SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ojl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_1
(CYTOCHROME P450 2C8)		 3ojl CAP5O
(Staphylococcus
aureus) 		5 / 12 SER A 324
THR A 295
VAL A 309
ALA A 343
VAL A 348
 None
 0.92A 2nniA-3ojlA:
undetectable		 2nniA-3ojlA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 3ojl CAP5O
(Staphylococcus
aureus) 		5 / 12 ILE A  78
LEU A 101
MET A 125
ILE A 133
VAL A 183
 None
 1.06A 2ygnA-3ojlA:
undetectable		 2ygnA-3ojlA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)		 3ojl CAP5O
(Staphylococcus
aureus) 		5 / 9 LEU A 162
GLU A 117
VAL A   5
ILE A  17
LEU A  64
 None
 1.19A 3jw3B-3ojlA:
undetectable		 3jw3B-3ojlA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 3ojl CAP5O
(Staphylococcus
aureus) 		4 / 8 ILE A 329
VAL A 291
THR A 395
ILE A 369
 None
 0.87A 3p4wC-3ojlA:
undetectable		 3p4wC-3ojlA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3ojl CAP5O
(Staphylococcus
aureus) 		4 / 8 GLY A 171
VAL A 147
HIS A 148
ILE A 168
 None
 0.93A 4fglD-3ojlA:
4.8		 4fglD-3ojlA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_A_SAMA401_0
(METHYLTRANSFERASE
MPPJ)		 3ojl CAP5O
(Staphylococcus
aureus) 		5 / 12 GLY A   7
GLY A   9
ILE A  31
ALA A 100
ARG A  99
 NAD  A 500 (-3.0A)
NAD  A 500 (-3.0A)
NAD  A 500 (-3.8A)
NAD  A 500 ( 4.1A)
None
 1.19A 4kicA-3ojlA:
5.0		 4kicA-3ojlA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3ojl CAP5O
(Staphylococcus
aureus) 		4 / 6 ASP A 262
ALA A 121
THR A 119
THR A  82
 None
None
NAD  A 500 (-3.7A)
NAD  A 500 (-3.1A)
 1.25A 4w5qA-3ojlA:
undetectable		 4w5qA-3ojlA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3ojl CAP5O
(Staphylococcus
aureus) 		4 / 6 ASP A 262
ALA A 121
THR A 119
THR A  82
 None
None
NAD  A 500 (-3.7A)
NAD  A 500 (-3.1A)
 1.29A 4w5rA-3ojlA:
undetectable		 4w5rA-3ojlA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3ojl CAP5O
(Staphylococcus
aureus) 		4 / 6 ASP A 262
ALA A 121
THR A 119
THR A  82
 None
None
NAD  A 500 (-3.7A)
NAD  A 500 (-3.1A)
 1.23A 4w5tA-3ojlA:
undetectable		 4w5tA-3ojlA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3ojl CAP5O
(Staphylococcus
aureus) 		5 / 12 VAL A 147
LEU A   8
ALA A  79
THR A 113
ALA A 100
 None
None
None
None
NAD  A 500 ( 4.1A)
 1.26A 4x1kA-3ojlA:
3.8
4x1kB-3ojlA:
undetectable		 4x1kA-3ojlA:
22.95
4x1kB-3ojlA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 3ojl CAP5O
(Staphylococcus
aureus) 		4 / 6 ASP A 262
ALA A 121
THR A 119
THR A  82
 None
None
NAD  A 500 (-3.7A)
NAD  A 500 (-3.1A)
 1.24A 4z4cA-3ojlA:
undetectable		 4z4cA-3ojlA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3ojl CAP5O
(Staphylococcus
aureus) 		4 / 6 ASP A 262
ALA A 121
THR A 119
THR A  82
 None
None
NAD  A 500 (-3.7A)
NAD  A 500 (-3.1A)
 1.26A 4z4fA-3ojlA:
undetectable		 4z4fA-3ojlA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3ojl CAP5O
(Staphylococcus
aureus) 		4 / 5 ASP A 262
ALA A 121
THR A 119
THR A  82
 None
None
NAD  A 500 (-3.7A)
NAD  A 500 (-3.1A)
 1.26A 4z4gA-3ojlA:
2.4		 4z4gA-3ojlA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3ojl CAP5O
(Staphylococcus
aureus) 		4 / 6 ASP A 262
ALA A 121
THR A 119
THR A  82
 None
None
NAD  A 500 (-3.7A)
NAD  A 500 (-3.1A)
 1.26A 4z4iA-3ojlA:
undetectable		 4z4iA-3ojlA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 3ojl CAP5O
(Staphylococcus
aureus) 		4 / 5 GLY A 141
PRO A 131
THR A 139
THR A 173
 None
 1.20A 5h5fA-3ojlA:
undetectable		 5h5fA-3ojlA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 3ojl CAP5O
(Staphylococcus
aureus) 		5 / 11 ASP A 126
VAL A  97
ILE A  94
ILE A 144
ILE A 140
 None
 1.04A 5hw8A-3ojlA:
undetectable
5hw8D-3ojlA:
undetectable		 5hw8A-3ojlA:
15.22
5hw8D-3ojlA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_1
(CDL2.3A)		 3ojl CAP5O
(Staphylococcus
aureus) 		5 / 12 LEU A 379
PHE A 376
LEU A 312
THR A 308
ALA A 360
 None
 1.21A 5ieoA-3ojlA:
undetectable		 5ieoA-3ojlA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)		 3ojl CAP5O
(Staphylococcus
aureus) 		5 / 12 LEU A 379
PHE A 376
LEU A 312
THR A 308
ALA A 360
 None
 1.19A 5iepA-3ojlA:
0.7		 5iepA-3ojlA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 3ojl CAP5O
(Staphylococcus
aureus) 		5 / 9 LEU A 379
PHE A 384
ASP A 381
VAL A 367
ILE A 369
 None
 1.10A 5om2A-3ojlA:
undetectable
5om2B-3ojlA:
undetectable		 5om2A-3ojlA:
13.05
5om2B-3ojlA:
8.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OS7_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3ojl CAP5O
(Staphylococcus
aureus) 		3 / 3 HIS A 359
SER A 358
LYS A 386
 None
 1.32A 5os7A-3ojlA:
undetectable		 5os7A-3ojlA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WY0_A_SAMA800_0
(SMALL RNA
2'-O-METHYLTRANSFERA
SE)		 3ojl CAP5O
(Staphylococcus
aureus) 		5 / 12 GLY A   7
ASP A  30
ILE A  31
ASN A  32
ILE A  11
 NAD  A 500 (-3.0A)
NAD  A 500 (-2.7A)
NAD  A 500 (-3.8A)
None
NAD  A 500 (-4.0A)
 0.51A 5wy0A-3ojlA:
4.4		 5wy0A-3ojlA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXL_A_SAMA401_0
(2-(3-AMINO-3-CARBOXY
PROPYL)HISTIDINE
SYNTHASE)		 3ojl CAP5O
(Staphylococcus
aureus) 		5 / 12 GLY A  12
SER A  73
LYS A   2
VAL A  29
ASP A  30
 None
None
None
None
NAD  A 500 (-2.7A)
 1.50A 6bxlA-3ojlA:
2.8		 6bxlA-3ojlA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 3ojl CAP5O
(Staphylococcus
aureus) 		5 / 12 MET A 192
ILE A 169
GLU A 207
SER A 203
GLU A 201
 None
 1.20A 6bzoC-3ojlA:
undetectable		 6bzoC-3ojlA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3ojl CAP5O
(Staphylococcus
aureus) 		5 / 9 LEU A 221
THR A 222
GLY A 251
ILE A 215
ILE A 236
 None
 1.11A 6ebpA-3ojlA:
undetectable		 6ebpA-3ojlA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3ojl CAP5O
(Staphylococcus
aureus) 		5 / 10 LEU A 221
THR A 222
GLY A 251
ILE A 215
ILE A 236
 None
 1.10A 6ebpB-3ojlA:
undetectable		 6ebpB-3ojlA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3ojl CAP5O
(Staphylococcus
aureus) 		5 / 10 LEU A 221
THR A 222
GLY A 251
ILE A 215
ILE A 236
 None
 1.10A 6ebpC-3ojlA:
undetectable		 6ebpC-3ojlA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3ojl CAP5O
(Staphylococcus
aureus) 		5 / 10 LEU A 221
THR A 222
GLY A 251
ILE A 215
ILE A 236
 None
 1.11A 6ebpD-3ojlA:
undetectable		 6ebpD-3ojlA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3ojl CAP5O
(Staphylococcus
aureus) 		5 / 10 LEU A 221
THR A 222
GLY A 251
ILE A 247
ILE A 236
 None
 0.98A 6ebpD-3ojlA:
undetectable		 6ebpD-3ojlA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3ojl CAP5O
(Staphylococcus
aureus) 		5 / 11 LEU A 221
THR A 222
GLY A 251
ILE A 215
ILE A 236
 None
 1.08A 6ebzA-3ojlA:
undetectable		 6ebzA-3ojlA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3ojl CAP5O
(Staphylococcus
aureus) 		5 / 11 LEU A 221
THR A 222
GLY A 251
ILE A 247
ILE A 236
 None
 0.98A 6ebzA-3ojlA:
undetectable		 6ebzA-3ojlA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3ojl CAP5O
(Staphylococcus
aureus) 		5 / 11 LEU A 221
THR A 222
GLY A 251
ILE A 247
ILE A 236
 None
 1.01A 6ebzB-3ojlA:
undetectable		 6ebzB-3ojlA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3ojl CAP5O
(Staphylococcus
aureus) 		5 / 11 LEU A 221
THR A 222
GLY A 251
ILE A 247
ILE A 236
 None
 1.00A 6ebzC-3ojlA:
undetectable		 6ebzC-3ojlA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3ojl CAP5O
(Staphylococcus
aureus) 		5 / 11 LEU A 368
THR A 308
SER A 365
ILE A 298
ILE A 299
 None
 0.92A 6ebzC-3ojlA:
undetectable		 6ebzC-3ojlA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3ojl CAP5O
(Staphylococcus
aureus) 		5 / 11 LEU A 221
THR A 222
GLY A 251
ILE A 247
ILE A 236
 None
 0.96A 6ebzD-3ojlA:
undetectable		 6ebzD-3ojlA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GMD_B_ACTB402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3ojl CAP5O
(Staphylococcus
aureus) 		3 / 3 HIS A 359
SER A 358
LYS A 386
 None
 1.32A 6gmdB-3ojlA:
undetectable		 6gmdB-3ojlA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 3ojl CAP5O
(Staphylococcus
aureus) 		5 / 11 LEU A 221
THR A 222
GLY A 251
ILE A 247
ILE A 236
 None
 0.96A 6gp2A-3ojlA:
undetectable		 6gp2A-3ojlA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_B_ACTB207_0
(DUF1778
DOMAIN-CONTAINING
PROTEIN
N-ACETYLTRANSFERASE)		 3ojl CAP5O
(Staphylococcus
aureus) 		4 / 6 LEU A 259
CYH A 258
ARG A 211
ARG A 152
 None
NAD  A 500 (-3.5A)
None
None
 1.30A 6gtqB-3ojlA:
undetectable
6gtqD-3ojlA:
undetectable		 6gtqB-3ojlA:
17.40
6gtqD-3ojlA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA605_0
(SERUM ALBUMIN)		 3ojl CAP5O
(Staphylococcus
aureus) 		4 / 8 LYS A 181
GLY A 180
GLY A 170
GLU A 117
 None
 0.88A 6mdqA-3ojlA:
undetectable		 6mdqA-3ojlA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA605_0
(SERUM ALBUMIN)		 3ojl CAP5O
(Staphylococcus
aureus) 		4 / 8 LYS A 181
GLY A 180
GLY A 171
GLU A 117
 None
 0.87A 6mdqA-3ojlA:
undetectable		 6mdqA-3ojlA:
11.24