SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oka'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_A_SAMA105_0
(MET REPRESSOR)		 3oka GDP-MANNOSE-DEPENDEN
T
ALPHA-(1-6)-PHOSPHAT
IDYLINOSITOL
MONOMANNOSIDE
MANNOSYLTRANSFERASE
(Corynebacterium
glutamicum) 		5 / 10 ALA A  95
PHE A  92
GLY A  93
LEU A 144
PRO A 163
 None
 1.26A 1cmcA-3okaA:
undetectable
1cmcB-3okaA:
undetectable		 1cmcA-3okaA:
17.61
1cmcB-3okaA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_B_H4BB1001_1
(HYPOTHETICAL PROTEIN
PH0634)		 3oka GDP-MANNOSE-DEPENDEN
T
ALPHA-(1-6)-PHOSPHAT
IDYLINOSITOL
MONOMANNOSIDE
MANNOSYLTRANSFERASE
(Corynebacterium
glutamicum) 		5 / 10 PHE A 155
GLU A 316
HIS A 167
THR A 117
GLU A 121
 None
 1.44A 2dttA-3okaA:
undetectable
2dttB-3okaA:
undetectable		 2dttA-3okaA:
16.53
2dttB-3okaA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_B_J01B600_1
(ORF12)		 3oka GDP-MANNOSE-DEPENDEN
T
ALPHA-(1-6)-PHOSPHAT
IDYLINOSITOL
MONOMANNOSIDE
MANNOSYLTRANSFERASE
(Corynebacterium
glutamicum) 		5 / 11 ALA A 308
THR A 317
ALA A 280
GLY A 309
ARG A 210
 None
None
None
None
SO4  A 601 ( 4.1A)
 1.18A 2xfsB-3okaA:
undetectable		 2xfsB-3okaA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_0
(REPRESSOR PROTEIN
MPHR(A))		 3oka GDP-MANNOSE-DEPENDEN
T
ALPHA-(1-6)-PHOSPHAT
IDYLINOSITOL
MONOMANNOSIDE
MANNOSYLTRANSFERASE
(Corynebacterium
glutamicum) 		5 / 12 THR A 164
LEU A  25
VAL A   9
ILE A  29
THR A  31
 None
 1.39A 3frqA-3okaA:
undetectable		 3frqA-3okaA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_C_DX2C270_1
(PTERIDINE REDUCTASE
1)		 3oka GDP-MANNOSE-DEPENDEN
T
ALPHA-(1-6)-PHOSPHAT
IDYLINOSITOL
MONOMANNOSIDE
MANNOSYLTRANSFERASE
(Corynebacterium
glutamicum) 		4 / 8 ASP A  13
VAL A  67
LEU A  69
PRO A  70
 None
None
GOL  A 801 ( 4.6A)
None
 0.74A 3jq7C-3okaA:
6.0		 3jq7C-3okaA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RN6_A_15UA301_1
(THROMBIN HEAVY CHAIN)		 3oka GDP-MANNOSE-DEPENDEN
T
ALPHA-(1-6)-PHOSPHAT
IDYLINOSITOL
MONOMANNOSIDE
MANNOSYLTRANSFERASE
(Corynebacterium
glutamicum) 		5 / 10 LEU A 247
LEU A 334
ALA A 277
ALA A 219
GLY A 212
 None
 1.22A 4rn6A-3okaA:
undetectable		 4rn6A-3okaA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 3oka GDP-MANNOSE-DEPENDEN
T
ALPHA-(1-6)-PHOSPHAT
IDYLINOSITOL
MONOMANNOSIDE
MANNOSYLTRANSFERASE
(Corynebacterium
glutamicum) 		3 / 3 LEU A 270
VAL A 200
ASP A 274
 None
 0.59A 4y8wC-3okaA:
undetectable		 4y8wC-3okaA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3oka GDP-MANNOSE-DEPENDEN
T
ALPHA-(1-6)-PHOSPHAT
IDYLINOSITOL
MONOMANNOSIDE
MANNOSYLTRANSFERASE
(Corynebacterium
glutamicum) 		4 / 4 SER A 116
ALA A  94
GLN A  22
THR A  11
 None
 1.45A 5n0wA-3okaA:
1.3		 5n0wA-3okaA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PHH_A_LDPA414_1
(LYSINE-SPECIFIC
DEMETHYLASE 4D)		 3oka GDP-MANNOSE-DEPENDEN
T
ALPHA-(1-6)-PHOSPHAT
IDYLINOSITOL
MONOMANNOSIDE
MANNOSYLTRANSFERASE
(Corynebacterium
glutamicum) 		4 / 6 GLU A 290
ARG A 210
TYR A 296
SER A 205
 GDD  A 701 ( 4.2A)
SO4  A 601 ( 4.1A)
None
GDD  A 701 ( 4.1A)
 1.11A 5phhA-3okaA:
undetectable		 5phhA-3okaA:
20.96