SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ojc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_B_RBFB502_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3ojc PUTATIVE
ASPARTATE/GLUTAMATE
RACEMASE
(Yersinia
pestis) 		5 / 11 ILE A  49
HIS A  88
GLY A  10
SER A  43
LEU A  41
 None
 1.49A 1kyvA-3ojcA:
5.6
1kyvB-3ojcA:
5.6		 1kyvA-3ojcA:
23.55
1kyvB-3ojcA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB6_0
(FERROCHELATASE)		 3ojc PUTATIVE
ASPARTATE/GLUTAMATE
RACEMASE
(Yersinia
pestis) 		5 / 12 MET A 130
LEU A 186
ILE A 161
VAL A 212
VAL A 205
 None
 1.22A 3aqiB-3ojcA:
5.0		 3aqiB-3ojcA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_A_SALA257_1
(TRANSCRIPTIONAL
REGULATOR)		 3ojc PUTATIVE
ASPARTATE/GLUTAMATE
RACEMASE
(Yersinia
pestis) 		4 / 8 SER A  12
CYH A 198
ILE A 162
THR A 126
 None
CA  A 232 (-3.7A)
None
CA  A 232 (-3.6A)
 0.95A 3bpxA-3ojcA:
undetectable
3bpxB-3ojcA:
undetectable		 3bpxA-3ojcA:
22.47
3bpxB-3ojcA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 3ojc PUTATIVE
ASPARTATE/GLUTAMATE
RACEMASE
(Yersinia
pestis) 		4 / 8 GLU A  50
GLN A  53
MET A 130
THR A 129
 None
None
None
CA  A 232 (-3.2A)
 1.13A 4lnwA-3ojcA:
undetectable		 4lnwA-3ojcA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_E_ADNE401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 3ojc PUTATIVE
ASPARTATE/GLUTAMATE
RACEMASE
(Yersinia
pestis) 		5 / 10 GLY A 133
ALA A 106
ILE A 195
VAL A 147
LEU A 123
 None
 0.85A 5lw1E-3ojcA:
undetectable		 5lw1E-3ojcA:
16.37