SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oja'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		4 / 6 LEU B 321
ILE B 350
TYR B 380
VAL B 313
 None
 0.94A 1db1A-3ojaB:
undetectable		 1db1A-3ojaB:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_2
(ESTROGEN RECEPTOR)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		5 / 6 LEU B 466
LEU B 518
HIS B 460
LEU B 420
LEU B 422
 None
 1.49A 1errA-3ojaB:
undetectable		 1errA-3ojaB:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_0
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		4 / 4 THR B 666
LEU B 669
LEU B 676
GLN B 679
 None
 1.25A 1fbmA-3ojaB:
3.5		 1fbmA-3ojaB:
5.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_0
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3oja LEUCINE-RICH IMMUNE
MOLECULE 1
(Anopheles
gambiae) 		4 / 4 THR A 493
LEU A 497
LEU A 504
GLN A 507
 None
 0.62A 1fbmA-3ojaA:
4.2		 1fbmA-3ojaA:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3oja LEUCINE-RICH IMMUNE
MOLECULE 1
(Anopheles
gambiae) 		4 / 5 THR A 493
LEU A 497
LEU A 504
GLN A 507
 None
 0.57A 1fbmE-3ojaA:
4.0		 1fbmE-3ojaA:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_2
(HMG-COA REDUCTASE)		 3oja LEUCINE-RICH IMMUNE
MOLECULE 1
(Anopheles
gambiae) 		4 / 8 ASN A  90
LEU A  44
ALA A  47
LEU A  48
 None
 0.85A 1hwiD-3ojaA:
undetectable		 1hwiD-3ojaA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEH_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 3oja LEUCINE-RICH IMMUNE
MOLECULE 1
(Anopheles
gambiae) 		5 / 10 SER A 221
SER A 222
ASN A 223
GLY A 268
ARG A 267
 None
 1.32A 1mehA-3ojaA:
undetectable		 1mehA-3ojaA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_ACTH611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		4 / 6 LEU B 334
TRP B 376
ASN B 369
LEU B 371
 None
 1.44A 1ru9H-3ojaB:
undetectable
1ru9L-3ojaB:
undetectable		 1ru9H-3ojaB:
16.52
1ru9L-3ojaB:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		4 / 6 LEU B 334
TRP B 376
ASN B 369
LEU B 371
 None
 1.44A 1rukH-3ojaB:
undetectable
1rukL-3ojaB:
undetectable		 1rukH-3ojaB:
16.52
1rukL-3ojaB:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUL_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		4 / 5 LEU B 334
TRP B 376
ASN B 369
LEU B 371
 None
 1.47A 1rulH-3ojaB:
undetectable
1rulL-3ojaB:
undetectable		 1rulH-3ojaB:
16.52
1rulL-3ojaB:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		5 / 12 LEU B 377
PHE B 401
LEU B 393
ILE B 396
ILE B 412
 None
 1.03A 2bxqA-3ojaB:
undetectable		 2bxqA-3ojaB:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_A_SAMA1500_0
(ASPARTOKINASE)		 3oja LEUCINE-RICH IMMUNE
MOLECULE 1
(Anopheles
gambiae) 		4 / 8 ILE A  71
SER A  72
ASP A  75
SER A  43
 None
 0.99A 2cdqA-3ojaA:
undetectable		 2cdqA-3ojaA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)		 3oja LEUCINE-RICH IMMUNE
MOLECULE 1
(Anopheles
gambiae) 		5 / 10 ALA A  47
LEU A  85
LEU A  76
SER A  43
LEU A  44
 None
 1.32A 2ceoB-3ojaA:
undetectable		 2ceoB-3ojaA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1478_1
(NEURAMINIDASE)		 3oja LEUCINE-RICH IMMUNE
MOLECULE 1
(Anopheles
gambiae) 		4 / 7 SER A  88
SER A  89
SER A  64
ASN A  86
 NAG  A1001 ( 4.4A)
None
NAG  A1001 (-3.1A)
NAG  A1001 (-1.8A)
 1.09A 2cmlA-3ojaA:
undetectable		 2cmlA-3ojaA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)		 3oja LEUCINE-RICH IMMUNE
MOLECULE 1
(Anopheles
gambiae) 		4 / 8 SER A  88
SER A  89
SER A  64
ASN A  86
 NAG  A1001 ( 4.4A)
None
NAG  A1001 (-3.1A)
NAG  A1001 (-1.8A)
 0.98A 2cmlB-3ojaA:
undetectable		 2cmlB-3ojaA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)		 3oja LEUCINE-RICH IMMUNE
MOLECULE 1
(Anopheles
gambiae) 		4 / 8 SER A  88
SER A  89
SER A  64
ASN A  86
 NAG  A1001 ( 4.4A)
None
NAG  A1001 (-3.1A)
NAG  A1001 (-1.8A)
 1.07A 2cmlC-3ojaA:
undetectable		 2cmlC-3ojaA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)		 3oja LEUCINE-RICH IMMUNE
MOLECULE 1
(Anopheles
gambiae) 		4 / 8 SER A  88
SER A  89
SER A  64
ASN A  86
 NAG  A1001 ( 4.4A)
None
NAG  A1001 (-3.1A)
NAG  A1001 (-1.8A)
 1.15A 2cmlD-3ojaA:
undetectable		 2cmlD-3ojaA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		4 / 6 LEU B 334
LEU B 331
ILE B 336
ARG B 354
 None
 1.01A 2rlfB-3ojaB:
undetectable
2rlfC-3ojaB:
undetectable		 2rlfB-3ojaB:
5.13
2rlfC-3ojaB:
5.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3oja LEUCINE-RICH IMMUNE
MOLECULE 1
(Anopheles
gambiae) 		4 / 8 ILE A 203
LEU A 173
LEU A 171
PHE A 183
 None
 0.80A 2vctA-3ojaA:
undetectable		 2vctA-3ojaA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3oja LEUCINE-RICH IMMUNE
MOLECULE 1
(Anopheles
gambiae) 		4 / 8 ILE A 203
LEU A 173
LEU A 171
PHE A 183
 None
 0.80A 2vctB-3ojaA:
undetectable		 2vctB-3ojaA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		4 / 8 THR B 478
ASP B 459
SER B 436
TYR B 411
 None
 1.24A 2xz5A-3ojaB:
undetectable
2xz5C-3ojaB:
undetectable		 2xz5A-3ojaB:
16.01
2xz5C-3ojaB:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		4 / 8 THR B 478
ASP B 459
SER B 436
TYR B 411
 None
 1.22A 2xz5C-3ojaB:
undetectable
2xz5D-3ojaB:
undetectable		 2xz5C-3ojaB:
16.01
2xz5D-3ojaB:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_B_CTCB1385_0
(TETX2 PROTEIN)		 3oja LEUCINE-RICH IMMUNE
MOLECULE 1
(Anopheles
gambiae) 		4 / 8 GLN A 209
PHE A 183
GLY A 208
GLY A 237
 None
 0.95A 2y6rB-3ojaA:
undetectable		 2y6rB-3ojaA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		4 / 8 ASN B 391
ASN B 369
ILE B 336
VAL B 386
 None
 0.86A 2yoeB-3ojaB:
undetectable
2yoeC-3ojaB:
undetectable		 2yoeB-3ojaB:
18.96
2yoeC-3ojaB:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		4 / 8 ASN B 391
ARG B 621
ASP B 387
SER B 413
 None
 1.11A 2zw9B-3ojaB:
undetectable		 2zw9B-3ojaB:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_D_VD3D2001_1
(VITAMIN D
HYDROXYLASE)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		5 / 12 MET B 190
ILE B 214
LEU B 212
ALA B 221
LEU B 231
 None
 0.93A 3a50D-3ojaB:
undetectable		 3a50D-3ojaB:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_A_1GNA998_1
(GALECTIN-7)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		4 / 6 ASN B 414
ARG B 621
ASN B 391
GLU B 392
 None
 1.40A 3galA-3ojaB:
undetectable		 3galA-3ojaB:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_B_1GNB999_1
(GALECTIN-7)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		4 / 6 ASN B 414
ARG B 621
ASN B 391
GLU B 392
 None
 1.40A 3galB-3ojaB:
undetectable		 3galB-3ojaB:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I45_A_NIOA500_1
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		4 / 8 PHE B 156
LEU B 207
PHE B 201
LEU B 198
 None
 1.03A 3i45A-3ojaB:
undetectable		 3i45A-3ojaB:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_H_TRUH800_1
(GLUTAMATE RECEPTOR 2)		 3oja LEUCINE-RICH IMMUNE
MOLECULE 1
(Anopheles
gambiae) 		3 / 3 ILE A 123
SER A 139
SER A 137
 None
 0.61A 3iltH-3ojaA:
undetectable		 3iltH-3ojaA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		4 / 7 ARG B 498
SER B 480
LEU B 468
ILE B 463
 None
 0.83A 3ln1C-3ojaB:
undetectable		 3ln1C-3ojaB:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK2_X_LDPX433_1
(6-HYDROXY-L-NICOTINE
OXIDASE)		 3oja LEUCINE-RICH IMMUNE
MOLECULE 1
(Anopheles
gambiae) 		4 / 7 TYR A 316
LEU A 250
LEU A 266
PHE A 280
 None
 1.20A 3nk2X-3ojaA:
undetectable		 3nk2X-3ojaA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_D_T44D328_1
(5-HYDROXYISOURATE
HYDROLASE)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		5 / 9 LEU B 422
PRO B 400
THR B 374
LEU B 388
LEU B 393
 None
 1.30A 3q1eB-3ojaB:
undetectable
3q1eD-3ojaB:
undetectable		 3q1eB-3ojaB:
11.51
3q1eD-3ojaB:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA452_1
(CYTOCHROME P450
164A2)		 3oja LEUCINE-RICH IMMUNE
MOLECULE 1
(Anopheles
gambiae) 		5 / 12 ALA A 184
LEU A 186
LEU A 196
LEU A 198
ASN A 182
 None
 0.81A 3r9cA-3ojaA:
undetectable		 3r9cA-3ojaA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 3oja LEUCINE-RICH IMMUNE
MOLECULE 1
(Anopheles
gambiae) 		4 / 8 GLN A 209
PHE A 183
GLY A 208
GLY A 237
 None
 0.93A 3v3nB-3ojaA:
undetectable		 3v3nB-3ojaA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		5 / 12 ARG B 354
ASN B 348
ASN B 329
LEU B 310
ILE B 289
 None
 1.48A 4kukA-3ojaB:
undetectable		 4kukA-3ojaB:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3oja LEUCINE-RICH IMMUNE
MOLECULE 1
(Anopheles
gambiae) 		4 / 8 LEU A  44
VAL A  39
LEU A  96
LEU A  92
 None
 0.94A 4l1xA-3ojaA:
undetectable		 4l1xA-3ojaA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_C_TMQC202_1
(DIHYDROFOLATE
REDUCTASE)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
LEUCINE-RICH IMMUNE
MOLECULE 1
(Anopheles
gambiae) 		5 / 12 ILE A 419
GLN A 414
LEU B 634
LEU A 412
ILE A 437
 None
 1.06A 4m2xC-3ojaA:
undetectable		 4m2xC-3ojaA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 3oja LEUCINE-RICH IMMUNE
MOLECULE 1
(Anopheles
gambiae) 		4 / 5 LEU A  98
LEU A 109
LEU A  76
ASN A 131
 None
 1.19A 4n09B-3ojaA:
undetectable		 4n09B-3ojaA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		5 / 12 PHE B 450
ILE B 463
LEU B 440
LEU B 410
LEU B 433
 None
 1.38A 4qynB-3ojaB:
undetectable		 4qynB-3ojaB:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA502_1
(PENTALENIC ACID
SYNTHASE)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		5 / 9 VAL B 168
LEU B 209
SER B 188
THR B 189
LEU B 212
 None
 1.29A 4ubsA-3ojaB:
undetectable		 4ubsA-3ojaB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		4 / 7 LEU B 315
ALA B 345
ASN B 348
ILE B 350
 None
 0.86A 4y03A-3ojaB:
undetectable		 4y03A-3ojaB:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		5 / 10 SER B 389
GLN B 449
LEU B 422
SER B 413
LEU B 453
 None
 1.10A 4yiaA-3ojaB:
undetectable		 4yiaA-3ojaB:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YO9_B_ACTB401_0
(3C-LIKE PROTEINASE)		 3oja LEUCINE-RICH IMMUNE
MOLECULE 1
ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae;
Anopheles
gambiae) 		3 / 3 ARG B 656
ASP B 660
TYR A 462
 None
 0.80A 4yo9B-3ojaB:
undetectable		 4yo9B-3ojaB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z7F_A_FOLA201_0
(FOLATE ECF
TRANSPORTER)		 3oja LEUCINE-RICH IMMUNE
MOLECULE 1
(Anopheles
gambiae) 		5 / 12 LEU A  92
SER A  64
ALA A 129
TYR A 148
THR A 125
 None
NAG  A1001 (-3.1A)
None
None
None
 1.48A 4z7fA-3ojaA:
0.0		 4z7fA-3ojaA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
LEUCINE-RICH IMMUNE
MOLECULE 1
(Anopheles
gambiae) 		5 / 10 ASP B 681
LEU B 680
LEU A 487
ALA A 483
LEU B 690
 None
 1.13A 4zbrA-3ojaB:
undetectable		 4zbrA-3ojaB:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE0_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		5 / 9 THR B 293
PHE B 294
ILE B 289
PHE B 270
LEU B 241
 None
 1.20A 4ze0A-3ojaB:
undetectable		 4ze0A-3ojaB:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZOW_A_CLMA500_0
(MULTIDRUG
TRANSPORTER MDFA)		 3oja LEUCINE-RICH IMMUNE
MOLECULE 1
(Anopheles
gambiae) 		5 / 11 LEU A 117
LEU A  63
LEU A  82
LEU A 104
LEU A  61
 None
 1.00A 4zowA-3ojaA:
undetectable		 4zowA-3ojaA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3oja LEUCINE-RICH IMMUNE
MOLECULE 1
(Anopheles
gambiae) 		4 / 6 PHE A  79
VAL A  58
TYR A  34
ILE A  27
 None
 1.23A 5iwuA-3ojaA:
undetectable		 5iwuA-3ojaA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_A_ADNA401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3oja LEUCINE-RICH IMMUNE
MOLECULE 1
(Anopheles
gambiae) 		4 / 7 GLU A 252
LYS A 253
ALA A 254
ASP A 278
 None
 0.42A 5mvsA-3ojaA:
2.2		 5mvsA-3ojaA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_B_ADNB401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3oja LEUCINE-RICH IMMUNE
MOLECULE 1
(Anopheles
gambiae) 		4 / 8 GLU A 252
LYS A 253
ALA A 254
ASP A 278
 None
 0.74A 5mvsB-3ojaA:
undetectable		 5mvsB-3ojaA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N1T_W_CUW201_0
(COPC)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		3 / 3 HIS B 437
ASP B 459
HIS B 460
 None
 0.93A 5n1tW-3ojaB:
undetectable		 5n1tW-3ojaB:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_B_SAMB501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		5 / 12 LEU B 257
ILE B 238
LEU B 231
ASN B 210
LEU B 209
 None
 1.05A 5nfjB-3ojaB:
undetectable		 5nfjB-3ojaB:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_C_SAMC501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		5 / 12 LEU B 257
ILE B 238
LEU B 231
ASN B 210
LEU B 209
 None
 1.02A 5nfjC-3ojaB:
undetectable		 5nfjC-3ojaB:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V1T_A_SAMA605_0
(RADICAL SAM)		 3oja LEUCINE-RICH IMMUNE
MOLECULE 1
(Anopheles
gambiae) 		5 / 12 LEU A 198
VAL A 206
VAL A 210
SER A 189
GLU A 185
 None
 1.50A 5v1tA-3ojaA:
undetectable		 5v1tA-3ojaA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AF6_A_GLYA507_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		3 / 3 TYR B 143
HIS B 160
MET B 190
 None
 1.18A 6af6A-3ojaB:
undetectable		 6af6A-3ojaB:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AN0_A_HISA520_0
(HISTIDINOL
DEHYDROGENASE)		 3oja LEUCINE-RICH IMMUNE
MOLECULE 1
ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae;
Anopheles
gambiae) 		4 / 6 GLU B 705
LYS B 700
ARG A 500
GLU A 501
 None
 1.20A 6an0A-3ojaB:
undetectable		 6an0A-3ojaB:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		5 / 12 ILE B 217
LEU B 197
LEU B 241
PHE B 222
LEU B 262
 None
 1.19A 6b54A-3ojaB:
undetectable		 6b54A-3ojaB:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		 3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1
(Anopheles
gambiae) 		4 / 7 ARG B 621
ASN B 391
GLU B 392
ARG B 416
 None
 1.26A 6b8kA-3ojaB:
undetectable		 6b8kA-3ojaB:
8.69