 1.06A 3ravA-3oitA:
undetectable		 3ravA-3oitA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3oit OS07G0271500 PROTEIN
(Oryza
sativa) 		3 / 3 SER A 340
ASP A 286
ASP A 327
 None
 0.62A 4uckA-3oitA:
undetectable		 4uckA-3oitA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 3oit OS07G0271500 PROTEIN
(Oryza
sativa) 		4 / 5 PHE A 384
PRO A 317
VAL A 315
ALA A 383
 None
 1.32A 4w5oA-3oitA:
undetectable		 4w5oA-3oitA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3oit OS07G0271500 PROTEIN
(Oryza
sativa) 		4 / 5 PHE A 384
PRO A 317
VAL A 315
ALA A 383
 None
 1.33A 4z4cA-3oitA:
undetectable		 4z4cA-3oitA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3oit OS07G0271500 PROTEIN
(Oryza
sativa) 		4 / 5 PHE A 384
PRO A 317
VAL A 315
ALA A 383
 None
 1.33A 4z4dA-3oitA:
undetectable		 4z4dA-3oitA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 3oit OS07G0271500 PROTEIN
(Oryza
sativa) 		4 / 5 PHE A 384
PRO A 317
VAL A 315
ALA A 383
 None
 1.32A 4z4eA-3oitA:
undetectable		 4z4eA-3oitA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)		 3oit OS07G0271500 PROTEIN
(Oryza
sativa) 		4 / 6 ALA A 392
LEU A 394
SER A 250
VAL A 390
 None
 0.92A 5a6iA-3oitA:
undetectable		 5a6iA-3oitA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_D_ADND502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3oit OS07G0271500 PROTEIN
(Oryza
sativa) 		3 / 3 THR A 204
THR A  54
LEU A 219
 None
 0.68A 5m66D-3oitA:
undetectable		 5m66D-3oitA:
22.36