SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ojy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)
3ojy COMPLEMENT COMPONENT
C8 ALPHA CHAIN
COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo
sapiens)
4 / 7 ASP B 113
TRP B 116
TYR B 404
ARG A 156
None
1.34A 1cebA-3ojyB:
undetectable
1cebA-3ojyB:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_A_DESA129_1
(TRANSTHYRETIN)
3ojy COMPLEMENT COMPONENT
C8 ALPHA CHAIN

(Homo
sapiens)
4 / 4 LYS A 211
LEU A 207
LEU A 246
SER A 244
None
1.36A 1tt6A-3ojyA:
undetectable
1tt6A-3ojyA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_1
(AMINOMETHYLTRANSFERA
SE)
3ojy COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo
sapiens)
3 / 3 ASP B 244
GLU B 192
TYR B 224
None
0.80A 1wsvA-3ojyB:
undetectable
1wsvA-3ojyB:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_1
(AMINOMETHYLTRANSFERA
SE)
3ojy COMPLEMENT COMPONENT
C8 ALPHA CHAIN
COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo
sapiens;
Homo
sapiens)
4 / 4 ASP A  90
GLU A 108
ARG A 177
TYR B 261
CA  A 555 (-3.4A)
None
None
None
1.29A 1wsvB-3ojyA:
0.0
1wsvB-3ojyA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6002_0
(PANTOTHENATE KINASE)
3ojy COMPLEMENT COMPONENT
C8 ALPHA CHAIN

(Homo
sapiens)
4 / 8 THR A 410
GLY A 375
ARG A 381
ILE A 389
None
0.83A 2f9wA-3ojyA:
undetectable
2f9wB-3ojyA:
undetectable
2f9wA-3ojyA:
18.75
2f9wB-3ojyA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q2H_B_ACTB501_0
(SECRETION CHAPERONE,
PHAGE-DISPLAY
DERIVED PEPTIDE)
3ojy COMPLEMENT COMPONENT
C8 ALPHA CHAIN

(Homo
sapiens)
3 / 3 ARG A 261
SER A 196
TYR A 200
None
0.93A 2q2hA-3ojyA:
undetectable
2q2hB-3ojyA:
undetectable
2q2hA-3ojyA:
13.00
2q2hB-3ojyA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)
3ojy COMPLEMENT COMPONENT
C8 ALPHA CHAIN
COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo
sapiens;
Homo
sapiens)
3 / 3 GLN B 114
THR B 154
TRP A 155
None
1.09A 2rctA-3ojyB:
undetectable
2rctA-3ojyB:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM8_A_ACAA511_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)
3ojy COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo
sapiens)
4 / 8 TYR B 250
ILE B 118
TYR B 115
HIS B 149
None
0.97A 2zm8A-3ojyB:
undetectable
2zm8A-3ojyB:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)
3ojy COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo
sapiens)
4 / 8 TYR B 250
ILE B 118
TYR B 115
HIS B 149
None
0.99A 2zmaA-3ojyB:
undetectable
2zmaA-3ojyB:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_1
(PROTEASE)
3ojy COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo
sapiens)
5 / 10 LEU B 121
VAL B 413
ILE B 214
ALA B 294
ILE B 291
None
0.99A 3ekpC-3ojyB:
undetectable
3ekpC-3ojyB:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)
3ojy COMPLEMENT COMPONENT
C8 ALPHA CHAIN
COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo
sapiens)
5 / 12 VAL B 473
ILE A 195
ILE B 381
VAL B 373
TYR B 300
None
1.28A 3g8iA-3ojyB:
undetectable
3g8iA-3ojyB:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)
3ojy COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo
sapiens)
4 / 7 VAL B 136
ILE B 291
TYR B 290
ILE B 125
None
0.85A 3hgxA-3ojyB:
undetectable
3hgxA-3ojyB:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I45_A_NIOA500_1
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN)
3ojy COMPLEMENT COMPONENT
C8 ALPHA CHAIN

(Homo
sapiens)
5 / 8 LEU A 461
TYR A 297
TYR A 460
PHE A 464
LEU A 129
None
1.44A 3i45A-3ojyA:
undetectable
3i45A-3ojyA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)
3ojy COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo
sapiens)
3 / 3 SER B 232
ASP B 491
ASN B 515
None
0.87A 3lsfB-3ojyB:
undetectable
3lsfE-3ojyB:
undetectable
3lsfB-3ojyB:
19.72
3lsfE-3ojyB:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)
3ojy COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo
sapiens)
3 / 3 ASP B 491
ASN B 515
SER B 232
None
0.82A 3lsfB-3ojyB:
undetectable
3lsfE-3ojyB:
undetectable
3lsfB-3ojyB:
19.72
3lsfE-3ojyB:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA802_0
(GLUTAMATE RECEPTOR 2)
3ojy COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo
sapiens)
3 / 3 ASP B 491
ASN B 515
SER B 232
None
0.89A 3lslA-3ojyB:
undetectable
3lslD-3ojyB:
undetectable
3lslA-3ojyB:
19.53
3lslD-3ojyB:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)
3ojy COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo
sapiens)
3 / 3 SER B 232
ASP B 491
ASN B 515
None
0.80A 3lslA-3ojyB:
undetectable
3lslD-3ojyB:
undetectable
3lslA-3ojyB:
19.53
3lslD-3ojyB:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ0_X_DXCX75_0
(CYTOCHROME C7)
3ojy COMPLEMENT COMPONENT
C8 ALPHA CHAIN

(Homo
sapiens)
4 / 7 ILE A 337
PHE A 372
LYS A 376
GLY A 375
None
1.24A 3sj0X-3ojyA:
undetectable
3sj0X-3ojyA:
8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)
3ojy COMPLEMENT COMPONENT
C8 ALPHA CHAIN

(Homo
sapiens)
3 / 3 PRO A  36
THR A 483
LEU A  11
None
0.75A 3ttrA-3ojyA:
undetectable
3ttrA-3ojyA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)
3ojy COMPLEMENT COMPONENT
C8 ALPHA CHAIN

(Homo
sapiens)
4 / 7 ASP A  96
GLU A 282
ASP A  88
GLU A  97
CA  A 555 (-3.2A)
None
None
CA  A 555 (-3.2A)
1.22A 4fevD-3ojyA:
undetectable
4fevD-3ojyA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)
3ojy COMPLEMENT COMPONENT
C8 ALPHA CHAIN

(Homo
sapiens)
4 / 7 ASP A  96
GLU A 282
ASP A  88
GLU A  97
CA  A 555 (-3.2A)
None
None
CA  A 555 (-3.2A)
1.23A 4fexB-3ojyA:
undetectable
4fexB-3ojyA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_1
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)
3ojy COMPLEMENT COMPONENT
C8 ALPHA CHAIN
COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo
sapiens;
Homo
sapiens)
3 / 3 GLU B  98
ASP B  89
ASP A 107
CA  B 538 (-3.0A)
None
None
0.77A 4gc9A-3ojyB:
undetectable
4gc9A-3ojyB:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)
3ojy COMPLEMENT COMPONENT
C8 ALPHA CHAIN

(Homo
sapiens)
4 / 8 ASP A  96
GLU A 282
ASP A  88
GLU A  97
CA  A 555 (-3.2A)
None
None
CA  A 555 (-3.2A)
1.21A 4gkhB-3ojyA:
undetectable
4gkhB-3ojyA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)
3ojy COMPLEMENT COMPONENT
C8 ALPHA CHAIN

(Homo
sapiens)
4 / 7 ASP A  96
GLU A 282
ASP A  88
GLU A  97
CA  A 555 (-3.2A)
None
None
CA  A 555 (-3.2A)
1.22A 4gkhG-3ojyA:
undetectable
4gkhG-3ojyA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)
3ojy COMPLEMENT COMPONENT
C8 ALPHA CHAIN

(Homo
sapiens)
4 / 8 ASP A  96
GLU A 282
ASP A  88
GLU A  97
CA  A 555 (-3.2A)
None
None
CA  A 555 (-3.2A)
1.18A 4gkiC-3ojyA:
undetectable
4gkiC-3ojyA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_1
(NEURAMINIDASE)
3ojy COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo
sapiens)
3 / 3 ARG B  82
GLU B  69
ARG B  83
None
0.78A 4mwvA-3ojyB:
undetectable
4mwvA-3ojyB:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_1
(NEURAMINIDASE)
3ojy COMPLEMENT COMPONENT
C8 ALPHA CHAIN
COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo
sapiens;
Homo
sapiens)
3 / 3 ARG B 102
ASP A 102
ARG B 103
None
0.97A 4mx0A-3ojyB:
undetectable
4mx0A-3ojyB:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)
3ojy COMPLEMENT COMPONENT
C8 ALPHA CHAIN

(Homo
sapiens)
5 / 11 LEU A 350
ILE A 389
LEU A 325
ILE A 411
PHE A 346
None
1.01A 4odrA-3ojyA:
undetectable
4odrB-3ojyA:
undetectable
4odrA-3ojyA:
10.69
4odrB-3ojyA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_G_377G401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
3ojy COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo
sapiens)
4 / 6 TYR B  30
ARG B 269
TYR B 279
LEU B 282
None
1.27A 4twdF-3ojyB:
undetectable
4twdG-3ojyB:
undetectable
4twdF-3ojyB:
18.95
4twdG-3ojyB:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_0
(PROLINE--TRNA LIGASE)
3ojy COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo
sapiens)
5 / 12 PHE B 210
GLU B 192
GLU B 246
HIS B 249
GLY B 297
None
1.13A 4ydqB-3ojyB:
undetectable
4ydqB-3ojyB:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_A_ACTA403_0
(D-ALANINE--D-ALANINE
LIGASE)
3ojy COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo
sapiens)
4 / 6 TYR B 165
GLY B 119
SER B 120
LEU B 121
None
1.23A 5bphA-3ojyB:
undetectable
5bphA-3ojyB:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)
3ojy COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo
sapiens)
4 / 4 TYR B 165
GLY B 119
SER B 120
LEU B 121
None
1.25A 5bphC-3ojyB:
undetectable
5bphC-3ojyB:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Z_BEZZ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)
3ojy COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo
sapiens)
4 / 4 ILE B 409
GLY B 213
ILE B 299
LEU B 212
None
0.88A 5dzkl-3ojyB:
undetectable
5dzkz-3ojyB:
undetectable
5dzkl-3ojyB:
17.97
5dzkz-3ojyB:
5.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_J_BEZJ1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)
3ojy COMPLEMENT COMPONENT
C8 ALPHA CHAIN

(Homo
sapiens)
3 / 3 SER A 141
TYR A 142
TYR A 143
None
0.90A 5lakC-3ojyA:
undetectable
5lakJ-3ojyA:
undetectable
5lakC-3ojyA:
18.77
5lakJ-3ojyA:
3.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)
3ojy COMPLEMENT COMPONENT
C8 ALPHA CHAIN

(Homo
sapiens)
4 / 5 LEU A 446
LEU A 438
MET A 279
GLN A  65
None
1.34A 5uc3A-3ojyA:
undetectable
5uc3A-3ojyA:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_2
(CYTOCHROME P450 3A4)
3ojy COMPLEMENT COMPONENT
C8 ALPHA CHAIN

(Homo
sapiens)
4 / 6 ARG A 392
PHE A 259
ILE A 342
THR A 343
None
0.90A 5vceA-3ojyA:
undetectable
5vceA-3ojyA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_1
(REGULATORY PROTEIN
TETR)
3ojy COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo
sapiens)
4 / 8 GLY B 297
ARG B 242
TRP B 398
ASP B 244
None
0.59A 5vlmA-3ojyB:
undetectable
5vlmA-3ojyB:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_1
(REGULATORY PROTEIN
TETR)
3ojy COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo
sapiens)
4 / 8 GLY B 297
ARG B 242
TRP B 398
ASP B 244
None
0.86A 5vlmB-3ojyB:
undetectable
5vlmB-3ojyB:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_1
(REGULATORY PROTEIN
TETR)
3ojy COMPLEMENT COMPONENT
C8 ALPHA CHAIN
COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo
sapiens;
Homo
sapiens)
4 / 7 GLY A 318
TYR A 126
ASP A 428
ASP B 219
None
1.15A 5vlmE-3ojyA:
undetectable
5vlmE-3ojyA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_B_PA1B204_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)
3ojy COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo
sapiens)
3 / 3 GLY B  88
ASN B  87
ARG B 157
None
CA  B 538 (-2.8A)
None
0.69A 5w7bD-3ojyB:
undetectable
5w7bD-3ojyB:
8.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_B_BEZB201_0
(NS3 PROTEASE)
3ojy COMPLEMENT COMPONENT
C8 ALPHA CHAIN
COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo
sapiens;
Homo
sapiens)
4 / 5 HIS A 186
ALA B 122
SER B 123
GLY B 134
None
1.23A 5yodB-3ojyA:
undetectable
5yodB-3ojyA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FK2_A_SORA302_0
(GALECTIN-3)
3ojy COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo
sapiens)
4 / 4 ARG B 242
GLU B 301
GLU B 211
ARG B 374
None
1.22A 6fk2A-3ojyB:
undetectable
6fk2A-3ojyB:
14.08