SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ojb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3ojb GALECTIN-8
(Homo
sapiens) 		4 / 7 PHE A  91
PHE A  85
PHE A  63
VAL A  27
 None
 0.90A 1lh6A-3ojbA:
undetectable		 1lh6A-3ojbA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_D_FUAD705_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3ojb GALECTIN-8
(Homo
sapiens) 		5 / 12 SER A 111
PHE A  63
LEU A  58
VAL A  31
PHE A  38
 None
 1.50A 1q23D-3ojbA:
undetectable
1q23E-3ojbA:
undetectable		 1q23D-3ojbA:
19.20
1q23E-3ojbA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3ojb GALECTIN-8
(Homo
sapiens) 		5 / 10 SER A 111
PHE A  63
LEU A  58
VAL A  31
PHE A  38
 None
 1.43A 1q23E-3ojbA:
undetectable		 1q23E-3ojbA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3ojb GALECTIN-8
(Homo
sapiens) 		4 / 5 PHE A  91
PHE A  85
PHE A  63
VAL A  27
 None
 0.88A 2lh6A-3ojbA:
undetectable		 2lh6A-3ojbA:
22.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GAL_A_1GNA998_1
(GALECTIN-7)		 3ojb GALECTIN-8
(Homo
sapiens) 		4 / 6 HIS A  53
ASN A  55
ASN A  66
GLU A  76
 None
 0.82A 3galA-3ojbA:
22.7		 3galA-3ojbA:
35.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GAL_A_1GNA998_1
(GALECTIN-7)		 3ojb GALECTIN-8
(Homo
sapiens) 		4 / 6 HIS A  53
ASN A  55
ASN A  66
TRP A  73
 None
 0.40A 3galA-3ojbA:
22.7		 3galA-3ojbA:
35.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GAL_B_1GNB999_1
(GALECTIN-7)		 3ojb GALECTIN-8
(Homo
sapiens) 		4 / 6 HIS A  53
ASN A  55
ASN A  66
GLU A  76
 None
 0.81A 3galB-3ojbA:
22.5		 3galB-3ojbA:
35.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GAL_B_1GNB999_1
(GALECTIN-7)		 3ojb GALECTIN-8
(Homo
sapiens) 		4 / 6 HIS A  53
ASN A  55
ASN A  66
TRP A  73
 None
 0.40A 3galB-3ojbA:
22.5		 3galB-3ojbA:
35.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IX9_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 3ojb GALECTIN-8
(Homo
sapiens) 		5 / 12 ILE A 129
ALA A  13
LEU A  15
LYS A  28
VAL A  40
 None
 1.13A 3ix9A-3ojbA:
undetectable		 3ix9A-3ojbA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IX9_B_MTXB200_1
(DIHYDROFOLATE
REDUCTASE)		 3ojb GALECTIN-8
(Homo
sapiens) 		5 / 12 ILE A 129
ALA A  13
LEU A  15
LYS A  28
VAL A  40
 None
 1.08A 3ix9B-3ojbA:
undetectable		 3ix9B-3ojbA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_H_P77H203_1
(PROTEIN S100-A4)		 3ojb GALECTIN-8
(Homo
sapiens) 		5 / 10 LEU A  42
ASP A  41
ILE A  95
PHE A  63
SER A  37
 None
 1.49A 3m0wE-3ojbA:
undetectable
3m0wF-3ojbA:
undetectable
3m0wG-3ojbA:
undetectable
3m0wH-3ojbA:
undetectable		 3m0wE-3ojbA:
19.86
3m0wF-3ojbA:
19.86
3m0wG-3ojbA:
19.86
3m0wH-3ojbA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)		 3ojb GALECTIN-8
(Homo
sapiens) 		4 / 8 SER A  37
ARG A  57
ASN A  55
PHE A  38
 None
 1.32A 3n62A-3ojbA:
undetectable		 3n62A-3ojbA:
15.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B8K_A_W9TA300_0
(GALECTIN-3)		 3ojb GALECTIN-8
(Homo
sapiens) 		5 / 7 HIS A  53
ASN A  55
ASN A  66
GLU A  76
ARG A  78
 None
 0.86A 6b8kA-3ojbA:
22.3		 6b8kA-3ojbA:
32.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B8K_A_W9TA300_0
(GALECTIN-3)		 3ojb GALECTIN-8
(Homo
sapiens) 		5 / 7 HIS A  53
ASN A  55
ASN A  66
TRP A  73
ARG A  78
 None
 0.49A 6b8kA-3ojbA:
22.3		 6b8kA-3ojbA:
32.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_A_W9TA201_0
(GALECTIN-1)		 3ojb GALECTIN-8
(Homo
sapiens) 		5 / 8 HIS A  53
ASN A  55
ASN A  66
TRP A  73
ARG A  78
 None
 0.48A 6b94A-3ojbA:
19.7		 6b94A-3ojbA:
36.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_B_W9TB201_0
(GALECTIN-1)		 3ojb GALECTIN-8
(Homo
sapiens) 		5 / 10 HIS A  53
ASN A  55
ASN A  66
TRP A  73
ARG A  78
 None
 0.47A 6b94A-3ojbA:
19.7
6b94B-3ojbA:
19.0		 6b94A-3ojbA:
36.67
6b94B-3ojbA:
36.67