SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oiz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGL_A_RZXA257_1
(CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1)		 3oiz ANTISIGMA-FACTOR
ANTAGONIST, STAS
(Rhodobacter
sphaeroides) 		4 / 7 PHE A 424
VAL A 408
ILE A 435
SER A 447
 None
 0.96A 3pglA-3oizA:
undetectable		 3pglA-3oizA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3oiz ANTISIGMA-FACTOR
ANTAGONIST, STAS
(Rhodobacter
sphaeroides) 		4 / 8 SER A 474
ILE A 442
TRP A 443
GLU A 475
 None
 1.27A 4cx7A-3oizA:
undetectable
4cx7B-3oizA:
undetectable		 4cx7A-3oizA:
13.26
4cx7B-3oizA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3oiz ANTISIGMA-FACTOR
ANTAGONIST, STAS
(Rhodobacter
sphaeroides) 		5 / 10 ALA A 463
VAL A 465
GLU A 464
ASP A 436
ILE A 435
 None
 1.12A 5i3cB-3oizA:
undetectable		 5i3cB-3oizA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_B_LEVB801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 3oiz ANTISIGMA-FACTOR
ANTAGONIST, STAS
(Rhodobacter
sphaeroides) 		3 / 3 TYR A 406
LEU A 397
ASP A 400
 None
 0.89A 5zv2B-3oizA:
undetectable		 5zv2B-3oizA:
22.12